ANKRD15 (KANK1) (NM_153186) Human Untagged Clone

CAT#: SC108880

KANK1 (untagged)-Human KN motif and ankyrin repeat domains 1 (KANK1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KANK1
• Synonyms: ANKRD15; CPSQ2; KANK
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_153186 edited
  ATGGAGACCCGGAGAAGACTGGAACAGGAGAGAGCCACCATGCAGATGACACCGGGTGAG
  TTCAGAAGGCCCAGGCTGGCCAGTTTTGGAGGCATGGGCACCACAAGCTCCCTCCCTTCT
  TTTGTGGGTTCTGGAAACCACAATCCTGCCAAGCACCAGCTTCAGAATGGATACCAAGGT
  AATGGGGATTATGGTAGCTATGCCCCAGCTGCTCCCACCACTTCCTCCATGGGGAGCTCC
  ATCCGCCACAGCCCCCTGAGCTCAGGGATCTCCACCCCAGTGACCAACGTGAGCCCCATG
  CACCTGCAGCACATCCGCGAGCAGATGGCCATTGCTCTGAAACGCCTGAAGGAGCTGGAG
  GAGCAGGTGCGAACCATCCCTGTGCTCCAGGTAAAGATCTCTGTCTTGCAAGAAGAGAAA
  AGGCAGTTGGTCTCACAGCTGAAAAACCAAAGGGCTGCATCCCAGATCAATGTCTGTGGT
  GTGAGGAAGCGGTCCTATAGTGCGGGGAACGCCTCCCAGCTGGAACAGCTCTCCCGGGCC
  CGAAGAAGTGGCGGGGAATTATACATTGACTATGAGGAGGAAGAAATGGAGACCGTAGAA
  CAGAGCACGCAGAGGATAAAGGAGTTCCGGCAACTTACAGCAGACATGCAAGCCCTGGAG
  CAGAAGATCCAGGACAGCAGCTGTGAGGCCTCCTCAGAGCTCAGGGAGAATGGAGAGTGC
  CGGTCTGTGGCTGTGGGTGCCGAGGAGAACATGAACGACATCGTCGTGTACCACAGAGGC
  TCCAGGTCCTGTAAGGATGCAGCTGTAGGGACACTTGTTGAGATGAGAAATTGTGGGGTC
  AGCGTGACAGAGGCCATGCTTGGAGTGATGACTGAAGCTGACAAAGAAATTGAGCTGCAA
  CAGCAGACCATAGAATCCTTGAAGGAAAAGATCTATCGCCTAGAAGTACAGCTTAGAGAA
  ACCACCCATGACCGGGAGATGACTAAACTGAAACAAGAGCTGCAGGCTGCTGGATCGAGG
  AAAAAGGTTGACAAAGCCACGATGGCCCAGCCGCTTGTTTTCAGTAAGGTGGTGGAGGCA
  GTGGTGCAGACCAGAGACCAAATGGTCGGCAGTCACATGGACCTGGTGGACACGTGTGTT
  GGGACCTCCGTGGAAACAAACAGTGTAGGCATCTCCTGCCAGCCTGAATGTAAGAATAAA
  GTCGTAGGGCCTGAGCTGCCTATGAATTGGTGGATTGTTAAGGAGAGGGTGGAAATGCAT
  GACCGATGTGCTGGGAGGTCTGTGGAAATGTGTGACAAGAGTGTGAGTGTGGAAGTCAGC
  GTCTGCGAAACAGGCAGCAACACAGAGGAGTCTGTGAACGACCTCACACTCCTCAAGACA
  AACTTGAATCTCAAAGAAGTGCGGTCTATCGGTTGTGGAGATTGTTCTGTTGACGTGACC
  GTCTGCTCTCCAAAGGAGTGCGCCTCCCGGGGCGTGAACACTGAGGCTGTTAGCCAGGTG
  GAAGCTGCCGTCATGGCAGTGCCTCGTACTGCAGACCAGGACACTAGCACAGATTTGGAA
  CAGGTGCACCAGTTCACCAACACCGAGACGGCCACCCTCATAGAGTCCTGCACCAACACT
  TGTCTAAGCACTTTGGACAAGCAGACCAGCACCCAGACTGTGGAGACGCGGACAGTAGCT
  GTAGGAGAAGGCCGTGTCAAGGACATCAACTCCTCCACCAAGACGCGGTCCATTGGTGTT
  GGAACGTTGCTTTCTGGCCATTCTGGGTTTGACAGGCCATCAGCTGTGAAGACCAAAGAG
  TCAGGTGTGGGGCAGATAAATATTAACGACAACTATCTGGTTGGTCTCAAAATGAGGACT
  ATAGCTTGTGGGCCACCACAGTTGACTGTGGGGCTGACAGCCAGCAGAAGGAGCGTGGGG
  GTTGGGGATGACCCTGTAGGGGAATCTCTGGAGAACCCCCAGCCTCAAGCTCCACTTGGA
  ATGATGACTGGCCTGGATCACTACATTGAGCGTATCCAGAAGCTGCTGGCAGAACAGCAG
  ACACTGCTGGCTGAGAACTACAGTGAACTGGCAGAAGCTTTCGGGGAACCTCACTCACAG
  ATGGGCTCCCTCAACTCTCAGCTCATCAGCACCCTGTCGTCTATCAACTCTGTCATGAAA
  TCTGCAAGCACTGAAGAGCTGAGGAACCCTGACTTCCAGAAAACCAGTCTGGGTAAAATC
  ACAGGCAATTATTTGGGATATACCTGTAAGTGTGGGGGCCTTCAGTCAGGAAGTCCCTTA
  AGCTCCCAGACATCCCAGCCTGAGCAAGAAGTGGGGACCTCAGAAGGAAAGCCAATCAGC
  AGCCTGGATGCCTTCCCCACTCAGGAAGGTACGCTGTCTCCAGTGAACCTGACAGACGAC
  CAGATCGCCGCTGGCCTCTATGCATGTACAAACAATGAAAGTACACTGAAGTCCATCATG
  AAGAAGAAAGATGGTAACAAAGATTCAAATGGCGCAAAAAAGAATCTTCAGTTTGTTGGC
  ATTAATGGAGGGTATGAAACAACTTCAAGTGATGATTCCAGCTCAGATGAAAGCTCTTCT
  TCCGAGTCAGATGACGAGTGTGATGTCATTGAGTATCCTCTTGAAGAAGAGGAGGAGGAG
  GAGGATGAAGACACTCGGGGAATGGCAGAAGGGCACCATGCAGTTAATATTGAAGGTTTG
  AAGTCTGCCAGGGTGGAAGATGAAATGCAGGTTCAAGAATGTGAACCTGAGAAGGTGGAA
  ATCAGAGAGAGGTATGAATTAAGTGAAAAGATGTTGTCTGCATGCAACTTACTGAAAAAT
  ACTATAAATGACCCCAAAGCTTTGACCAGCAAAGATATGAGGTTCTGTCTGAACACCGTC
  CAGCACGAGTGGTTCCGCGTGTCCAGTCAGAAGTCAGCCATTCCAGCCATGGTGGGGGAC
  TACATAGCTGCTTTTGAGGCCATTTCCCCAGATGTCCTCCGCTATGTCATCAACTTGGCA
  GACGGCAACGGCAACACAGCCCTCCATTACAGCGTGTCCCACTCCAACTTCGAGATTGTG
  AAGCTGCTGTTAGATGCCGATGTGTGTAATGTGGATCACCAGAACAAGGCAGGCTACACC
  CCCATCATGTTGGCGGCCCTCGCCGCTGTGGAAGCAGAGAAGGACATGCGGATTGTGGAA
  GAACTCTTCGGCTGTGGGGATGTGAATGCCAAAGCTAGTCAGGCGGGACAGACGGCCCTC
  ATGCTGGCGGTCAGTCACGGACGGATAGACATGGTGAAGGGCCTTCTGGCCTGTGGGGCT
  GATGTCAACATCCAGGATGACGAGGGCTCCACGGCCCTCATGTGTGCCAGCGAGCACGGG
  CACGTGGAGATTGTCAAGCTGCTGCTGGCCCAGCCCGGCTGCAACGGTCACCTAGAGGAC
  AACGATGGCAGCACTGCGCTCTCAATCGCCCTGGAAGCAGGACACAAGGACATCGCTGTT
  CTTCTGTATGCCCATGTCAACTTTGCAAAAGCCCAGTCTCCGGGCACCCCTAGGCTTGGA
  AGGAAGACGTCTCCTGGCCCCACCCACCGAGGTTCATTTGATTGA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_153186
• ORF Size: 3585 bp
• Insert Size: 5100
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: no

Reference Data

• RefSeq: NM_153186.3, NP_694856.1
• RefSeq Size: 5263
• RefSeq ORF: 3585
• Locus ID: 23189
• Domains: ANK
• Gene Summary: The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5;9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2014]
  Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream in-frame start codon, compared to variant 1. The resulting isoform (b, also known as Kank-S) is shorter at the N-terminus, compared to isoform a.