Calnexin (CANX) (NM_001746) Human Untagged Clone

CAT#: SC108288

CANX (untagged)-Human calnexin (CANX), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CANX
• Synonyms: CNX; IP90; P90
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001746 edited
  GGGTCGGGCCGCCTCCGCCTCTCTCTTTACTGCGGCGCGGGGCAAGGTGTGCGGGCGGGA
  AGGGGCACGGGCACCCCCGCGGTCCTCGGGAGGCTAGAGATCATGGAAGGGAAGTGGTTG
  CTGTGTATGTTACTGGTGCTTGGAACTGCTATTGTTGAGGCTCATGATGGACATGATGAT
  GATGTGATTGATATTGAGGATGACCTTGACGATGTCATTGAAGAGGTAGAAGACTCAAAA
  CCAGATACCACTGCTCCTCCTTCATCTCCCAAGGTTACTTACAAAGCTCCAGTTCCAACA
  GGGGAAGTATATTTTGCTGATTCTTTTGACAGAGGAACTCTGTCAGGGTGGATTTTATCC
  AAAGCCAAGAAAGACGATACCGATGATGAAATTGCCAAATATGATGGAAAGTGGGAGGTA
  GAGGAAATGAAGGAGTCAAAGCTTCCAGGTGATAAAGGACTTGTGTTGATGTCTCGGGCC
  AAGCATCATGCCATCTCTGCTAAACTGAACAAGCCCTTCCTGTTTGACACCAAGCCTCTC
  ATTGTTCAGTATGAGGTTAATTTCCAAAATGGAATAGAATGTGGTGGTGCCTATGTGAAA
  CTGCTTTCTAAAACACCAGAACTCAACCTGGATCAGTTCCATGACAAGACCCCTTATACG
  ATTATGTTTGGTCCAGATAAATGTGGAGAGGACTATAAACTGCACTTCATCTTCCGACAC
  AAAAACCCCAAAACGGGTATCTATGAAGAAAAACATGCTAAGAGGCCAGATGCAGATCTG
  AAGACCTATTTTACTGATAAGAAAACACATCTTTACACACTAATCTTGAATCCAGATAAT
  AGTTTTGAAATACTGGTTGACCAATCTGTGGTGAATAGTGGAAATCTGCTCAATGACATG
  ACTCCTCCTGTAAATCCTTCACGTGAAATTGAGGACCCAGAAGACCGGAAGCCCGAGGAT
  TGGGATGAAAGACCAAAAATCCCAGATCCAGAAGCTGTCAAGCCAGATGACTGGGATGAA
  GATGCCCCTGCTAAGATTCCAGATGAAGAGGCCACAAAACCCGAAGGCTGGTTAGATGAT
  GAGCCTGAGTACGTACCTGATCCAGACGCAGAGAAACCTGAGGATTGGGATGAAGACATG
  GATGGAGAATGGGAGGCTCCTCAGATTGCCAACCCTAGATGTGAGTCAGCTCCTGGATGT
  GGTGTCTGGCAGCGACCTGTGATTGACAACCCCAATTATAAAGGCAAATGGAAGCCTCCT
  ATGATTGACAATCCCAGTTACCAGGGAATCTGGAAACCCAGGAAAATACCAAATCCAGAT
  TTCTTTGAAGATCTGGAACCTTTCAGAATGACTCCTTTTAGTGCTATTGGTTTGGAGCTG
  TGGTCCATGACCTCTGACATTTTTTTTGACAACTTTATCATTTGTGCTGATCGAAGAATA
  GTTGATGATTGGGCCAATGATGGATGGGGCCTGAAGAAAGCTGCTGATGGGGCTGCTGAG
  CCAGGCGTTGTGGGGCAGATGAACGAGGCAGCTGAAGAGCGCCCGTGGCTGTGGGTAGTC
  TATATTCTAACTGTAGCCCTTCCTGTGTTCCTGGTTATCCTCTTCTGCTGTTCTGGAAAG
  AAACAGACCAGTGGTATGGAGTATAAGAAAACTGATGCACCTCAACCGGATGTGAAGGAA
  GAGGAAGAAGAGAAGGAAGAGGAAAAGGACAAGGGAGATGAGGAGGAGGAAGGAGAAGAG
  AAACTTGAAGAGAAACAGAAAAGTGATGCTGAAGAAGATGGTGGCACTGTCAGTCAAGAG
  GAGGAAGACAGAAAACCTAAAGCAGAGGAGGATGAAATTTTGAACAGATCACCAAGAAAC
  AGAAAGCCACGAAGAGAGTGAAACAATCTTAAGAGCTTGATCTGTGATTTCTTCTCCCTC
  CTCCCCTGCAAGAGTGGTCCTAGGAGAGGACCTGGCACACCTTAGGTTGACATTCAGAAA
  ACTTCAAGACATCACCATCAGCAGGCTCCAGTTGAACACTAGTCTGTGTAACTTTAAACA
  TCTAGCAGTAAATACTTGCAGTTGTGATATAAAGGACCCTGTTTCTGTAGAAAAGAAAAC
  ATTTAACATAATGGTTGTGAAATGTAACATGAAGCAAACTAACTTTTTTTTTTTTAACAT
  CTTTGTTTTTAAAATAGAATGATAGAACTTTGCCAGTCTTTAAGATCTTGGCTTAATTTA
  ATGTATTAATCTGTTTGTGCAAACATAATACCACCATTTAAAAATGTTAGGGAGATGAGT
  TGCAGTTTTTATAATAGATTTTTTTTAAAGTTTGGTATTGTAAAACATTCACACCTCTGT
  CCCTCAAAATTGATAATTACGTTTAAAGTGCAGTCATTTGTGGTTAGAATCTTGTTTTGT
  TTGCTTCCATTATTGAGTTCCTCCTAAGGAAATTGAGGAGAGGGACTGAATAGAAGCCCA
  AATTCATATAAAAGTTGCGTTTAAGTTGTATTAAAAATAGATATATAAGAAAAAATTCTT
  TCACTTGATGTTTGTTAGACCAGAAAGTGTGTGTGTTCTGTAGCTCAGTTCCCAGACAGC
  TTTTTAGGTAGTGGAGGAGGTGGCTTCATGTGGCACTTGGGCATTTATATTCCACTTGGG
  AGGGTCAGGCTGTGGCCTTCTGGAGCAGGTGGCTTGTTAAGGAACGCTAGCAGGGCATGG
  CACGTGAGCTCCGGAATAGATGTCTTCATCACTTCTTCCACTGTGTGTTGACACTGTTTT
  CCTTACCTATTTCCTCAGATCCCCAGCTTTCTCCTCTGCTATGCATTTTCTTCACAGTGC
  AGCTTGCAGTCCGTTGCTGAAAATGATTATAAGCCCTGCATAATGTTAAGCTTTATTGTG
  ATTACGTGTATGTTTCTTCTTTCTTTTAAGCAGACCCATACCTTTCCAGGGTCAAAGTAC
  AGAATAGAATACATTGATACAAAGTACAGAAAAATACTTTGATTTTTATCCATTTCTTTT
  ACTCTGTGTAAAGACTTGAGAAGTCTAATTCACAGGCAAACCAATACAGAATTGACTGCA
  GTTGAACAGACTAGAAGTATTTGTGGGAGGAGTGACATGAAGCATGAGTTATCTGATTTT
  TTTTGTAGCTGCTATATATTTTAAGCCTTCATTTGCAATTCATGTAACAGTTGTGTCATA
  AATTACACAATAAAGCAGTCCTGTTCAAATTTTTTTTTAACGTGGCTTGTAGAATTTTTA
  AAAAAGTGATCTTAGGTTTGTTTTTTCATGCGGGATGCAGATGGGTGCTATCAGAGCCTC
  TCCCACACCACTATAGTGTAATAATGTTATTATTACTCTACACTGAAACGTATTCAGAGT
  TAGATATTATTTTAGCTTCAGTTGTTCTTTAGAGGCTTTCAAATGTACCGATGATACTGT
  TTCTTGCACTGAATATATAAACACTCCACAGTGTTTATATTGGGAAGATATTGGGAAGGA
  AATATATTTGTAAAAGATGAAGGCTGTATCTATTTTTTTTTCTTTTTAAAGTTTGTTCAC
  TTAAATTCTTTTGAGGATGGGATGTATTTTTCTTGCTGTTCAGTGCTTTTTCCTTTTCAT
  CTGTTGTTCTGTGGTCACAGTGACCTTAGCTACATAGCAGACTTTCCCAAATGTATTGAT
  TACAAATAAACAGTTGTTACTTAGCAAGACCTGAAAATATGTCTGCAGGTTTCTCCTTGA
  AGCAAATGTGTGGGATCATTGCATTTCCAGAAATCTGCCTCCTTCACCCTCCGTTGACAG
  TATATGTCATGCCTCACTTTCTTCTAGCTGAGCTTTAAATCATTAGAGCTTAAATTGTCA
  GATCGTTCATTGCCTTTCCAGGGTTATTTAGTAAAGTTTGTTGAAAACAAAAACGCCTTT
  TCTTGGTTCTTTTTTCAGTTATTTTGAAGGTCCAGCATCCTGATTAAATGTCTGACACAT
  TAATGAATGACCAGCAGCAGCTTTCAGCTCTTAAAAAGACACTTATATTTTGATTTTACA
  TGCTGGTTACCTGTTCCATTGTTGTCAAATGCCCACTCTCCATCAGATGTGTTCCTCCAT
  TTTCTTATCCACAAAGTACTCCTCACTTTTCAATTTGTCATGTTACTAAATGGTGTTACA
  TTAAAGCCCTGTGTTAAGTGTC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001746 unedited
  AACACTTAGGATTTTGTAACCGACTTCACTATAGGGCGGCCGCGCAATTCGCACGAGGGT
  CGGGCCGCCTCCGCCTCTCTCTTTACTGCGGCGCGGGGCAAGGTGTGCGGGCGGGAAGGG
  GCACGGGCACCCCCGCGGTCCTCGGGAGGCTAGAGATCATGGAAGGGAAGTGGTTGCTGT
  GTATGTTACTGGTGCTTGGAACTGCTATTGTTGAGGCTTATGATGGACATGATGATGATG
  TGATTGATATTGAGGATGACCTTGACGATGTCATTGAAGAGGTAGAAGACTCAAAACCAG
  ATACCACTGCTCCTCCTTCATCTCCCAAGGTTACTTACAAAGCTCCAGTTCCAACAGGGG
  AAGTATATTTTGCTGATTCTTTTGACAGAGGAACTCTGTCAGGGTGGATTTTATCCAAAG
  CCAAGAAAGACGATACCGATGATGAAATTGCCAAATATGATGGAAAGTGGGAGGTAGAGG
  AAATGAAGGAGTCAAAGCTTCCAGGTGATAAAGGACTTGTGTTGATGTCTCGGGCCAAGC
  ATCATGCCATCTCTGCTAAACTGAACAAGCCCTTCCTGTTTGACACCAAGCCTCTCATTG
  TTCAGTATGAGGTTAATTTCCAAAATGGAATAGAATGTGGTGGTGCCTATGTGAAACTGC
  TTTCTAAAACACCAGAACTCAACCTGGATCAGTTCCATNGACAGACCCCTTATACGATTA
  TGTTTGGTCCAGATNAATGTGGAGAGGACTATAAACTGCACTTCATCTTCCGACACANAA
  ACCCCAAAACGGGTATCTATGAAGAAAAACATNGCTAGAGGCCAGATGCAGATCTGAAGA
  CCTATTTTACTGATAAGAAACACATCCTTACCACTAATCTTGAATCAGAAATAGTTTTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001746 unedited
  CCCTTGCTCTGCNACCGCGGCCGCAATCTAANGATCGGTTTTTTTTTTTTTTTTTTGACA
  CTTAACACAGGNGCTTTAATGTAACACCATTTAGTAACATGACAAATTGAAAAGTGAGGA
  GTACTTTGTGGATAAGAAAATGGAGGAACACATCTGATGGAGAGTGGGCATTTGACAACA
  ATGGAACAGGTAACCAGCATGTAAAATCAAAATATAAGTGTCTTTTTAAGAGCTGAAAGC
  TGCTGCTGGTCATTCATTAATGTGTCAGACATTTAATCAGGATGCTGGACCTTCAAAATA
  ACTGAAAAAAGAACCAAGAAAAGGCGTTTTTGTTTTCAACAAACTTTACTAAATAACCCT
  GCAAAGGCAATGAACGATCTGACAATTTACACTCTAATGATTTAAAGCTCACCTAGAAGA
  AAGTGAGGCATGACATATACTGCCACCGGCAGGGCGACAGCGACGTCGATTTCTGGAAAT
  GCAACGATCCCACACATTTGTTTCAAGGACAACCCTGCACATATATTCTCAGGCCCTCGC
  TAACGCACACCTGCTTATTTGCGACCAACCACTCCGGCACCGCCCGCTCTGTACCTCACC
  GTACTGTGACCACCGAACCCCCTACGAACCGGCTCTCGCCCTGCTCCCCACGAAAAACAT
  CTCCCCTCCCCCAAAGAATCTATCCGAACAACCTTTTCAACGAAACAAACTCTCCTTCCC
  GCCTTATTTTTTACACACATATTCCCTTCCCCAACCTTTTCCCAACTAAACCTTGNGGGC
  GGCTTACTATCTTCCCCCCACGAACCCGCTTTCCTCGTCTCCCTCTGAAAGCCCCTCTAC
  GCACACCTTGCCCCTTACCCAATCACCTCAACCCCCGATACGTTCAATTGGTTTATACCA
  CCTTCCTCCTTTATTTTCTTCGCCGT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001746
• Insert Size: 4700 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001746.3, NP_001737.1
• RefSeq Size: 4953 bp
• RefSeq ORF: 1779 bp
• Locus ID: 821
• Cytogenetics: 5q35.3
• Domains: calreticulin
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Antigen processing and presentation
• Gene Summary: 'This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2018]'
  Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.