LILRB3 (NM_006864) Human Untagged Clone

CAT#: SC108531

LILRB3 (untagged)-Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 (LILRB3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LILRB3
• Synonyms: CD85A; HL9; ILT-5; ILT5; LILRA6; LIR-3; LIR3; PIR-B; PIRB
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006864 edited
  GAATTCGGCACGAGGCTGGGGCCCCTGGGAGGAGACGCCATGATCCCCACCTTCACGGCT
  CTGCTCTGCCTCGGGCTGAGTCTGGGCCCCAGGACCCACATGCAGGCAGGGCCCCTCCCC
  AAACCCACCCTCTGGGCTGAGCCAGGCTCTGTGATCAGCTGGGGGAACTCTGTGACCATC
  TGGTGTCAGGGGACCCTGGAGGCTCGGGAGTACCGTCTGGATAAAGAGGAAAGCCCAGCA
  CCCTGGGACAGACAGAACCCACTGGAGCCCAAGAACAAGGCCAGATTCTCCATCCCATCC
  ATGACAGAGGACTATGCAGGGAGATACCGCTGTTACTATCGCAGCCCTGTAGGCTGGTCA
  CAGCCCAGTGACCCCCTGGAGCTGGTGATGACAGGAGCCTACAGTAAACCCACCCTTTCA
  GCCCTGCCGAGTCCTCTTGTGACCTCAGGAAAGAGCGTGACCCTGCTGTGTCAGTCACGG
  AGCCCAATGGACACTTTCCTTCTGATCAAGGAGCGGGCAGCCCATCCCCTACTGCATCTG
  AGATCAGAGCACGGAGCTCAGCAGCACCAGGCTGAATTCCCCATGAGTCCTGTGACCTCA
  GTGCACGGGGGGACCTACAGGTGCTTCAGCTCACACGGCTTCTCCCACTACCTGCTGTCA
  CACCCCAGTGACCCCCTGGAGCTCATAGTCTCAGGATCCTTGGAGGGTCCCAGGCCCTCA
  CCCACAAGGTCCGTCTCAACAGCTGCAGGCCCTGAGGACCAGCCCCTCATGCCTACAGGG
  TCAGTCCCCCACAGTGGTCTGAGAAGGCACTGGGAGGTACTGATCGGGGTCTTGGTGGTC
  TCCATCCTGCTTCTCTCCCTCCTCCTCTTCCTCCTCCTCCAACACTGGCGTCAGGGAAAA
  CACAGGACATTGGCCCAGAGACAGGCTGATTTCCAACGTCCTCCAGGGGCTGCCGAGCCA
  GAGCCCAAGGACGGGGGCCTACAGAGGAGGTCCAGCCCAGCTGCTGACGTCCAGGGAGAA
  AACTTCTGTGCTGCCGTGAAGAACACACAGCCTGAGGACGGGGTGGAAATGGACACTCGG
  AGCCCACACGATGAAGACCCCCAGGCAGTGACGTATGCCAAGGTGAAACACTCCAGACCT
  AGGAGAGAAATGGCCTCTCCTCCCTCCCCACTGTCTGGGGAATTCCTGGACACAAAGGAC
  AGACAGGCAGAAGAGGACAGACAGATGGACACTGAGGCTGCTGCATCTGAAGCCCCCCAG
  GATGTGACCTACGCCCGGCTGCACAGCTTTACCCTCAGACAGAAGGCAACTGAGCCTCCT
  CCATCCCAGGAAGGGGCCTCTCCAGCTGAGCCCAGTGTCTATGCCACTCTGGCCATCCAC
  TAATCCAGGGGGGACCCAGACCCCACAAGCCATGGAGACTCAGGACCCCAGAAGGCATGG
  AAGCTGCCTCCAGTAGACATCACTGAACCCCAGCCAGCCCAGACCCCTGACACAGACCAC
  TAGAAGATTCCGGGAACGTTGGGAGTCACCTGATTCTGCAAAGATAAATAATATCCCTGC
  ATTATCAAAATAAAGTAGCAGACCTCTCAAAAAAAAAAAAAAAAAACTCGAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006864 unedited
  ACCGCGGCCCGCAATCTAGNATCGAGTTTTTTTTTTTTTTTTTTGAGAGGTCTGCTACTT
  TATTTTGATAATGCAGGGATATTATTTATCTTTGCAGAATCAGGTGACTCCCAACGTTCC
  CGGAATCTTCTAGTGGTCTGTGTCAGGGGTCTGGGCTGGCTGGGGTTCAGTGATGTCTAC
  TGGAGGCAGCTTCCATGCCTTCTGGGGTCCTGAGTCTCCATGGCTTGTGGGGTCTGGGTC
  CCCCCTGGATTAGTGGATGGCCAGAGTGGCATAGACACTGGGCTCAGCTGGAGAGGCCCC
  TTCCTGGGATGGAGGAGGCTCAGTTGCCTTCTGTCTGAGGGTAAAGCTGTGCAGCCGGGC
  GTAGGTCACATCCTGGGGGGCTTCAGATGCAGCAGCCTCAGTGTCCATCTGTCTGTCCTC
  TTCTGCCTGTCTGTCCTTTGTGTCCAGGAATTCCCCAGACAGTGGGGAGGGAGGAGAGGC
  CATTTCTCTCCTAGGTCTGGAGTGTTTCACCTTGGCATACGTCACTGCCTGNGGGTCTTC
  ATCGTGTGGGCTCCGAGTGTCCATTTCCACCCCGTCCTCAGGCTGTGTGTTCTTCACGGC
  AGCACAGAAGTTTTCTCCCTGGACGTCAGCAGCTGGGCTGGACCTCCTCTGTAGGCCCCC
  GTCCTTGGGCTCTGGGCTCGCAGCCCCTGGNAGACGTTGGAATTCAGCCTGTCTCTGGGC
  CAATGTCCTGTGTTTTCCCTGACGCCAGNTGTGGANGAGGGAGAATAGNNAGANNGGANA
  NAANCCCGATGGGGCACCCCCAAGACCCCGATCAGTACCTTCCAGTGCCTTCTAGGACAC
  TGTTGTGGGACTGACCCTTGTAGCATGAGGGGGTTGGCCCTCACGGCCTCCCCCTGTTGA
  AACGGACCTCTGGGTTGAGGCCCGCCACCCTCTCAGGACTCTGGATATTAGCCCCACGGG
  TCCCCCGGGTGGTCTCCTCTACCCCCCACACCCTTCCCACATCTCCGCTCTCCCCTCCCC
  TTGGCACACAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006864
• ORF Size: 1896 bp
• Insert Size: 1610
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006864.1, NP_006855.1
• RefSeq Size: 2170
• RefSeq ORF: 1896
• Locus ID: 11025
• Domains: ig, IGc2, IG
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: B cell receptor signaling pathway
• Gene Summary: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The resulting protein (isoform 2) is 1 aa shorter than isoform 1.