USP2 (NM_004205) Human Untagged Clone

CAT#: SC108156

USP2 (untagged)-Human ubiquitin specific peptidase 2 (USP2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: USP2
• Synonyms: UBP41; USP9
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC108156 sequence for NM_004205 edited (data generated by NextGen Sequencing)
  ATGTCCCAGCTCTCCTCCACCCTGAAGCGCTACACAGAATCGGCCCGCTACACAGATGCC
  CACTATGCCAAGTCGGGCTATGGTGCCTACACCCCGTCCTCCTATGGGGCCAATCTGGCT
  GCCTCCTTACTGGAGAAGGAGAAACTTGGTTTCAAGCCGGTCCCCACCAGCAGCTTCCTC
  ACCCGTCCCCGTACCTATGGCCCCTCCTCCCTCCTGGACTATGACCGGGGCCGCCCCCTG
  CTGAGACCCGACATCACTGGGGGTGGTAAGCGGGCAGAGAGCCAGACCCGGGGTACTGAG
  CGGCCTTTAGGCAGTGGCCTCAGCGGGGGCAGCGGATTCCCTTATGGAGTGACCAACAAC
  TGCCTCAGCTACCTGCCCATCAATGCCTATGACCAGGGGGTGACCCTAACCCAGAAGCTG
  GACAGCCAATCAGACCTGGCCCGGGATTTCTCCAGCCTCCGGACCTCAGATAGCTACCGG
  ATAGACCCCAGGAACCTGGGCCGCAGCCCCATGCTGGCCCGGACGCGCAAGGAGCTCTGC
  ACCCTGCAGGGGCTCTACCAGACAGCCAGCTGCCCTGAATACCTGGTCGACTACCTGGAG
  AACTATGGTCGCAAGGGCAGTGCATCTCAGGTGCCCTCCCAGGCCCCTCCCTCACGAGTC
  CCTGAAATCATCAGCCCAACCTACCGACCCATTGGCCGCTACACGCTGTGGGAGACGGGA
  AAGGGTCAGGCCCCTGGGCCCAGCCGCTCCAGCTCCCCGGGAAGAGACGGCATGAATTCT
  AAGAGTGCCCAGGGTCTGGCTGGTCTTCGAAACCTTGGGAACACGTGCTTCATGAACTCA
  ATTCTGCAGTGCCTGAGCAACACTCGGGAGTTGAGAGATTACTGCCTCCAGAGGCTCTAC
  ATGCGGGACCTGCACCACGGCAGCAATGCACACACAGCCCTCGTGGAAGAGTTTGCAAAA
  CTAATTCAGACCATATGGACTTCATCCCCCAATGATGTGGTGAGCCCATCTGAGTTCAAG
  ACCCAGATCCAGAGATACGCACCGCGCTTTGTTGGCTATAATCAGCAGGATGCTCAGGAG
  TTCCTTCGCTTTCTTCTGGATGGGCTCCATAACGAGGTGAACCGAGTGACACTGAGACCT
  AAGTCCAACCCTGAGAACCTCGATCATCTTCCTGATGACGAGAAAGGCCGACAGATGTGG
  AGAAAATATCTAGAACGGGAAGACAGTAGGATCGGGGATCTCTTTGTTGGGCAGCTAAAG
  AGCTCGCTGACGTGTACAGATTGTGGTTACTGTTCTACGGTCTTCGACCCCTTCTGGGAC
  CTCTCACTGCCCATTGCTAAGCGAGGTTATCCTGAGGTGACATTAATGGACTGCATGAGG
  CTCTTCACCAAAGAGGATGTGCTTGATGGAGATGAAAAGCCAACATGCTGTCGCTGCCGA
  GGCAGAAAACGGTGTATAAAGAAGTTCTCCATCCAGAGGTTCCCAAAGATCTTGGTGCTC
  CATCTGAAGCGGTTCTCAGAATCCAGGATCCGAACCAGCAAGCTCACAACATTTGTGAAC
  TTCCCCCTAAGAGACCTGGACTTAAGAGAATTTGCCTCAGAAAACACCAACCATGCTGTT
  TACAACCTGTACGCTGTGTCCAATCACTCCGGAACCACCATGGGTGGCCACTATACAGCC
  TACTGTCGCAGTCCAGGGACAGGAGAATGGCACACTTTCAACGACTCCAGCGTCACTCCC
  ATGTCCTCCAGCCAAGTGCGCACCAGCGACGCCTACCTGCTCTTCTACGAACTGGCCAGC
  CCGCCCTCCCGAATGTAG
  
  Clone variation with respect to NM_004205.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004205 unedited
  AATTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGAGGTGGGAGA
  GAGTCAGGCAGGAGCCGAGGCCGGGGAGCCCTCTTCGTCAGCTGGTGCTCACTGCGCCGC
  GCCAGCGCCAGCCGGGACTCACCCGCAGCTCCATGCTTGTGCCCGGTTCGACTCGTCCAT
  CCTCCAAGAAGAGGCAGCCCATGAGGCTCCCAGTCCCCACTGAGTGCCACCCTGAAGGAT
  GTCCCAGCTCTCCTCCACCCTGAAGCGCTACACAGAATCGGCCCGCTACACAGATGCCCA
  CTATGCCAAGTCGGGCTATGGTGCCTACACCCCGTCCTCCTATGGGGCCAATCTGGCTGC
  CTCCTTACTGGAGAAGGAGAAACTTGGTTTCAAGCCGGTCCCCACCAGCAGCTTCCTCAC
  CCGTCCCCGTACCTATGGCCCCTCCTCCCTCCTGGACTATGACCGGGGCCGCCCCCTGCT
  GAGACCCGACATCACTGGGGGTGGTAAGCGGGCAGAGAGCCAGACCCGGGGTACTGAGCG
  GCCTTTAGGCAGTGGCCTCAGCGGGGGCAGCGGATTCCCTTATGGAGTGACCAACAACTG
  CCTCAGCTACCTGCCCATCAATGCCTATGACCACGGGGTGACCCTAACCCAGAAGCTGGA
  CAGCCAATCAGACCTGGCCCGGGATTTCTCCAGCCTCCGGACCTCATATAGCTACCGGAT
  AGACCCCAGGAACCTGGGCCGCAGCCCCATGCTGGCCCGGACGCGCCAAGAGCTCTGCAC
  CCTGGCAGGGCTCTACCANACAGCCAGCTGCCCTGAATACCTGGTCGACTACCTGGAGAA
  CTTGGGGCGCCAGGGCAGTGCATCTACAGTGCCCTCCCAGGCCCCCTCCCTCACGAGTCC
  CTGAAATCATTAGCCCAACCTACCGACCCATTTGGCCGCGTCCCCCTGTGGGGAGACCGG
  GAAAGGGTCATGCCCCTGGGCCCAGCCCCTCCACCTTCCGGGAAGGAACGCTTGGATTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' genomic read for NM_004205 unedited
  NCAACTATGNAACCGCGGCCGCAATCTANGATCGAGTTTTTTTTTTTTTTTTTTTGATTT
  CTCAAANCTATTATTTATTCTGTACAAGGTTCCACTGTACATTAGACATTCTTCTACTCT
  TGCTTACACAGTAAACAAGTGTACACTTGCCCTTGGGCTCAGGTTCACAGGTCTTCTCTG
  GAGAAGGGTGTCAGGCCAGTAAAACTCAGGGTGTCTTTCTCTGATGCCTCCTCCTAGGAG
  CCTGGAATGTGCCAGGCTCCACGGGGCACAAGCCGGGCCCAGCTGTGTGGGTGAACAGCT
  TTACTCTCCAGGACAGCACAGAGTTTTATCCAACTATGTAGGGCAAAATTGAGCCCACAG
  GAAAGAACCATACAACTGAGGCAAGATGTCCCCAAATACCCAGGCTCCAGCTCCCAGGGC
  AGGACTGGAGACCAGCGCTAAGAAGAGCTGAGGGGTGGCCTGGGCATCCCTGAGAAACTC
  GGTCCAAAGGGCCTATTGTCTAGGAGGCTCTGAGAAGGGGGCGGGGGCAGGAAGGCCAGG
  GGGAAAGGGATGTTAAGAGAATAAATAAAAGGGAGAGAAGCTCTAGGGACGAGGGGCTTG
  TGCTATCCTTCAAACAGCTGGGGAGCAGACCANGGGTGGGCTAGAGGACGTGGGCGGGAA
  AGACTTGATGCCCTGTCNGAAGGAATCTACCTGCTTTCTTCTTTGCCTCACTGCAATGCA
  CAACGAGCCAAGGCTAAAGGCAGGATTCCCTTTCCCAGGCCGGTTTGAACAGAGCACTGG
  GGGAAAAAGGAAAAAGCTTGAGGGAAATTTTCGGGAGGGGCCAGTTACCCCCTGGGTCCC
  CAAATGCTTTAAAGCAACAATTCTGGGAGGCCACTTAATTTCCCTTCCAAACTTTAAAAA
  AAAAAAAAAAAAACCCCCACCCCCCAAAAAGAAACTTGGTTTAAATTCCAAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004205
• ORF Size: 1818 bp
• Insert Size: 4400
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_004205.3, NP_004196.3
• RefSeq Size: 2633
• RefSeq ORF: 1818
• Locus ID: 9099
• Domains: UCH
• Protein Families: Protease
• Gene Summary: This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
  Transcript Variant: This variant (1) encodes the longest isoform (a).