Tripeptidyl peptidase II (TPP2) (NM_003291) Human Untagged Clone

CAT#: SC108509

TPP2 (untagged)-Human tripeptidyl peptidase II (TPP2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TPP2
• Synonyms: TPP-2; TPP-II; TPPII
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC108509 sequence for NM_003291 edited (data generated by NextGen Sequencing)
  ATGGCCACCGCTGCGACTGAGGAGCCCTTCCCTTTTCACGGTCTCCTGCCGAAGAAGGAG
  ACCGGAGCCGCCTCCTTCCTCTGCCGCTACCCGGAGTATGATGGGCGGGGGGTGCTCATC
  GCAGTCCTGGACACGGGGGTCGACCCGGGGGCTCCGGGCATGCAGGTTACAACTGATGGA
  AAACCAAAAATCGTTGATATCATTGATACAACAGGAAGTGGCGATGTGAATACTGCTACA
  GAAGTAGAGCCAAAGGATGGTGAGATTGTTGGCCTTTCAGGAAGAGTGCTTAAGATTCCT
  GCAAGCTGGACAAATCCCTCAGGCAAATATCATATTGGCATAAAAAATGGCTATGACTTC
  TATCCTAAGGCACTCAAGGAAAGGATACAGAAAGAACGGAAGGAAAAAATCTGGGACCCT
  GTTCACAGAGTGGCCCTTGCAGAAGCCTGTAGAAAACAGGAAGAATTTGATGTTGCCAAC
  AACGGCTCTTCTCAAGCAAATAAACTAATCAAGGAGGAACTTCAAAGTCAAGTGGAATTG
  CTAAATTCTTTTGAGAAGAAATACAGCGATCCTGGCCCTGTATATGACTGCTTGGTATGG
  CATGATGGCGAAGTCTGGAGAGCCTGCATTGATTCTAATGAAGATGGGGACTTGAGTAAA
  TCTACCGTGTTGAGAAACTACAAAGAAGCCCAAGAATATGGCTCTTTTGGCACAGCTGAG
  ATGTTGAATTACTCCGTTAATATATACGATGATGGAAACCTGCTCTCCATTGTGACCAGT
  GGAGGAGCTCATGGGACACATGTAGCTAGTATAGCTGCTGGACACTTTCCAGAAGAACCT
  GAACGGAATGGGGTAGCTCCTGGTGCTCAAATTCTTTCCATCAAGATTGGTGATACAAGA
  CTAAGCACAATGGAAACAGGCACAGGCCTCATAAGAGCTATGATAGAAGTTATAAATCAT
  AAGTGTGATCTTGTCAACTACAGTTACGGAGAAGCAACTCACTGGCCAAATTCTGGGAGA
  ATTTGTGAAGTAATTAATGAAGCAGTATGGAAGCATAATATAATTTATGTTTCAAGTGCT
  GGAAATAATGGTCCATGCCTGTCTACAGTTGGTTGTCCAGGTGGAACTACATCAAGTGTG
  ATAGGTGTTGGTGCTTATGTTTCTCCTGATATGATGGTTGCTGAGTATTCACTGAGAGAG
  AAATTACCTGCAAATCAATATACTTGGTCTTCTAGAGGACCTAGTGCTGACGGGGCCCTT
  GGTGTGAGTATCAGTGCGCCAGGAGGAGCCATTGCTTCTGTTCCTAACTGGACACTGAGA
  GGGACGCAGCTGATGAATGGAACATCTATGTCTTCCCCCAATGCATGTGGAGGCATTGCC
  CTGATCCTTTCAGGTCTGAAAGCTAATAACATTGACTACACAGTTCATTCAGTCAGAAGA
  GCTCTAGAAAACACTGCAGTGAAGGCTGACAATATAGAAGTATTTGCTCAAGGACATGGT
  ATTATTCAGGTTGATAAAGCCTATGACTACCTCGTTCAGAATACATCATTTGCTAATAAA
  TTAGGTTTTACTGTTACTGTTGGAAATAACCGTGGCATCTACCTCCGAGATCCTGTTCAG
  GTGGCTGCACCTTCAGATCATGGCGTTGGCATTGAACCTGTATTTCCGGAGAACACAGAA
  AACTCTGAAAAAATATCCCTTCAGCTTCATTTAGCTCTGACTTCAAATTCATCTTGGGTT
  CAGTGTCCCAGCCATTTGGAACTCATGAATCAATGTAGACACATAAACATACGTGTGGAT
  CCCAGGGGCTTAAGAGAAGGATTGCATTATACAGAGGTATGTGGCTATGATATAGCATCC
  CCTAACGCAGGTCCGCTCTTCAGAGTTCCGATCACTGCAGTTATAGCAGCAAAAGTAAAT
  GAATCATCACATTATGATCTAGCCTTTACAGATGTACACTTTAAACCTGGTCAAATTCGA
  AGGCATTTTATTGAGGTTCCTGAGGGTGCAACATGGGCTGAAGTGACAGTGTGTTCGTGT
  TCTTCTGAGGTGTCAGCAAAGTTTGTTCTACATGCAGTCCAGCTTGTGAAGCAAAGAGCA
  TATCGAAGCCATGAATTCTATAAGTTTTGTTCTCTTCCAGAGAAAGGAACACTGACTGAA
  GCTTTTCCTGTCCTAGGTGGAAAAGCAATTGAATTTTGCATTGCTCGTTGGTGGGCAAGT
  CTCAGTGATGTCAACATTGATTATACCATTTCTTTCCATGGGATAGTGTGTACTGCTCCT
  CAGTTAAACATTCATGCATCGGAAGGAATCAACCGCTTTGATGTTCAGTCCTCCTTGAAA
  TACGAAGATCTGGCTCCCTGCATAACTTTGAAGAACTGGGTCCAAACACTGCGCCCAGTG
  AGTGCAAAAACAAAACCTTTAGGATCAAGAGATGTTTTGCCAAATAACCGTCAACTTTAT
  GAGATGGTCCTGACATATAACTTTCATCAACCCAAGAGTGGGGAAGTAACTCCAAGCTGC
  CCACTACTTTGTGAACTATTATATGAATCTGAATTTGACAGCCAACTGTGGATTATTTTT
  GACCAGAACAAAAGACAGATGGGTTCAGGCGATGCCTATCCACATCAGTATTCTTTGAAA
  CTGGAGAAAGGAGATTATACAATTCGACTACAGATTCGCCATGAGCAAATCAGTGATTTG
  GAACGCCTTAAAGACCTTCCATTTATTGTTTCTCATAGATTGTCTAATACCTTGAGCTTA
  GATATTCATGAAAATCATAGTTTTGCACTTCTAGGGAAGAAGAAATCAAGCAATTTGACA
  TTACCACCCAAATATAACCAGCCATTCTTTGTTACTTCCTTACCTGATGATAAAATACCT
  AAAGGGGCAGGACCTGGATGCTATCTTGCAGGATCCTTAACATTGTCAAAGACTGAACTA
  GGAAAGAAAGCTGATGTAATCCCTGTTCATTACTACTTAATACCTCCACCAACAAAGACT
  AAGAATGGCAGCAAAGATAAGGAAAAAGATTCAGAAAAAGAGAAAGATTTAAAAGAAGAG
  TTTACTGAAGCATTACGAGATCTTAAAATTCAGTGGATGACAAAGCTGGATTCTAGTGAC
  ATTTATAACGAATTGAAAGAAACATATCCTAATTATCTTCCTCTGTACGTTGCACGACTT
  CATCAATTGGATGCTGAAAAGGAACGAATGAAAAGACTTAATGAAATTGTTGATGCGGCA
  AATGCTGTTATTTCTCATATAGATCAAACAGCCCTAGCAGTTTATATTGCAATGAAGACT
  GATCCCAGGCCTGATGCAGCTACTATAAAAAATGACATGGACAAACAAAAATCCACCCTC
  GTAGATGCCCTTTGTAGGAAAGGTTGTGCCCTGGCAGACCATCTTCTTCACACCCAGGCT
  CAAGACGGAGCCATTTCCACTGATGCAGAAGGAAAGGAGGAGGAAGGAGAAAGTCCTTTG
  GATTCTCTGGCAGAAACATTTTGGGAAACTACTAAATGGACTGATCTCTTTGACAATAAG
  GTTTTGACATTTGCATATAAACATGCATTAGTAAATAAAATGTATGGGAGAGGCCTTAAA
  TTTGCAACTAAACTTGTGGAAGAAAAACCAACAAAAGAAAACTGGAAAAATTGTATTCAA
  CTGATGAAGTTACTTGGATGGACCCATTGTGCATCTTTTACTGAAAACTGGCTCCCCATC
  ATGTATCCTCCCGATTATTGCGTATTCTAA
  
  Clone variation with respect to NM_003291.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003291 unedited
  GTTTTTNGGNAATTATGTNAATACGCACTTCACTNTAAGGGNCGCGCCGCGNAATTCGGC
  ACCAGCCATGGCCACCGCTGCGACTGAGGAGCCCTTCCCTTTTCACGGTCTCCTGGCGAA
  GAAGGAGACCGGAGCCGCCTCCTTCCTCTGCCGCTACCCGGAGCATGATGGGCGGGGGGC
  GCTCATCGCAGTCCTGGACACGGGGGTCGACCCGGGCGCTCCGGGCATGCAGGCTACAAC
  TGATGGAAAACCAAAAATCGCCGATATCATTGATACAACAGGAAGCGGCGATGCGAATAC
  TGCTACAGAAGTATAGCCAAAGGATGGTGAGATTGTTGGCCTTTCAGGAAGAGTGCTTAA
  GATTCCTGCAAGCTGGACAAATCCCTCAGGCAAATATCATATTGCCATAAAAAATGGCTA
  TGACTTCTATCCTAAGGCACTCAAGGAAAGGATACAGAAAGAACGGAAGGAAAAAACCTG
  GGACCCTGTTCACCAGAGTGGCCCTTGCACAAGCCTGTAGAAAACAGGAAGAATTCGATG
  CTGCCAACAACCGGCTCTTCTCAAGCCACTAAACTAACCCCGGAGGAACTTCAAAGCCAA
  GTGGAACTGCTAAATTCTTTTGAGAAGAAATACAGCGATCCTGGCCCTGTATATGACTGC
  TTGGCATGGCATGACGGCGAAGTCTGCAGAGCCTTGCTTGTATCTAATGAAGATGGGCAC
  TTGAGTAAACCTACCGTGTTGACGAACCACCCAAGAGCCCAAGTATATCGGCTCTTTTTG
  TCACAGTTGAAATGGTGAATTACTCCGCTCATATATACGATGATCGTAACCCTGCTCTCC
  ATTGCGACCAACGCGAGGAGCCTATGCCACCCTCGCACTCACTATAGCCTGCTCGACACT
  TCCCACACAACCTGAACGAAATGCGGGACCTCCTGCGCCCAATTCTTTCATCAAAATCGT
  GA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003291 unedited
  NCCTATATATGANACCGCGGCCGCAATCTAGNATCGAGTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAAAAAACAGGGCTTTTTAAAAACCAGCCCG
  GGATAGGGGAGGAAAACATGCTTTAAACTAAAAAGGCCACAAATTTGTTTTTATCCCCAT
  TCACTATAAAACTTCCTTTTTTAAAATTAAAAGGCTGGTTCCCTTTTTTAAAATCCCCAA
  TAATCGGGGGGATCCATGAGGGGGACCCATTTTTAAATAAAAAATGCCCAAGGGGCCCAT
  CCAAGAAACTTCATAAGTGGAATACAATTTTCCCAGTTTTTTTTGGGGGGGTTTTCTTCC
  ACAAGTTAAGTGGCAATTTTAAGGCCCCCCCCCTCCATTTTTTTAACTAAGGCATGGTTA
  TACGCAAAGGTACAAACCTTTTTGGCCAAGAAATACCCCCCTTGACGAGTCCCCCCAAAG
  GTGTCGTGCAAAAAATCACAAGGCCCTTTTCCTCCTCCCCGTTTTTCTCTTGCATAGCGG
  GAACGGGCTCCCCCTTAGCCCGCGGCTGCTAAAAATACGGCCTCACTTCGCACCCTCCCT
  TCCAGCAGGGAGCATCACTCGAGGCGGTCTTATGAGTATCGCGATATTCGTCTCTCCTCA
  TGTCTCACCTCCTCGCTCCCGCCCTCCTTGCACCTCTTAGGTCGCCGCCCCTCTCCCATA
  TTCGTACCGAACCCGCTCGGTGCGTCGAGCTCTCCGATCCCCGCGCTCGCTGCGAGCTCC
  CTCACCCGTACCGCGTATCTCCGCCGTTTCCGCTCTAGCCCGGCCCCTCGCGACCCAAAC
  TGCACACCGTCCGCCCCTCTCACCACATCTTTCCTCTTCTCGCCAGACCTATACGATTTA
  CCTGTACTTTATATATCCGCGCCACCGATTCCCACCCCCCTACCG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003291
• Insert Size: 4100 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_003291.1, NP_003282.1
• RefSeq Size: 4626 bp
• RefSeq ORF: 3750 bp
• Locus ID: 7174
• Cytogenetics: 13q33.1
• Domains: Peptidase_S8
• Protein Families: Druggable Genome, Protease
• Gene Summary: 'This gene encodes a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase; the amino acid sequence surrounding the serine residue at the active site is similar to the peptidases of the subtilisin class rather than the trypsin class. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) represents the shortest transcript and encodes the shortest, but most predominant, isoform (1).