RIP (RIPK1) (NM_003804) Human Untagged Clone

CAT#: SC108466

RIPK1 (untagged)-Human receptor (TNFRSF)-interacting serine-threonine kinase 1 (RIPK1)


  "NM_003804" in other vectors (7)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol RIPK1
Synonyms IMD57; RIP; RIP-1; RIP1
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF sequence for NM_003804 edited
ATGCAACCAGACATGTCCTTGAATGTCATTAAGATGAAATCCAGTGACTTCCTGGAGAGT
GCAGAACTGGACAGCGGAGGCTTCGGGAAGGTGTCTCTGTGTTTCCACAGAACCCAGGGA
CTCATGATCATGAAAACAGTGTACAAGGGGCCCAACTGCATTGAGCACAACGAGGCCCTC
TTGGAGGAGGCGAAGATGATGAACAGACTGAGACACAGCCGGGTGGTGAAGCTCCTGGGC
GTCATCATAGAGGAAGGGAAGTACTCCCTGGTGATGGAGTACATGGAGAAGGGCAACCTG
ATGCACGTGCTGAAAGCCGAGATGAGTACTCCGCTTTCTGTAAAAGGAAGGATAATTTTG
GAAATCATTGAAGGAATGTGCTACTTACATGGAAAAGGCGTGATACACAAGGACCTGAAG
CCTGAAAATATCCTTGTTGATAATGACTTCCACATTAAGATCGCAGACCTCGGCCTTGCC
TCCTTTAAGATGTGGAGCAAACTGAATAATGAAGAGCACAATGAGCTGAGGGAAGTGGAC
GGCACCGCTAAGAAGAATGGCGGCACCCTCTACTACATGGCGCCCGAGCACCTGAATGAC
GTCAACGCAAAGCCCACAGAGAAGTCGGATGTGTACAGCTTTGCTGTAGTACTCTGGGCG
ATATTTGCAAATAAGGAGCCATATGAAAATGCTATCTGTGAGCAGCAGTTGATAATGTGC
ATAAAATCTGGGAACAGGCCAGATGTGGATGACATCACTGAGTACTGCCCAAGAGAAATT
ATCAGTCTCATGAAGCTCTGCTGGGAAGCGAATCCGGAAGCTCGGCCGACATTTCCTGGC
ATTGAAGAAAAATTTAGGCCTTTTTATTTAAGTCAATTAGAAGAAAGTGTAGAAGAGGAC
GTGAAGAGTTTAAAGAAAGAGTATTCAAACGAAAATGCAGTTGTGAAGAGAATGCAGTCT
CTTCAACTTGATTGTGTGGCAGTACCTTCAAGCCGGTCAAATTCAGCCACAGAACAGCCT
GGTTCACTGCACAGTTCCCAGGGACTTGGGATGGGTCCTGTGGAGGAGTCCTGGTTTGCT
CCTTCCCTGGAGCACCCACAAGAAGAGAATGAGCCCAGCCTGCAGAGTAAACTCCAAGAC
GAAGCCAACTACCATCTTTATGGCAGCCGCATGGACAGGCAGACGAAACAGCAGCCCAGA
CAGAATGTGGCTTACAACAGAGAGGAGGAAAGGAGACGCAGGGTCTCCCATGACCCTTTT
GCACAGCAAAGACCTTACGAGAATTTTCAGAATACAGAGGGAAAAGGCACTGCTTATTCC
AGTGCAGCCAGTCATGGTAATGCAGTGCACCAGCCCTCAGGGCTCACCAGCCAACCTCAA
GTACTGTATCAGAACAATGGATTATATAGCTCACATGGCTTTGGAACAAGACCACTGGAT
CCAGGAACAGCAGGTCCCAGAGTTTGGTACAGGCCAATTCCAAGTCATATGCCTAGTCTG
CATAATATCCCAGTGCCTGAGACCAACTATCTAGGAAATACACCCACCATGCCATTCAGC
TCCTTGCCACCAACAGATGAATCTATAAAATATACCATATACAATAGTACTGGCATTCAG
ATTGGAGCCTACAATTATATGGAGATTGGTGGGACGAGTTCATCACTACTAGACAGCACA
AATACGAACTTCAAAGAAGAGCCAGCTGCTAAGTACCAAGCTATCTTTGATAATACCACT
AGTCTGACGGATAAACACCTGGACCCAATCAGGGAAAATCTGGGAAAGCACTGGAAAAAC
TGTGCCCGTAAACTGGGCTTCACACAGTCTCAGATTGATGAAATTGACCATGACTATGAG
CGAGATGGACTGAAAGAAAAGGTTTACCAGATGCTCCAAAAGTGGGTGATGAGGGAAGGC
ATAAAGGGAGCCACGGTGGGGAAGCTGGCCCAGGCGCTCCACCAGTGTTCCAGGATCGAC
CTTCTGAGCAGCTTGATTTACGTCAGCCAGAACTAA
>OriGene 5' read for NM_003804 unedited
CAGTATTTTGTAATACGACTCACTTATAGGGCGGCCGCGAATTCGCACGAGGGCGTTCTT
GAGCTTCAGAATGCAACCAGACTGTCCTTGAATGTCATTAAGATGAAATCCAGTGACTTC
CTGGAGAGTGCAGAACTGGACAGCGGAGGCTTCGGGAAGGTGTCTCTGTGTTTCCACAGA
ACCCAGGGACTCATGATCATGAAAACAGTGTACAAGGGGCCCAACTGCATTGAGCACAAC
GAGGCCCTCTTGGAGGAGGCGAAGATGATGAACAGACTGAGACACAGCCGGGTGGTGAAG
CTCCTGGGCGTCATCATAGAGGAAGGGAAGTACTCCCTGGTGATGGAGTACATGGAGAAG
GGCAACCTGATGCACGTGCTGAAAGCCGAGATGAGTACTCCGCTTTCTGTAAAAGGAAGG
ATAATTTTGGAAATCATTGAAGGAATGTGCTACTTACATGGAAAAGGCGTGATACACAAG
GACCTGAAGCCTGAAAATATCCTTGTTGATAATGACTTCCACATTAAGATCGCAGACCTC
GGCCTTGCCTCCTTTAAGATGTGGAGCAAACTGAATAATGAAGAGCACAATGAGCTGAGG
GAAGTGGACGGCACCGCTAAGAAGAATGGCGGCACCCTCTACTACATGGCGCCCGAGCAC
CTGAATGACGTCAACGCAAAGCCCACAGAGAAGTCGGATGTGTACAGCTTTGCTGTAGTA
CTCTGGGCGATATTTGCAAATAAGGAGCCCATATGAAATGCTATCTGTGAGCAGCAGTTG
ATAATGTGCATAAAATCTGGGAACAGGCCAGATGTGGATGACATCACTGAGTACTGCCCA
AGAGA
>OriGene 3' read for NM_003804 unedited
TCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTGGGGGATAAATTTTTATTTTAAAAA
GTGTTAAAAAATGCCTTGCCCTCTTGCCTTTGAACATTAATTATTCAACCTCTTTGGAAT
CTAAGAGATTTGATAACACCATTTGGATGGTGGTACAAGGAGCAAACAGAACTCACCCAG
GCCCCTCCAGCAAAGCCTGGAGCCTCCCTCCATTCTCCCTTTTGGGCTGTAGGAGCCAAG
GCTGCGTGGTGGCCAAGTAGTAACCGGACAGGTGCAGACAGGAGAGCCGAGGCTCATTAC
TTTACAGCAGTGCTCTTCTCAACCGGGGCAATTTTCCCCTTTCCTTGGACCATTTGACAA
TGTTTAGAGACTATTGTCACAACTGGGGCGGGGGGCTGGGGAGAACAGTGCCCCTGGCAT
CTAGTAGGTGGGGGCAGGGATGCTACTAAACATCCTACAAGGAACAGGACAGTCCCCACA
ACAGAATTACCCCAGCCCGAGATGCCGACAGTGGCAAGGCTGAGACAGCCTGCTCTGCAC
CCCATTTCAGGGGTGTGTATGTGTCTGCTAGAGTTGAGGGGATTTACAATCAGAATCAAC
CACACTGTTATCAGCCCAAGAACCAGAATCTGTCCGACAGCCAGATTGCCATTACACACC
CTTTTTGGCCTCCCTCTGGGGAGAGCTAGCACAAAGCCTTCCTTTGTCCGTTTACAAAAT
GCCAGTGACACTGAGCGGGCTACCCAGCTTAAGCTTTTATATTAGTCTTTAATCCCCCCC
AAGTTTAAGTGGCCTTTGAAGGCTGGTGCTAAAGCCCAATACCCACTTAGAGCTGCCTTT
TTACTTTGTCCCCAGAAAAATTGAAAATCTTTCAGTCCCCGATTAACCGAGGAACCCTTA
ACAGTTAACCCTTGGGTTCTGGCTACCCAAGTAAAAAAAAATTTCTGTTCTTCCAAGCCC
TACGCTGGGAGGCCAAATGCCGAAAACTTTAAGTATCAGATTTTGTGACCACGTAAC
Restriction Sites NotI-NotI     
ACCN NM_003804
ORF Size 2016 bp
Insert Size 3900
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_003804.3, NP_003795.2
RefSeq Size 3864
RefSeq ORF 2016
Locus ID 8737
Domains DEATH, pkinase, TyrKc, S_TKc
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Apoptosis, Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway
Gene Summary This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth. [provided by RefSeq, Aug 2017]
Transcript Variant: This variant (1) represents the shorter transcript and encodes the longer isoform (1).

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