DNA Polymerase epsilon (POLE3) (NM_017443) Human Untagged Clone

CAT#: SC108364

POLE3 (untagged)-Human polymerase (DNA directed), epsilon 3 (p17 subunit) (POLE3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: POLE3
• Synonyms: CHARAC17; CHRAC2; CHRAC17; p17; YBL1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC108364 sequence for NM_017443 edited (data generated by NextGen Sequencing)
  ATGGCGGAGAGGCCCGAGGACCTAAACCTGCCCAATGCCGTGATCACCAGGATCATCAAG
  GAGGCGCTCCCGGACGGTGTCAACATCTCCAAGGAGGCCCGGAGCGCCATCTCCCGCGCC
  GCCAGCGTCTTCGTGCTGTACGCCACATCCTGTGCTAACAACTTTGCAATGAAAGGAAAG
  CGGAAGACGCTGAATGCCAGTGATGTGCTCTCAGCCATGGAAGAGATGGAGTTCCAGCGG
  TTCGTTACCCCATTGAAAGAAGCTCTGGAAGCATATAGGCGGGAGCAGAAAGGCAAGAAG
  GAGGCCTCAGAGCAAAAGAAGAAGGACAAAGACAAAAAAACAGACTCGGAAGAGCAAGAC
  AAGAGCAGGGATGAGGACAATGATGAAGACGAAGAAAGGCTGGAAGAAGAAGAACAGAAT
  GAAGAGGAAGAAGTAGACAACTGA
  
  Clone variation with respect to NM_017443.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_017443 unedited
  TTGTCCTACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCTGAAGCGGAGGCGA
  AGGGGAGTTTAAGCCCCAGCGGCGGCAATGGCGGAGAGGCCCGAGGACCTAAACCTGCCC
  AATGCCGTGATCACCAGGATCATCAAGGAGGCGCTCCCGGACGGTGTCAACATCTCCAAG
  GAGGCCCGGAGCGCCATCTCCCGCGCCGCCAGCGTCTTCGTGCTGTACGCCACATCCTGT
  GCTAACAACTTTGCAATGAAAGGAAAGCGGAAGACGCTGAATGCCAGTGATGTGCTCTCA
  GCCATGGAAGAGATGGAGTTCCAGCGGTTCGTTACCCCATTGAAAGAAGCTCTGGAAGCA
  TATAGGCGGGAGCAGAAAGGCAAGAAGGAGGCCTCAGAGCAAAAGAAGAAGGACAAAGAC
  AAAAAAACAGACTCGGAAGAGCAAGACAAGAGCAGGGATGAGGACAATGATGAAGACGAA
  GAAAGGCTGGAAGAAGAAGAACAGAATGAAGAGGAAGAAGTAGACAACTGAAAAGGGCGG
  GAGACTGTGGCACCTTGGAAGGTACCACTTGAAATGAGACGTGCTACGTGTTTCTGTGAA
  GCTTTTCCATGCTGGGCAGAGTAGTCTCAAGCAAAAGTGCCTGAAAAGATCAGAATAAAA
  ACTGACTAGAAATACCGTCAAAACCAGCACTTACCAAACTCAGAGCATCTGAGTAGCAGA
  ATCCTGTTTTGCTTCATCAATCCTGAAGTTATGGCCTTNTGACAGAAGGGATTCTGAACG
  ACTAAATTAGTCAGTTTGCTCGCTTTTGTTTACTTNAAAGTATGGNTAGAAGGGTTTTTG
  ATCTGAAGTCCTCCCTAGTCCCCCAAATAGTATAATAACTCCATGCTGCCTGTGTGGTCC
  AAANACAGAGCAGCCAAGCTAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_017443 unedited
  CGAGGCCGCAATTTATATCGAGTTTTTTTTTTTTTTTTTTAACAAAACTTTTATTTGTAC
  AAAGCATTACAATCTTCTCAGCATTCTTCACTCACAAACTTTTCACTGTATTTAACAAGT
  TAACAGTGTCAAACTACACGTCACTACCTGTCAAACCCCAAGCACTCAACTTAGAAACAA
  AAAGCGCTTGGAGCACTGAATGGAAACAGAAAAAGGCTAAGAAAGGCCAACAGAGATATT
  TTAGAAGCAGTTAAAGAGGATGGTTTAGGGAGAGTTAGATTCCTGAGCACCATCAGATTT
  CCCTTAAGGTTTTTTGCGAAGGGGCTCCACAAAATAATTTTTAGAAGACATGAGACAAAA
  TTAGCCAGGCTTGGTGGCACGCATCTGTAGACCCAGATACTCAGGAGGCTCAGGCGGGAG
  GATCACCTGAGCCCAGGATTTCAAGGATGCAATGAGCTATGATCATGCCACTGCACTCCA
  GCCTGGGCCACAGAGTGAGAGACTCCATCTGCTTAAAACAAAACGTGAGATTATAACTAA
  CGAATTAAGAGATCAGAGGAACTCACACTTTGGAGTATTAAGCAGGCTATTAAAGCTTAC
  AGACTGACCGAAGTGAGAAAAGGAGGCGCATGACAAAAGCGCGATGGGGCACTACAAGAC
  ACGCCCGGAGAACAGAAACGACCCCAGCCGGCTCTCAAGGGCGAAAACTCGCCGCGTAAA
  GAAACATCAAGATTCGCCCCTCCCTTCGTGACTTGTCCGAATGTACAAGCCCCTACCCGC
  CTACACTTGCGACGACCCACCTAACTAACACGAGGCAACCGCTGGGTGCTTCTACCCCCT
  TACCGCTAGGGGGTAGACAAATTACTCAAAGCTGCCCCAACACACGATAAAATAAGGCGC
  ACCCTGGCACCTATAGTACTAGTGATATTTGGATAAACAAACTTGCCGACATTGTCGTGG
  CCTTACACACCTACGCCCATGGCCGGAATAGAAGAACAATGGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_017443
• ORF Size: 444 bp
• Insert Size: 2220
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_017443.3, NP_059139.2
• RefSeq Size: 2185
• RefSeq ORF: 444
• Locus ID: 54107
• Domains: CBFD_NFYB_HMF
• Protein Pathways: Base excision repair, DNA replication, Metabolic pathways, Nucleotide excision repair, Purine metabolism, Pyrimidine metabolism
• Gene Summary: POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging. [supplied by OMIM, Apr 2004]
  Transcript Variant: This variant (1) represents the longer protein-coding transcript. Variants 1 and 2 both encode the same protein.