ZNF384 (NM_133476) Human Untagged Clone

CAT#: SC108238

ZNF384 (untagged)-Human zinc finger protein 384 (ZNF384), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ZNF384
• Synonyms: CAGH1; CAGH1A; CIZ; ERDA2; NMP4; NP; TNRC1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC108238 sequence for NM_133476 edited (data generated by NextGen Sequencing)
  ATGGAAGAATCTCACTTCAATTCTAACCCGTACTTCTGGCCTTCTATCCCCACAGTCTCA
  GGTCAGATCGAGAACACAATGTTCATCAACAAGATGAAGGATCAGCTGTTGCCAGAGAAG
  GGCTGTGGTCTGGCCCCACCTCACTACCCCACCTTGCTGACAGTGCCTGCCTCAGTGTCC
  CTGCCCTCAGGCATCAGTATGGACACAGAGTCCAAGTCAGACCAGCTGACCCCACACAGC
  CAAGCGTCCGTTACCCAGAATATCACGGTGGTCCCTGTGCCGTCTACAGGACTGATGACT
  GCTGGAGTCTCCTGTTCTCAGAGGTGGAGAAGAGAAGGGAGTCAATCAAGGGGTCCGGGT
  TTGGTAATCACGTCCCCCTCAGGCTCTCTTGTGACCACAGCATCATCAGCTCAGACCTTC
  CCCATTTCGGCTCCCATGATTGTCTCAGCTCTTCCCCCTGGCTCACAAGCCCTGCAGGTT
  GTCCCTGACCTCTCCAAGAAGGTAGCATCGACCCTAACCGAGGAAGGAGGCGGAGGTGGT
  GGTGGAGGTGGCAGTGTGGCTCCTAAGCCACCCCGGGGCCGGAAGAAGAAGCGGATGCTG
  GAATCAGGGCTGCCCGAGATGAATGACCCTTATGTCCTCTCCCCTGAGGATGATGATGAC
  CATCAGAAAGACGGCAAGACCTACAGGTGCCGGATGTGCTCACTGACATTCTACTCCAAG
  TCGGAGATGCAGATCCACTCCAAGTCACACACCGAGACCAAGCCCCACAAGTGCCCACAT
  TGCTCCAAGACCTTCGCCAACAGCTCCTACCTGGCCCAGCACATCCGTATACACTCAGGG
  GCTAAGCCCTACAGTTGTAACTTCTGTGAGAAATCCTTCCGCCAGCTCTCCCACCTTCAG
  CAGCACACCCGAATCCACACTGGTGATAGACCATACAAATGTGCACACCCAGGCTGTGAG
  AAAGCCTTCACACAACTCTCCAATCTGCAGTCCCACAGACGGCAACACAACAAAGATAAA
  CCCTTCAAGTGCCACAACTGTCATCGGGCGTACACGGATGCAGCCTCACTAGAGGTGCAC
  CTGTCTACGCACACAGTGAAGCATGCCAAGGTGTACACCTGCACTATCTGCAGTCGGGCA
  TACACATCAGAAACATACCTTATGAAACATATGCGCAAACACAACCCGCCTGATCTTCAG
  CAACAGGTGCAGGCAGCAGCAGCAGCGGCAGCAGTGGCCCAGGCCCAGGCTCAAGCTCAA
  GCCCAGGCTCAGGCTCAGGCTCAAGCCCAGGCCCAGGCCCAGGCCTCCCAGGCATCACAG
  CAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCCACCACCACACTTC
  CAGTCTCCTGGGGCAGCCCCCCAGGGTGGGGGTGGTGGGGACAGCAATCCCAACCCTCCA
  CCCCAGTGTTCCTTTGACCTGACCCCGTATAAGACGGCGGAGCATCATAAGGACATCTGC
  CTCACTGTCACCACCAGCACCATCCAGGTGGAGCACCTGGCCAGCTCTTAG
  
  Clone variation with respect to NM_133476.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_133476 unedited
  AATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCTAGACTGCTGTTATTATA
  TCCACCCGTCTTTGGATTGCTGGCTGGGGGGTCTGCCTGCCTTCCAGACTGACTGCTGAC
  AAATAATTCCTGAGGTTCTCCACAGTTCTCTGGTGGCTGCACCCTGCCTGGCCCCTGTAA
  CCTAGACAATTTGTTTACAGAAAGTTCAGGAGCCCTGGAAAGGAGAAGGAATAAGACGGC
  AGGAGGAAGAGAGAGAGAGGGTAGAATGGAAGAATCTCACTTCAATTCTAACCCGTACTT
  CTGGCCTTCTATCCCCACAGTCTCAGGTCAGATCGAGAACACAATGTTCATCAACAAGAT
  GAAGGATCAGCTGTTGCCAGAGAAGGGCTGTGGTCTGGCCCCACCTCACTACCCCACCTT
  GCTGACAGTGCCTGCCTCAGTGTCCCTGCCCTCAGGCATCAGTATGGACACAGAGTCCAA
  GTCAGACCAGCTGACCCCACACAGCCAAGCGTCCGTTACCCAGAATATCACGGTGGTCCC
  TGTGCCGTCTACAGGACTGATGACTGCTGGAGTCTCCTGTTCTCAGAGGTGGAGAAGAGA
  AGGGAGTCAATCAAGGGGTCCGGGTTTGGTAATCACGTCCCCCTCAGGCTCTCTTGTGAC
  CACAGCATCATCAGCTCAGACCTTCCCCATTTCGGCTCCCATGATTGTCTCAGCTCTTCC
  CCCTGGCTCACAAGCCCTGCAGGTTGTCCCTGACCTCTNCAAGNAAGTAGCATCGACCCT
  AACCGAGAANNGAGCNGANGNNTGTGTGGAGGTGNCAANTGTGCTCCTAAGCCACCCCGN
  GCCNGAAGAAAAAGCGATGCTGNAATCAGGGGCTGCCGAGATGATGACCCTTATGTNCTC
  TCCCCTGAGATGATGATGACATCANAAGACNGCAGACCTACAGTGCCCGATTGCTCCTGA
  ATTTACTTCAGTCGAGAGCGGATCCCTCAGT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_133476 unedited
  GAGAGAGCACTGGGGNAGGGTCACAGGGCAGCCACCCGGGTATCTGTTCAGGAAAACAGC
  TATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCAGAGATAATGCA
  TTTATAAACACAGAAAATGGTTACAACAAAGATGGCCGTGAATGAGTGGGTATAATATAT
  TTATATATATATATTTATATATAAATCCGTGTCCGGCATCTGACTGTGGCACCTAGGGAG
  CTAAGTCCAGTCCTTGCGTTTGCCTTGAACTCTCCCTTCTCCGCAACACCCCTGTTTTGG
  AGTTTCACAGATAACACAAAGCCTCCCACAGCTCCTTGGGGGGTGGTGTTGGGGAGACTG
  AGAGTATAGGGTCTTTGTAGGCAGAGAAGGAGAGAGGCTTCAAGGAAATCCGTAAAACCA
  TAACACACACTTCTAAGCCACCTGTGACCAACTTGGGAATTTCTGGCCCCTTGGGGACCA
  CATCTCAGCCCTTGCCCCCTTCAAATAAAAGGAGGTCTAGCCCCTACCCCAAATCTCCTT
  CTACCAGCAGTCAATAGGAAGCAAAGTGAGACGATGTAGGGGAAGAAATGGCTCTCAGGG
  ACTGAGGCATTTGAGAAACCTCTGTTCTTTTGCAGGCAAAAATAGAACAAGAGGCTGGTT
  GCATTTGGGGCTCCCTTTTCTCTGTTATCTGGGAGGGCCAGCCTCTAGTCTTACATCAGC
  CCAAACTTTGAGGATAAGGAGGGTAAGGATAGGGTAAAGTGGCCACACTGGACAAGGTTC
  TATGAAGTCATAGCAAATCCTTCCCTTGAGCACCGACCCCCATTTTTAAAAACTTTGCTT
  TGGAAGGGAAGGCTGCTGGATGAACCATCAGCTCATTATTCCTC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_133476
• ORF Size: 1551 bp
• Insert Size: 2600
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_133476.2, NP_597733.2
• RefSeq Size: 2906
• RefSeq ORF: 1551
• Locus ID: 171017
• Domains: zf-C2H2
• Protein Families: Transcription Factors
• Gene Summary: This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011]
  Transcript Variant: This variant (2) differs in the 5' UTR and lacks an alternate in-frame exon in the central coding region, compared to variant 7, resulting in an isoform (a) that is shorter than isoform d.