LC3B (MAP1LC3B) (NM_022818) Human Untagged Clone

CAT#: SC108102

MAP1LC3B (untagged)-Human microtubule-associated protein 1 light chain 3 beta (MAP1LC3B)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MAP1LC3B
• Synonyms: ATG8F; LC3B; MAP1A/1BLC3; MAP1LC3B-a
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC108102 sequence for NM_022818 edited (data generated by NextGen Sequencing)
  ATGCCGTCGGAGAAGACCTTCAAGCAGCGGCGCACCTTCGAACAAAGAGTAGAAGATGTC
  CGACTTATTCGAGAGCAGCATCCAACCAAAATCCCGGTGATAATAGAACGATACAAGGGT
  GAGAAGCAGCTTCCTGTTCTGGATAAAACAAAGTTCCTTGTACCTGACCATGTCAACATG
  AGTGAGCTCATCAAGATAATTAGAAGGCGCTTACAGCTCAATGCTAATCAGGCCTTCTTC
  CTGTTGGTGAACGGACACAGCATGGTCAGCGTCTCCACACCAATCTCAGAGGTGTATGAG
  AGTGAGAAAGATGAAGATGGATTCCTGTACATGGTCTGTGCCTCCCAGGAGACGTTCGGG
  ATGAAATTGTCAGTGTAA
  
  Clone variation with respect to NM_022818.4
  30 c=>g;338 a=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_022818 unedited
  CAGAATTTTGTAATACGACTCACTATAGGGGCGGCCGCGATTCGGCACGAGGCAAGGCTC
  GCAGCCACCTCTCGGGAGTGCAGGGCCAGATCCTGTGCCAGCGGCCTTACACGGCCACAG
  TCGGATTCGCTGCCGCAGCAGCCGCCACCCCCAGGAGCCGCCGGGACCCTCGCGTCGTCG
  CCGCCGCCGCCCAGATCCCCACACCATGCCGTCGGAGAAGACCTTCAAGCAGCGGCGCAC
  CTTCGAACAAAGAGTAGAAGATGTCCGACTTATTCGAGAGCAGCATCCAACCAAAATCCC
  GGTGATAATAGAACGATACAAGGGTGAGAAGCAGCTTCCTGTTCTGGATAAAACAAAGTT
  CCTTGTACCTGACCATGTCAACATGAGTGAGCTCATCAAGATAATTAGAAGGCGCTTACA
  GCTCAATGCTAATCAGGCCTTCTTCCTGTTGGTGAACGGACACAGCATGGTCAGCGTCTC
  CACACCAATCTCAGAGGTGTATGAGAGTGAGAAAGATGAAGATGGATTCCTGTACATGGT
  CTGTGCCTCCCAGGAGACGTTCGGGATGAAATTGTCAGTGTAAAACCAGAAAAAATGCAT
  CTCTTCTAGAATTTTTTAAACCCTTACCAAGGAAAAAAAAAGGGATGTTACCAACTGAGA
  TCGATCAGTTCATCTAATCACAGATCATCAAACAGTAGTGTTCCCACCTAGGAGTGTTAG
  GAAAAGTGTGTTGTGTTTCAAGCAGAAAAACTGAGCTCNCAGTGAGCACATTCAGCTTTG
  GAAACTATATTATTTAATGTAGGCTAGCTTGGTTTCAAAATTTAAAGTTTAAAAATAAAT
  ACTTTGCATTCTANAAAAAAAAAAAAACTCGACTCTAGATGGCGGCCGCGTCATAGCTGG
  TTCTGGACAGATCCGGGTGGCATCCTGTGACCCTCCCAGTGCTCTCTGGCCTGGAGTGCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_022818 unedited
  CTATGGCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTAGAATGCAAAGT
  ATTTTATTTTTAAACTTTTAAAATTTGAAAACAAGCTAGCCTACATTAAATAATATAGTT
  TCCAAAGCTGAATGTGCTCACTTGGAGCTCAGTTTTTCTGCTTGAAACACAAACACAACT
  TCCTAACACTCCTAGGTGGGAACACTACTGTTTGATGATCTGTGATTAGATGAACTGATC
  GATCTCAGTTGGTAACATCCCTTTTTTTTTCCTTGGTAAGGGTTTAAAAAATTCTAGAAG
  AGATGCATTTTTTCTGGTTTTACACTGACAATTTCATCCCGAACGTCTCCTGGGAGGCAC
  AGACCATGTACAGGAATCCATCTTCATCTTTCTCACTCTCATACACCTCTGAGATTGGTG
  TGGAGACGCTGACCATGCTGTGTCCGTTCACCAACAGGAAGAAGGCCTGATTAGCATTGA
  GCTGTAAGCGCCTTCTAATTATCTTGATGAGCTCACTCATGTTGACATGGTCAGGTACAA
  GGAACTTTGTTTTATCCAGAACAGGAAGCTGCTTCTCACCCTTGTATCGTTCTATTATCA
  CCGGGATTTTGGTTGGATGCTGCTCTCGAATAAGTCGGACATCTTCTACTCTTTGTTCGA
  AGGTGCGCCGCTGCTTGAAGGTCTTCTCCGACGGCATGGTGTGGGAGATCTGGGCGGCGG
  CGGCGACGACGCGAGGGTCCCGGCGGCTCCTGNAGGTGGCGGCTGCTGCGGCAGCGAATC
  CGACTGTGGCCGTGTAAGGCCGCTGCACAGGATCTGGCCCTGCACTCCGAGAGTGGCTGC
  GAGCTTGCCTCGTGCGAATTCGGCGGCGCCTATAAGTGAGTCGTATACAAATNCTTGACG
  GTCACTAACGAGCCTGCTGAATAGACTNCCACGTACCGCTACGCCATTGCGAAGGGGGCG
  GGGGTATACACTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_022818
• ORF Size: 378 bp
• Insert Size: 930
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_022818.3, NP_073729.1
• RefSeq Size: 2270
• RefSeq ORF: 378
• Locus ID: 81631
• Domains: MAP1_LC3
• Gene Summary: The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq, Jul 2008]