PHLPP (PHLPP1) (NM_194449) Human Untagged Clone

CAT#: SC108817

PHLPP1 (untagged)-Human PH domain and leucine rich repeat protein phosphatase 1 (PHLPP1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PHLPP1
• Synonyms: PHLPP; PLEKHE1; PPM3A; SCOP
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_194449, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGCCCGCCGCCGCGGCCACGGTACAGCGACTCCCCGAGCTCGGCAGGGAGGACCGAGCTTCGGCTC
  CGGCGGCCGCCGCTGCGGCAGCAGCAGCAGCAGCGGCGGCCGCGGCGGCTCTGGCGGCGGCGGCCGGGGG
  CGGCCGGAGTCCGGAGCCCGCGCTGACCCCGGCGGCCCCGAGCGGCGGGAACGGCAGCGGCAGCGGGGCG
  CGGGAAGAGGCCCCAGGCGAGGCGCCGCCGGGGCCGCTGCCGGGCAGAGCGGGGGGTGCCGGGCGCAGGA
  GGCGGCGCGGGGCGCCCCAGCCCATTGCCGGCGGGGCTGCCCCCGTACCCGGGGCCGGCGGCGGCGCCAA
  CTCCCTCCTGCTGAGGAGAGGGCGGCTGAAGAGGAATCTGTCCGCGGCCGCCGCGGCCGCCTCCTCGTCG
  TCGTCGTCCTCGGCCGCTGCTGCCTCGCACTCCCCCGGCGCTGCCGGCCTCCCCGCCTCCTGCTCGGCCT
  CGGCGTCGCTGTGCACCCGGAGCCTGGACAGGAAGACGCTGCTTCTGAAGCACCGGCAGACGCTGCAGCT
  GCAGCCGTCGGACCGGGACTGGGTGAGGCACCAGCTCCAGCGCGGCTGCGTGCACGTCTTCGACCGCCAC
  ATGGCCTCGACCTACCTGCGCCCGGTGCTCTGCACACTGGACACCACGGCCGGCGAGGTGGCCGCCCGCC
  TGCTGCAGCTGGGCCACAAAGGCGGCGGCGTGGTGAAGGTGCTGGGCCAGGGGCCCGGAGCCGCCGCCGC
  CCGGGAGCCCGCTGAACCGCCCCCCGAGGCCGGCCCCCGGCTGGCGCCCCCGGAGCCGCGGGACTCGGAG
  GTACCGCCCGCGAGGAGCGCGCCGGGTGCCTTCGGGGGGCCTCCGCGCGCGCCCCCCGCCGACCTACCCC
  TGCCCGTCGGCGGCCCGGGCGGGTGGTCGCGCCGCGCCAGCCCAGCGCCCTCGGACTCCAGCCCCGGCGA
  GCCGTTCGTTGGGGGCCCTGTCTCTTCGCCCCGCGCCCCACGGCCTGTGGTCTCCGACACCGAGAGCTTC
  AGTCTGAGTCCCAGCGCCGAGAGCGTGTCTGACCGGTTGGACCCCTACAGCAGCGGCGGCGGCTCCTCGT
  CGTCGTCGGAAGAGCTCGAGGCCGACGCAGCCTCGGCCCCGACGGGGGTCCCGGGCCAGCCCCGCCGTCC
  CGGCCACCCCGCGCAGCCCCTCCCGCTTCCCCAGACGGCTTCCTCGCCTCAGCCGCAGCAGAAAGCCCCG
  AGGGCCATTGACAGCCCGGGCGGGGCCGTCCGCGAGGGGTCGTGCGAGGAGAAGGCAGCGGCAGCCGTGG
  CCCCGGGAGGCCTCCAGTCTACCCCCGGGAGGAGCGGGGTGACCGCGGAGAAGGCGCCTCCGCCGCCCCC
  GCCGCCCACCCTGTACGTGCAGCTCCACGGAGAGACCACCCGGCGCTTGGAGGCGGAGGAGAAGCCATTG
  CAGATCCAAAATGACTACCTCTTCCAACTGGGATTTGGGGAGCTGTGGAGGGTGCAGGAGGAAGGCATGG
  ACTCGGAGATTGGCTGCCTCATCCGCTTCTATGCAGGAAAACCTCACAGCACGGGTAGCTCTGAACGGAT
  TCAGCTCTCAGGAATGTATAATGTCCGTAAAGGCAAGATGCAGTTGCCAGTGAACCGATGGACAAGACGC
  CAAGTCATCCTATGTGGGACCTGCCTGATAGTATCATCTGTGAAAGACAGCTTGACCGGAAAGATGCATG
  TTCTGCCACTAATTGGTGGAAAAGTAGAAGAAGTGAAAAAGCACCAACACTGTTTAGCATTTAGCTCCTC
  TGGACCCCAAAGCCAGACTTACTACATTTGCTTTGATACTTTCACAGAATACTTAAGGTGGCTGCGACAA
  GTCTCCAAGGTTGCATCCCAGCGCATTAGCTCAGTGGACCTCTCGTGTTGTAGCCTGGAACATCTGCCTG
  CCAACCTCTTCTACAGCCAAGACCTCACTCATCTCAATTTAAAACAAAACTTCCTAAGGCAGAACCCTAG
  CCTTCCAGCTGCCAGGGGGCTTAATGAACTGCAAAGGTTCACCAAGTTGAAGAGTCTTAACCTTTCCAAT
  AATCATTTAGGGGACTTCCCACTGGCAGTCTGCAGTATTCCAACCCTGGCAGAGCTGAACGTGTCCTGCA
  ATGCCCTGCGATCAGTCCCGGCAGCCGTTGGAGTGATGCACAACTTACAGACATTTTTGTTGGATGGAAA
  CTTTCTCCAATCCCTTCCTGCTGAGTTGGAGAACATGAAGCAGCTTAGTTATCTGGGTCTTTCTTTCAAT
  GAATTTACTGACATTCCCGAAGTATTGGAGAAATTGACTGCTGTGGATAAACTTTGTATGTCTGGAAACT
  GTGTGGAGACCCTTAGGCTACAGGCTTTAAGAAAAATGCCTCACATTAAACATGTGGATCTAAGGTTGAA
  CGTAATTAGGAAGCTGATAGCAGATGAAGTGGACTTTCTACAGCATGTTACTCAGCTTGACCTACGAGAC
  AATAAGCTTGGTGATCTAGATGCTATGATTTTCAACAACATTGAAGTTTTACACTGTGAAAGGAATCAAC
  TGGTCACATTAGACATCTGTGGCTATTTCCTAAAAGCGCTCTATGCCTCTTCTAATGAACTTGTTCAACT
  TGATGTTTACCCAGTTCCAAATTATCTGTCCTACATGGATGTTTCAAGGAACCGCTTAGAAAATGTGCCT
  GAGTGGGTATGTGAAAGCCGAAAGCTAGAAGTTTTGGATATTGGCCATAATCAAATATGTGAACTTCCTG
  CCCGCTTATTTTGTAATAGCAGTCTCCGGAAACTACTGGCAGGACACAACCAGTTGGCAAGGCTGCCTGA
  AAGGCTAGAAAGAACCTCGGTGGAGGTCTTGGATGTGCAACACAACCAGCTCCTTGAGCTCCCACCTAAC
  CTTCTGATGAAGGCTGACAGCCTGAGATTCCTGAACGCCTCTGCGAACAAACTGGAAAGCCTTCCTCCAG
  CCACGCTTTCCGAAGAGACAAACAGTATCTTACAAGAGTTGTATTTGACAAATAACAGCCTCACAGACAA
  ATGTGTGCCCTTGTTAACGGGACACCCCCATTTGAAGATCCTTCACATGGCCTATAACCGACTTCAGAGT
  TTTCCAGCAAGTAAAATGGCGAAACTGGAGGAACTTGAAGAAATTGATCTCAGTGGGAATAAGCTGAAAG
  CCATCCCAACAACGATCATGAATTGCAGGCGCATGCACACCGTGATTGCTCACTCCAACTGCATCGAGGT
  CTTTCCCGAAGTTATGCAGCTCCCAGAGATCAAGTGTGTGGACCTGAGCTGTAATGAGCTAAGTGAAGTC
  ACATTACCAGAAAACCTGCCTCCCAAACTGCAGGAGCTAGACCTGACTGGAAACCCGCGCCTTGTCCTTG
  ATCACAAAACCCTGGAACTACTGAATAATATCCGCTGTTTCAAGATTGATCAGCCTTCTACAGGAGACGC
  TTCCGGAGCCCCAGCTGTATGGAGTCATGGTTACACTGAAGCTTCGGGGGTAAAAAACAAGTTGTGTGTC
  GCAGCCCTGTCGGTGAATAACTTCTGTGACAACCGCGAAGCCCTGTATGGTGTGTTTGACGGAGACCGGA
  ATGTGGAGGTGCCCTACCTTCTCCAGTGCACTATGAGTGACATTTTGGCTGAAGAGCTGCAAAAAACAAA
  AAACGAAGAAGAATACATGGTCAATACATTCATTGTCATGCAAAGGAAACTTGGAACTGCTGGGCAGAAG
  CTTGGTGGTGCCGCTGTCCTTTGTCATATCAAGCATGACCCTGTGGATCCAGGAGGATCCTTCACCTTGA
  CCTCTGCTAATGTGGGCAAGTGCCAAACAGTTCTCTGTCGAAATGGAAAGCCGCTGCCTCTGTCCAGATC
  TTACATCATGAGCTGTGAAGAAGAGCTGAAGAGGATTAAACAGCACAAGGCCATTATCACTGAGGATGGC
  AAGGTGAACGGAGTGACTGAGTCCACGCGCATCCTGGGCTACACCTTCCTCCATCCCAGTGTGGTGCCTC
  GCCCCCACGTGCAGTCCGTGCTCCTGACTCCCCAGGATGAGTTCTTCATCCTAGGCAGTAAGGGGTTGTG
  GGACAGCCTGTCCGTCGAGGAGGCCGTGGAAGCCGTGCGCAACGTGCCCGATGCCCTGGCTGCTGCCAAG
  AAGCTGTGTACCCTGGCCCAGAGCTACGGCTGCCACGACAGCATCAGCGCTGTGGTGGTGCAGCTCAGTG
  TCACTGAGGACAGCTTCTGCTGCTGCGAGCTCAGCGCCGGTGGGGCTGTGCCACCACCCAGTCCTGGCAT
  CTTTCCTCCCTCAGTGAACATGGTGATCAAGGATCGGCCCTCAGATGGGCTGGGCGTGCCGTCCTCCAGC
  AGCGGCATGGCTTCCGAGATTAGCAGTGAGCTCTCCACTTCTGAGATGAGCAGCGAGGTGGGGTCAACAG
  CCTCCGATGAGCCCCCGCCCGGAGCCCTAAGCGAGAACAGCCCTGCCTACCCCAGTGAGCAGCGCTGCAT
  GCTCCACCCCATCTGTCTGTCCAACTCCTTCCAGCGCCAGCTATCCAGCGCCACGTTCTCTAGCGCCTTC
  TCCGACAACGGCCTTGACAGTGACGATGAGGAGCCCATCGAGGGCGTCTTCACCAACGGCAGCCGGGTGG
  AGGTGGAGGTGGACATCCACTGCAGCCGGGCCAAGGAGAAGGAGAAACAGCAGCACCTGCTTCAGGTGCC
  AGCAGAGGCCAGTGATGAGGGCATTGTCATCAGCGCCAACGAGGATGAGCCAGGTCTGCCCAGGAAGGCA
  GACTTCTCTGCCGTTGGGACCATTGGGCGCCGGAGGGCCAATGGCTCTGTTGCGCCCCAGGAAAGGAGCC
  ACAATGTGATAGAGGTGGCTACAGACGCACCTCTTCGAAAGCCTGGAGGCTATTTTGCTGCCCCGGCTCA
  GCCGGATCCTGATGATCAGTTTATCATACCCCCGGAGCTGGAAGAGGAGGTCAAAGAAATCATGAAGCAT
  CACCAGGAGCAACAGCAGCAGCAGCAGCCGCCACCACCCCCTCAGCTCCAGCCGCAGCTGCCGCGGCACT
  ACCAGCTGGACCAGCTGCCAGATTATTACGACACGCCACTATGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_194449 unedited
  CCGCGTATTCGGCACGAGGGAGGAGCGGGGTGACCGCGGAGAAGCGCCTCCGCCGCCCCC
  GCCGCCCACCCTGTACGTGCAGCTCCACGGAGAGACCACCCGGCGCTTGGAGGCGGAGGA
  GAAGCCATTGCAGATCCAAAATGACTACCTCTTCCAACTGGGATTTGGGGAGCTGTGGAG
  GGTGCAGGAGGAAGGCATGGACTCGGAGATTGGCTGCCTCATCCGCTTCTATGCAGGAAA
  ACCTCACAGCACGGGTAGCTCTGAACGGATTCAGCTCTCAGGAATGTATAATGTCCGTAA
  AGGCAAGATGCAGTTGCCAGTGAACCGATGGACAAGACGCCAAGTCATCCTATGTGGGAC
  CTGCCTGATAGTATCATCTGTGAAAGACAGCTTGACCGGAAAGATGCATGTTCTGCCACT
  AATTGGTGGAAAAGTAGAAGAAGTGAAAAAGCACCAACACTGTTTAGCATTTAGCTCCTC
  TGGACCCCAAAGCCAGACTTACTACATTTGCTTTGATACTTTCACAGAATACTTAAGGTG
  GCTGCGACAAGTCTCCAAGGTTGCATCCCAGCGCATTAGCTCAGTGGACCTCTCGTGTTG
  TAGCCTGGAACATCTGCCTGCCAACCTCTTCTACAGCCAAGACCTCACTCATCTCAATTT
  AAAACAAAACTTCCTAAGGCAGAACCCTAGCCTTCCAGCTGCCAGGGGGCTTAATGAACT
  GCAAGGGTTCACCAAGTGAAGAAGTCTACCCCTTTCCATATCATTTAGGGGACTTCCTCT
  GGCAGNCTGCAGTATTCCAACCTGGCAAGCTGAAACGGGTCCTGCAATGCCCTGGGATCA
  GTCCCCGCAGCGGTTGGAAGTGATGCACACCTACAAACT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_194449 unedited
  NCACCTTGTTTGTTTCTGTTTATTGTAACAAAATTATGACATGTCCATTTGTGCATTCTG
  CTTGAGTATAACTCTGGGTATGTAAATGGCCTAATGGGGCACTATACAACCATGCTGATT
  GTGGCAGCAGTAAGGAACACAGTTAAAAGTGTCTGTCAAAGTGGGAAGGCTGGGACAGGG
  GAGGAAAATGGGTTCAGGGCCCTTGGGTGCAGGTTCTTGTCCAGTGGCCTAAGATCCATT
  TCCTCCGGACAGAAACACTGCAGCTGCTCAGCCTCCTCATTCAGTGAAGTGAGGGTGAGT
  TGTGAGGCAGGCAGGCTCCTCAAAGGGGAGGGGGAGGGGAAACGTCAGTTACTTGGGCTG
  TGTCCTTACGCCAAGACTACAAAACATCGTAAGCCTCACTATACAACACTGAGCTATTTA
  CAATGGAAATTCTCAATCAGCTGTTCTCTCAGAGAAAATTAATGAATCCCAGTGACTTAA
  GTCACCTGACAAAGTAAAGCAACTCCTAGGAGTTAGTCTCCCCATTCTACGAATGTCTAT
  TATTTTCAGGACATCGACCATACAAAACCTAATAAAACTAGCCCCAGGCCTTTTGCTCGC
  GAACACACGCCGAATTACGCTACTAGTAAATACTTTAACATCTGCCGACTGGCATGCCTT
  GTCAACCAACAGAATAGAGCCTGTTTCAAACATTTTACCCTATTCATTATATAGGAGCCC
  TGACCACAACCATACGAATTGGTTCTTTTTTCTCCCCGACCCAGAGTTTTTCCGCGCACC
  AATTACATAAGGTCTTATCATCGTCTTAACGAACCACCGGCGCAAAACAGCCGGTTTTTA
  TAAACAAAACCACTCACTAAAGAACCTGTTGGTATTTTCACACCAACACACCGCCGCCCA
  ATATCGCACCACATCCAATGGGTCACAACACAACCCTCCTTATTGT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_194449
• ORF Size: 3618 bp
• Insert Size: 4500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_194449.1, NP_919431.1
• RefSeq Size: 4798
• RefSeq ORF: 3618
• Locus ID: 23239
• Gene Summary: This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. [provided by RefSeq, Dec 2011]