MAX (NM_145112) Human Untagged Clone

CAT#: SC108216

MAX (untagged)-Human MYC associated factor X (MAX), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MAX
• Synonyms: bHLHd4
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_145112, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGCGATAACGATGACATCGAGGTGGAGAGCGACGCTGACAAACGGGCTCATCATAATGCACTGGAAC
  GAAAACGTAGGGACCACATCAAAGACAGCTTTCACAGTTTGCGGGACTCAGTCCCATCACTCCAAGGAGA
  GAAGGCATCCCGGGCCCAAATCCTAGACAAAGCCACAGAATATATCCAGTATATGCGAAGGAAAAACCAC
  ACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCTTCTGGAGCAGCAAGTCCGTGCACTGG
  AGAAGGCGAGGTCAAGTGCCCAACTGCAGACCAACTACCCCTCCTCAGACAACAGCCTCTACACCAACGC
  CAAGGGCAGCACCATCTCTGCCTTCGATGGGGGCTCGGACTCCAGCTCGGAGTCTGAGCCTGAAGAGCCC
  CAAAGCAGGAAGAAGCTCCGGATGGAGGCCAGCTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_145112 unedited
  GGGGTCAACATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGTGAGTG
  AGTGAGTGTGTGTGTGGGGGGGACTCGGCTTGTTGTTGTCGGTGACTTCCCCCTCCCCTT
  CACCCCTTCCCCTCCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAATGAGC
  GATAACGATGACATCGAGGTGGAGAGCGACGCTGACAAACGGGCTCATCATAATGCACTG
  GAACGAAAACGTAGGGACCACATCAAAGACAGCTTTCACAGTTTGCGGGACTCAGTCCCA
  TCACTCCAAGGAGAGAAGGCATCCCGGGCCCAAATCCTAGACAAAGCCACAGAATATATC
  CAGTATATGCGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAG
  AATGCTCTTCTGGAGCAGCAAGTCCGTGCACTGGAGAAGGCGAGGTCAAGTGCCCAACTG
  CAGACCAACTACCCCTCCTCAGACAACAGCCTCTACACCAACGCCAAGGGCAGCACCATC
  TCTGCCTTCGATGGGGGCTCGGACTCCACCTACGAGTCTGAGCCTGAAGAGCCCCAAAGC
  AGGAAGAAGCTCCGGATGGAGGCCAGCTAAGCCACTCGGGGCAGGCCAGCAATAAAAACT
  GTCTGTCTCCATCCGCTCATCCTCCTTTCAGTTCGTTGGTAGAGCCCTCAGGACCATTTA
  AGAGACTCTTTATTTTTCACTCTTCTCCTTTTTTTTNTAAAATTTTATTTTTACGTAGAA
  GCTTACTGACAACAGCTTTCGTTCTTCTTCCCCATTTCCCTGGATATTTTTAATGGATTC
  CCTTCAGGATTCCCTGTCCCCACGGGAATTTTAACCAAACACCCCACCTGGCACTTTTTC
  TGTGGAGACCACGGCGGCCGACC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_145112 unedited
  GGGTAGAAATCTTTATGTCTTATGTAAGGGGCGAAGCTTACTTGCAAGACATTTTTCGGC
  AGTATGTACAACATACTTTCCTATTTCCATGGAATGGAATCAAACACGAACTGAGACTAC
  AGAGTATACACTAGCAAATCAGCAAATGCCAGGAACGGAGTACGCAAAAAGACAAAGAAA
  TGAGGCCTAAACACACAAAACCCTTCACTGGCATCTGCTGACCACAGCCAGAACCAGGGC
  CTGGATCACACAATGGAGACAGGTTCCAGGACAGTAGGAAAGGAAGTGGGATGAGGGCTG
  GGAAGGGTCCGCACTGGGGCGCGGGCCTACTACCAGGTAAATTGCTCCTTGGTATTTACA
  TACAAAATCAGGTGGCTCTATTTCTTACAAATACACACGGGAAGAAAGAAAGATTTCATT
  ATTACTTTATGAATCTGCCGCTTTGTAAGACCGACATCATCAGAAATAGGTACAATCCAC
  TGAGATTCAAATTTAAGTAGCAGGAAATAAATATCAAAACATCATCACTGGCTCTGCATA
  CAAAACCTCTATGCTACTCAAAACACCCTCCCTGTCGCAACCCCAAATGGCCACTCCTTG
  GTGGCTGCTGCTTCACTGCTGGCACTCTCCCTCCCTATTACGAGAGTGTCACACGGTCCT
  CCGCGCAGGCTGGCGCCGTANGCTCAATCCGCTGGTTGAGAGAATCACGACGAAACCCTT
  CTCCGATCTGCGCTGCAATCCGCCTTACTTCCTTTTACCCACAAACCTCTTTAAGATCCG
  GGCTTCCATACGAGCGATCATACTCCTTAAAAAAAGAACCCAAACACCCTCATAGGAGAG
  CGGCCATTTGGGCATCCCACCGTCCATTTCCATACCGTGTTCCCCACCTCACCGTTTCCC
  ATTGCGGTTGTCCCCGAGCTTTCCGCCGTTGCCCCCCCGGCATTCCCTGCATGCTGCCGA
  CCGTTGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_145112
• Insert Size: 2210 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_145112.1, NP_660087.1
• RefSeq Size: 2041 bp
• RefSeq ORF: 456 bp
• Locus ID: 4149
• Cytogenetics: 14q23.3
• Domains: HLH
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: MAPK signaling pathway, Pathways in cancer, Small cell lung cancer
• Gene Summary: 'The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]'
  Transcript Variant: This variant (2) lacks an alternate in-frame exon in the coding region compared to variant 1. It encodes isoform b (also known as the short form) which is shorter than isoform a.