PHPT1 (NM_014172) Human Untagged Clone

CAT#: SC108149

PHPT1 (untagged)-Human phosphohistidine phosphatase 1 (PHPT1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PHPT1
• Synonyms: CGI-202; HEL-S-132P; HSPC141; PHP; PHP14
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC108149 sequence for NM_014172 edited (data generated by NextGen Sequencing)
  ATGGCGGTGGCGGACCTCGCTCTCATTCCTGATGTGGACATCGACTCCGACGGCGTCTTC
  AAGTATGTGCTGATCCGAGTCCACTCGGCTCCCCGCTCCGGGGCTCCGGCTGCAGAGAGC
  AAGGAGATCGTGCGCGGCTACAAGTGGGCTGAGTACCATGCGGACATCTACGACAAAGTG
  TCGGGCGACATGCAGAAGCAAGGCTGCGACTGTGAGTGTCTGGGCGGCGGGCGCATCTCC
  CACCAGAGTCAGGACAAGAAGATTCACGTGTACGGCTATTCCATGGCCTATGGTCTTGCC
  CAGCACGCCATTTCAACTGAGAAAATCAAAGCCAAGTACCCCGACTACGAGGTCACCTGG
  GCTAACGACGGCTACTGA
  
  Clone variation with respect to NM_014172.4
  296 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014172 unedited
  GCACGAGGCCGGGAGGAGGAACATGGCGGTGGCGGACCTCGCTCTCATTCCTGATGTGGA
  CATCGACTCCGACGGCGTCTTCAAGTATGTGCTGATCCGAGTCCACTCGGCTCCCCGCTC
  CGGGGCTCCGGCTGCAGAGAGCAAGGAGATCGTGCGCGGCTACAAGTGGGCTGAGTACCA
  TGCGGACATCTACGACAAAGTGTCGGGCGACATGCAGAAGCAAGGCTGCGACTGTGAGTG
  TCTGGGCGGCGGGCGCATCTCCCACCAGAGTCAGGACAAGAAGATTCACGTGTACGGCTA
  TTCCATGGCCTATGGTCTTGCCCAGCACGCCATTTCAACTGAGAAAATCAAAGCCAAGTA
  CCCCGACTACGAGGTCACCTGGGCTAACGACGGCTACTGAGCACTCCCAGCCCGGGGCCT
  GCTGCCTCCAGCAGCCACTTCAGAGCCCCCGCCTTTGCCTGCACTCCTCTTGCAGGGCTG
  GCCCTGCCTGCTCCTGCGGCAGCCTCTGGTGACGTGCTGTCCACCAGGCCTTGGAGACAG
  GCTAGCCTGGCCACAGAATTAAACGTGTTGCCACACCTGCCGGCTTCTGAAAAAAAAAAA
  AAAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_014172
• ORF Size: 378 bp
• Insert Size: 660
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_014172.2, NP_054891.2
• RefSeq Size: 903
• RefSeq ORF: 378
• Locus ID: 29085
• Domains: Ocnus
• Protein Families: Druggable Genome
• Protein Pathways: Fructose and mannose metabolism, Metabolic pathways, Riboflavin metabolism, Thiamine metabolism
• Gene Summary: This gene encodes an enzyme that catalyzes the reversible dephosphorylation of histidine residues in proteins. It may be involved in the dephosphorylation of G-beta and ATP citrate lyase and in negatively regulating CD4 T lymphocytes by dephosphorylation and inhibition of KCa3.1 channels. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
  Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 5' coding region, compared to variant 4. It encodes isoform 3, which is shorter than isoform 4.