NR2C1 (NM_003297) Human Untagged Clone

CAT#: SC108472

NR2C1 (untagged)-Human nuclear receptor subfamily 2, group C, member 1 (NR2C1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NR2C1
• Synonyms: TR2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_003297 edited
  ATGGCAACCATAGAAGAAATTGCACATCAAATTATTGAACAACAGATGGGAGAGATTGTT
  ACAGAGCAGCAAACTGGGCAGAAAATCCAGATTGTGACAGCACTTGATCATAATACCCAA
  GGCAAGCAGTTCATTCTGACAAATCACGACGGCTCTACTCCAAGCAAAGTCATTCTGGCC
  AGGCAAGATTCCACTCCGGGAAAAGTTTTCCTTACAACTCCAGATGCAGCAGGTGTCAAC
  CAGTTATTTTTTACCACTCCTGATCTGTCTGCACAACACCTGCAGCTCCTAACAGATAAT
  TCTCCAGACCAAGGACCAAATAAGGTTTTTGATCTTTGCGTAGTATGTGGAGACAAAGCA
  TCAGGACGTCATTATGGAGCAGTAACTTGTGAAGGCTGCAAAGGATTTTTTAAAAGAAGC
  ATCCGAAAAAATTTAGTATATTCATGTCGAGGATCAAAGGATTGTATTATTAATAAGCAC
  CACCGAAACCGCTGTCAATACTGCAGGTTACAGAGATGTATTGCGTTTGGAATGAAGCAA
  GACTCTGTCCAATGTGAAAGAAAACCCATTGAAGTATCACGAGAAAAATCTTCCAACTGT
  GCCGCTTCAACAGAAAAAATCTATATCCGAAAGGACCTTCGTAGCCCATTAACTGCAACT
  CCAACTTTTGTAACAGATAGTGAAAGTACAAGGTCAACAGGACTGTTAGATTCAGGAATG
  TTCATGAATATTCATCCATCTGGAGTAAAAACTGAGTCAGCTGTGCTGATGACATCAGAT
  AAGGCTGAATCATGTCAGGGAGATTTAAGTACATTGGCCAATGTGGTTACATCATTAGCG
  AATCTTGGAAAAACTAAAGATCTTTCTCAAAATAGTAATGAAATGTCTATGATTGAAAGC
  TTAAGCAATGATGATACCTCTTTGTGTGAATTTCAAGAAATGCAGACCAACGGTGATGTT
  TCAAGGGCATTTGACACTCTTGCAAAAGCATTGAATCCTGGAGAGAGCACAGCCTGCCAG
  AGCTCAGTAGCGGGCATGGAAGGAAGTGTACACCTAATCACTGGAGATTCAAGCATAAAT
  TACACCGAAAAAGAGGGGCCACTTCTCAGCGATTCACATGTAGCTTTCAGGCTCACCATG
  CCTTCTCCTATGCCTGAGTACCTGAATGTGCACTACATTGGGGAGTCTGCCTCCAGACTG
  CTGTTCTTATCAATGCACTGGGCACTTTCGATTCCTTCTTTCCAGGCTCTAGGGCAAGAA
  AACAGCATATCACTGGTGAAAGCTTACTGGAATGAACTTTTTACTCTTGGTCTTGCCCAG
  TGCTGGCAAGTGATGAATGTAGCAACTATATTAGCAACATTTGTCAATTGTCTTCACAAT
  AGTCTTCAACAAGATAAAATGTCAACAGAAAGAAGAAAATTATTGATGGAGCACATCTTC
  AAACTACAGGAGTTTTGTAACAGCATGGTTAAACTCTGCATTGATGGATACGAATATGCC
  TACCTGAAGGCAATAGTACTCTTCAGTCCAGATCATCCAAGCCTAGAAAACATGGAACAG
  ATAGAGAAATTTCAGGAAAAGGCTTATGTGGAATTCCAAGATTATATAACCAAAACATAT
  CCAGATGACACCTACAGGTTATCCAGACTACTACTCAGATTGCCAGCTTTAAGACTGATG
  AATGCTACCATCACTGAAGAATTGTTTTTCAAAGGTCTCATTGGCAATATACGAATTGAC
  AGTGTTATCCCACATATTTTGAAAATGGAGCCTGCAGATTATAACTCTCAAATAATTGGT
  CACAGCATTTGA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003297
• Insert Size: 4180 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: The ORF of this clone has been fully sequenced and found to contain one SNP when compared with NM_003297.1.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_003297.1, NP_003288.1
• RefSeq Size: 2202 bp
• RefSeq ORF: 1812 bp
• Locus ID: 7181
• Cytogenetics: 12q22
• Domains: HOLI, zf-C4
• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
• Gene Summary: 'This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a, also known as TR2-11). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.