ATP dependent metalloprotease YME1L1 (YME1L1) (NM_139313) Human Untagged Clone

CAT#: SC108204

YME1L1 (untagged)-Human YME1-like 1 (S. cerevisiae) (YME1L1), nuclear gene encoding mitochondrial protein, transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: YME1L1
• Synonyms: FTSH, MEG4, PAMP, YME1L
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_139313, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTTTTCCTTGTCGAGCACGGTGCAACCCCAGGTTACAGTTCCTCTGAGTCATCTCATCAATGCCTTCC
  ATACACCAAAAAACACTTCTGTTTCTCTCAGTGGAGTGTCAGTTTCTCAAAACCAGCATCGAGATGTAGT
  TCCTGAGCATGAGGCTCCCAGCAGTGAGTGTATGTTCAGTGACTTCCTGACGAAGCTTAACATTGTTTCA
  ATTGGCAAAGGAAAAATATTCGAAGGGTACAGATCCATGTTCATGGAGCCAGCAAAAAGGATGAAGAAGA
  GCTTGGACACAACCGATAACTGGCACATCCGTCCAGAACCCTTCTCCCTCTCAATCCCTCCTTCACTTAA
  CTTAAGGGACCTTGGATTATCTGAACTAAAAATTGGACAGATTGATCAGCTGGTAGAAAATCTACTTCCT
  GGATTTTGTAAAGGCAAAAACATTTCTTCCCATTGGCATACATCCCATGTCTCTGCACAATCCTTCTTTG
  AAAATAAATATGGTAACTTAGATATATTTAGTACATTACGTTCCTCTTGCTTGTATCGACATCATTCAAG
  AGCTCTTCAAAGCATTTGTTCAGATCTTCAGTACTGGCCAGTTTTCATACAGTCTCGGGGTTTTAAAACT
  TTGAAATCAAGGACACGACGTCTCCAGTCTACCTCCGAGAGATTAGCTGAAACACAGAATATAGCGCCAT
  CATTCGTGAAGGGGTTTCTTTTGCGGGACAGAGGATCAGATGTTGAGAGTTTGGACAAACTCATGAAAAC
  CAAAAATATACCTGAAGCTCACCAAGATGCATTTAAAACTGGTTTTGCGGAAGGTTTTCTGAAAGCTCAA
  GCACTCACACAAAAAACCAATGATTCCCTAAGGCGAACCCGTCTGATTCTCTTCGTTCTGCTGCTATTCG
  GCATTTATGGACTTCTAAAAAACCCATTTTTATCTGTCCGCTTCCGGACAACAACAGGGCTTGATTCTGC
  AGTAGATCCTGTCCAGATGAAAAATGTCACCTTTGAACATGTTAAAGGGGTGGAGGAAGCTAAACAAGAA
  TTACAGGAAGTTGTTGAATTCTTGAAAAATCCACAAAAATTTACTATTCTTGGAGGTAAACTTCCAAAAG
  GAATTCTTTTAGTTGGACCCCCAGGGACTGGAAAGACACTTCTTGCCCGAGCTGTGGCGGGAGAAGCTGA
  TGTTCCTTTTTATTATGCTTCTGGATCCGAATTTGATGAGATGTTTGTGGGTGTGGGAGCCAGCCGTATC
  AGAAATCTTTTTAGGGAAGCAAAGGCGAATGCTCCTTGTGTTATATTTATTGATGAATTAGATTCTGTTG
  GTGGGAAGAGAATTGAATCTCCAATGCATCCATATTCAAGGCAGACCATAAATCAACTTCTTGCTGAAAT
  GGATGGTTTTAAACCCAATGAAGGAGTTATCATAATAGGAGCCACAAACTTCCCAGAGGCATTAGATAAT
  GCCTTAATACGTCCTGGTCGTTTTGACATGCAAGTTACAGTTCCAAGGCCAGATGTAAAAGGTCGAACAG
  AAATTTTGAAATGGTATCTCAATAAAATAAAGTTTGATCAATCCGTTGATCCAGAAATTATAGCTCGAGG
  TACTGTTGGCTTTTCCGGAGCAGAGTTGGAGAATCTTGTGAACCAGGCTGCATTAAAAGCAGCTGTTGAT
  GGAAAAGAAATGGTTACCATGAAGGAGCTGGAGTTTTCCAAAGACAAAATTCTAATGGGGCCTGAAAGAA
  GAAGTGTGGAAATTGATAACAAAAACAAAACCATCACAGCATATCATGAATCTGGTCATGCCATTATTGC
  ATATTACACAAAAGATGCAATGCCTATCAACAAAGCTACAATCATGCCACGGGGGCCAACACTTGGACAT
  GTGTCCCTGTTACCTGAGAATGACAGATGGAATGAAACTAGAGCCCAGCTGCTTGCACAAATGGATGTTA
  GTATGGGAGGAAGAGTGGCAGAGGAGCTTATATTTGGAACCGACCATATTACAACAGGTGCTTCCAGTGA
  TTTTGATAATGCCACTAAAATAGCAAAGCGGATGGTTACCAAATTTGGAATGAGTGAAAAGCTTGGAGTT
  ATGACCTACAGTGATACAGGGAAACTAAGTCCAGAAACCCAATCTGCCATCGAACAAGAAATAAGAATCC
  TTCTAAGGGACTCATATGAACGAGCAAAACATATCTTGAAAACTCATTCTTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_139313 unedited
  GGGGGTTCAAATTTTGTATACGACTCACTATAGGCGGCCGCGAATTCGGCACGAGGGGAG
  GCCATTTTCCGTTTCTGGGAGGAGTGAGGGGCAACGGGTCGGAGAAAAAGGAAAAAAGAA
  GGGCTCAGCGCCTCCCCGCCGGGCCGTGGACAGAGGGGCACAGTTTCGGCAGGCGGGTGA
  GGTCGCTGAGGGCCCGCCGGAGATGTTTTCCTTGTCGAGCACGGTGCAACCCCAGGTTAC
  AGTTCCTCTGAGTCATCTCATCAATGCCTTCCATACACCAAAAAACACTTCTGTTTCTCT
  CAGTGGAGTGTCAGTTTCTCAAAACCAGCATCGAGATGTAGTTCCTGAGCATGAGGCTCC
  CAGCAGTGAGTGTATGTTCAGTGACTTCCTGACGAAGCTTAACATTGTTTCAATTGGCAA
  AGGAAAAATATTCGAAGGGTACAGATCCATGTTCATGGAGCCAGCAAAAAGGATGAAGAA
  GAGCTTGGACACAACCGATAACTGGCACATCCGTCCAGAACCCTTCTCCCTCTCAATCCC
  TCCTTCACTTAACTTAAGGGACCTTGGATTATCTGAACTAAAAATTGGACAGATTGATCA
  GCTGGTAGAAAATCTACTTCCTGGATTTTGTAAAGGCAAAAACATTTCTTCCCATTGGCA
  TACATCCCATGTCTCTGCACAATCCTTCTTTGAAAATAAATATGGTAACTTAGATATATT
  TAGTACATTACGTTCCTCTTGCTTGTATCGACATCATTCAAGAGCTCTTCAAGCATTTGT
  TCAGATCTTCAGTACTGGCCAGCATTAATTTGGAGATTCTGNACAATATGATTTAAAAGA
  AAACGAAATGAGCCATATTTTTCATACAGNTCTCGGGGTTTTTAAAACTTTNGAATCANG
  GACACGACGTCTTCAGTCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_139313 unedited
  NAAATNCGAGTTTTTTTTTTTTTTTTTTTTTTGTTTTCAAACCTGATAGTTCTTTATTTG
  GGAAAATATATTTGCCATGGGATGCTAATTTGCAATAGGTGTCATAATGAGAATAACCCA
  AACTGGATAAATGTGACAAATGATTGACAAAGCATTTCACACCCTTCAATTACACCACAT
  CAAGAATGAGGGGAAAGCGTTGTAAAAGTAGACTACTGGGATGCTACTTATATTCTTGCA
  ATAAAACCAGCAAGCATCCATATCAAGAGAGTTATCATCTCACTTCCAACTTTTTCCCCT
  CAAGAACAATTTGAATCTCTTTGGCATCCAAAGTCTCATAGGTCAATAAAGCTTCTGCGA
  GATTCTTATGCTCCTTTGCATGAGTTTTCAAGATATGTTTTGCTCGTTCATATGAGTCCC
  TTAAAAAGATTCTTATTTCTTGTTCGATGGCAGATTGGGTTTCTGGACTTAGTTTCCCTG
  TATCACTGTAGGTCATAACTCCAAGCTTTTCACTCATTCCAAATTTGGTAACCATCCGCT
  TTGCTATTTTAGTGGCATTATCAAAATCACTGGAAGCACCTGTTGTAATATGGTCGGTTC
  CAAATATAAGCTCCTCTGCCACTCTTCCTCCCATACTAACATCCATTTGTGCAAGCAGCT
  GGGCCTCTATTTCATTCCATCTGTCATTCTCAGGTAACAGGGACACATGTCCAAATGTTG
  GCCCCCGTGGCATGATTGTACCTTTGTTGGAAGGCATTGCATCTTTTGTGTAATATGCAA
  AAAGGGCTGACCAAATTTCTGATATGCTGGGATGCTTTTGCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_139313
• ORF Size: 2223 bp
• Insert Size: 2750
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_139313.1, NP_647474.1
• RefSeq Size: 2584
• RefSeq ORF: 2223
• Locus ID: 10730
• Domains: Peptidase_M41, AAA, AAA
• Protein Families: Druggable Genome, Protease
• Gene Summary: The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
  Transcript Variant: This variant (2) is missing a segment of the coding region at the 3' end compared to transcript variant 1. This results in an isoform (2) that is shorter at the C-terminus compared to isoform 1.