LY108 (SLAMF6) (NM_052931) Human Untagged Clone

CAT#: SC108856

SLAMF6 (untagged)-Human SLAM family member 6 (SLAMF6), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SLAMF6
• Synonyms: CD352; KALI; KALIb; Ly108; NTB-A; NTBA; SF2000
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC108856 sequence for NM_052931 edited (data generated by NextGen Sequencing)
  ATGTTGTGGCTGTTCCAATCGCTCCTGTTTGTCTTCTGCTTTGGCCCAGGGAATGTAGTT
  TCACAAAGCAGCTTAACCCCATTGATGGTGAACGGGATTCTGGGGGAGTCAGTAACTCTT
  CCCCTGGAGTTTCCTGCAGGAGAGAAGGTCAACTTCATCACTTGGCTTTTCAATGAAACA
  TCTCTTGCCTTCATAGTACCCCATGAAACCAAAAGTCCAGAAATCCACGTGACTAATCCG
  AAACAGGGAAAGCGACTGAACTTCACCCAGTCCTACTCCCTGCAACTCAGCAACCTGAAG
  ATGGAAGACACAGGCTCTTACAGAGCCCAGATATCCACAAAGACCTCTGCAAAGCTGTCC
  AGTTACACTCTGAGGATATTAAGACAACTGAGGAACATACAAGTTACCAATCACAGTCAG
  CTATTTCAGAATATGACCTGTGAGCTCCATCTGACTTGCTCTGTGGAGGATGCAGATGAC
  AATGTCTCATTCAGATGGGAGGCCTTGGGAAACACACTTTCAAGTCAGCCAAACCTCACT
  GTCTCCTGGGACCCCAGGATTTCCAGTGAACAGGACTACACCTGCATAGCAGAGAATGCT
  GTCAGTAATTTATCCTTCTCTGTCTCTGCCCAGAAGCTTTGCGAAGATGTTAAAATTCAA
  TATACAGATACCAAAATGATTCTGTTTATGGTTTCTGGGATATGCATAGTCTTCGGTTTC
  ATCATACTGCTGTTACTTGTTTTGAGGAAAAGAAGAGATTCCCTATCTTTGTCTACTCAG
  CGAACACAGGGCCCCGAGTCCGCAAGGAACCTAGAGTATGTTTCAGTGTCTCCAACGAAC
  AACACTGTGTATGCTTCAGTCACTCATTCAAACAGGGAAACAGAAATCTGGACACCTAGA
  GAAAATGATACTATCACAATTTACTCCACAATTAATCATTCCAAAGAGAGTAAACCCACT
  TTTTCCAGGGCAACTGCCCTTGACAATGTCGTGTAA
  
  Clone variation with respect to NM_052931.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_052931 unedited
  ATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGATTGACTGCCTC
  AAGGTCTCAAGCACCAGTCTTCACCGCGGAAAGCTGTTGTGGCTGTTCCAATCGCTCCTG
  TTTGTCTTCTGCTTTGGCCCAGGGAATGTAGTTTCACAAAGCAGCTTAACCCCATTGATG
  GTGAACGGGATTCTGGGGGAGTCAGTAACTCTTCCCCTGGAGTTTCCTGCAGGAGAGAAG
  GTCAACTTCATCACTTGGCTTTTCAATGAAACATCTCTTGCCTTCATAGTACCCCATGAA
  ACCAAAAGTCCAGAAATCCACGTGACTAATCCGAAACAGGGAAAGCGACTGAACTTCACC
  CAGTCCTACTCCCTGCAACTCAGCAACCTGAAGATGGAAGACACAGGCTCTTACAGAGCC
  CAGATATCCACAAAGACCTCTGCAAAGCTGTCCAGTTACACTCTGAGGATATTAAGACAA
  CTGAGGAACATACAAGTTACCAATCACAGTCAGCTATTTCAGAATATGACCTGTGAGCTC
  CATCTGACTTGCTCTGTGGAGGATGCAGATGACAATGTCTCATTCAGATGGGAGGCCTTG
  GGAAACACACTTTCAAGTCAGCCAAACCTCACTGTCTCCTGNNGACCCCAGATTTCCAGT
  GAACAGGACTACACCTGCATAGCAGAGAATGCTGNCAGTAATTTATCCTTCTCTGTCTCT
  GCCCAAAAGCTTTGCGAAAATGTTNAAATTCATATACAGATACCANNATGATNCTGTTTA
  TGGTTTCTGGGATATGCATAGTCTTCGGTTTCATCATACTGCTGTTACCTTGTNNTGAGA
  AAGAAGAGATTCCTATCTTTGTCTACTCAGCGACACAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_052931 unedited
  ATGAGCCTGGGGNAGGGGTCACAGGGNATGCCACCCGGGATCTGTTCAGGAAACAGCTAT
  GACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTATTTTATTTATTTATT
  TTTTGAGACAGAGTCTCACTCTGTCACCCAGACTGGAATACATTGGCATGATTTTGGCTC
  ACTGGAACCTCCACCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGTCTCTCAAGTAGCTG
  GGATTTTAGGGGTGCACCACCACGCCTGGCTAATTTTTTTGTATTTTTAGTAAAGACGGG
  GTTTCACCAAGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAAGTGATCTCCCCCCTTG
  GCCTCCCAAAGTACTGGGATTACAGGTGTGAGCCACCATGCCCAGCCTAGAAGATTCATT
  TTANAAAGAGTGGTCCGGGAAGGTTTCTCTTAAGAGGTGACATATTTAAAATTAACCCTA
  ACCAATAGGAGGACCCCATCCCGCCCCAGAAGGGCCTGCCGGAAGATGTAAATTATTTAC
  CTCACCAACTTTTTCTTTTAATACAAGCACCCTGAAGAATATCATGGAGGCCTCCTTACA
  AAAGTGTCTTAAACGCTCATGGTATCCTTAGGCCTGTAAGTGTGCCCCCACCACCCCCCG
  TCCCTGTAAACCGGGTTTCCTTTTTTCACTGGATTGTGTAATCCCCCCCGGGCCTTTTAC
  CCCGGTAATCTTGTAGGCACCCCTTTTTTCTCACATTACTATACTCCCGGCATTTCTTAA
  GACTAATCTCCTCGTACGAACCCCCCCCACTTACATCGAAGTCAGANCGCTCGTGTTTTT
  ACGGGTGTGATTGTTTGTGT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_052931
• ORF Size: 996 bp
• Insert Size: 3000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_052931.3, NP_443163.1
• RefSeq Size: 2776
• RefSeq ORF: 996
• Locus ID: 114836
• Domains: ig, IG
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2010]
  Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, compared to variant 1, which results in an isoform (2) that is one amino acid shorter than isoform 1.