GERP (TRIM8) (NM_030912) Human Untagged Clone

CAT#: SC109091

TRIM8 (untagged)-Human tripartite motif containing 8 (TRIM8)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TRIM8
• Synonyms: GERP; RNF27
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC109091 sequence for NM_030912 edited (data generated by NextGen Sequencing)
  ATGGCGGAGAATTGGAAGAACTGCTTCGAGGAGGAGCTCATCTGCCCTATCTGCCTGCAC
  GTTTTCGTGGAGCCAGTGCAGCTGCCGTGCAAACACAACTTCTGCCGGGGCTGCATCGGC
  GAGGCGTGGGCCAAGGACAGCGGCCTCGTACGCTGCCCAGAGTGCAACCAGGCCTACAAC
  CAGAAGCCGGGCCTGGAGAAGAACCTGAAGCTCACCAACATCGTGGAGAAGTTCAATGCC
  CTGCACGTGGAGAAGCCGCCGGCGGCGCTGCACTGCGTGTTCTGCCGCCGCGGCCCCCCG
  CTGCCCGCGCAGAAGGTCTGCCTGCGCTGCGAGGCGCCCTGCTGCCAGTCCCACGTGCAG
  ACGCACCTGCAGCAGCCCTCCACCGCCCGCGGGCACCTCCTGGTGGAGGCGGACGACGTG
  CGGGCCTGGAGCTGCCCGCAGCACAACGCCTACCGCCTCTACCACTGCGAGGCCGAGCAG
  GTGGCCGTGTGCCAGTACTGCTGCTACTACAGCGGCGCGCATCAGGGACACTCGGTGTGC
  GACGTGGAGATCCGAAGGAATGAAATCCGGAAGATGCTCATGAAGCAGCAGGACCGGCTG
  GAGGAGCGAGAGCAGGACATTGAGGACCAGCTGTACAAACTCGAGTCAGACAAGCGCCTG
  GTGGAGGAGAAAGTGAACCAACTGAAGGAGGAAGTTCGGCTGCAGTACGAGAAGCTGCAC
  CAGCTGCTGGACGAGGACCTGCGGCAGACAGTGGAGGTCCTAGACAAGGCCCAGGCCAAG
  TTCTGCAGCGAGAACGCAGCGCAGGCGCTGCACCTCGGGGAGCGCATGCAGGAGGCCAAG
  AAGCTGCTGGGCTCCCTGCAGCTGCTCTTTGATAAGACGGAGGATGTCAGCTTCATGAAG
  AACACCAAGTCTGTGAAAATCCTGATGGACAGGACCCAGACCTGCACGAGCAGCAGCCTT
  TCCCCCACTAAGATCGGCCACCTGAACTCCAAGCTCTTCCTGAACGAAGTGGCCAAGAAG
  GAGAAGCAGCTGCGGAAAATGCTAGAAGGCCCCTTCAGCACGCCGGTGCCCTTCCTGCAG
  AGTGTCCCCCTGTACCCTTGCGGCGTGAGCAGCTCTGGGGCGGAAAAGCGCAAGCACTCA
  ACGGCCTTCCCAGAGGCCAGTTTCCTAGAGACGTCGTCGGGCCCTGTGGGCGGCCAGTAC
  GGGGCGGCGGGCACAGCCAGCGGTGAGGGCCAGTCTGGGCAGCCCCTGGGGCCCTGCAGC
  TCCACGCAGCACTTGGTGGCCCTGCCGGGCGGCGCCCAACCAGTGCACTCAAGCCCCGTG
  TTCCCCCCATCGCAGTATCCCAATGGCTCCGCCGCCCAGCAGCCCATGCTCCCCCAGTAT
  GGCGGCCGCAAGATTCTCGTCTGTTCTGTGGACAACTGTTACTGTTCTTCCGTGGCCAAC
  CATGGCGGCCACCAGCCCTACCCCCGCTCCGGCCACTTTCCCTGGACAGTGCCCTCGCAG
  GAGTACTCACACCCGCTCCCGCCCACACCCTCCGTCCCCCAGTCCCTTCCCAGCCTGGCG
  GTCAGAGACTGGCTTGACGCCTCCCAGCAGCCCGGCCACCAGGATTTCTACAGGGTGTAT
  GGGCAGCCGTCCACCAAACACTACGTGACGAGCTAA
  
  Clone variation with respect to NM_030912.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_030912 unedited
  TATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCGGCTCCGGACGGACCCCC
  GGGGCTGGGGAGTCGGGGAGGCCTGCCCCGGCCCCCTGCCCGCGGCCGCCATGGCGGAGA
  ATTGGAAGAACTGCTTCGAGGAGGAGCTCATCTGCCCTATCTGCCTGCACGTTTTCGTGG
  AGCCAGTGCAGCTGCCGTGCAAACACAACTTCTGCCGGGGCTGCATCGGCGAGGCGTGGG
  CCAAGGACAGCGGCCTCGTACGCTGCCCAGAGTGCAACCAGGCCTACAACCAGAAGCCGG
  GCCTGGAGAAGAACCTGAAGCTCACCAACATCGTGGAGAAGTTCAATGCCCTGCACGTGG
  AGAAGCCGCCGGCGGCGCTGCACTGCGTGTTCTGCCGCCGCGGCCCCCCGCTGCCCGCGC
  AGAAGGTCTGCCTGCGCTGCGAGGCGCCCTGCTGCCAGTCCCACGTGCAGACGCACCTGC
  AGCAGCCCTCCACCGCCCGCGGGCACCTCCTGGTGGAGGCGGACGACGTGCGGGCCTGGA
  GCTGCCCGCAGCACAACGCCTACCGCCTCTACCACTGCGAGGCCGAGCAGGTGGCCGTGT
  GCCAGTACTGCTGCTACTACAGCGGCGCGCATCANGGACACTCGGTGTGCGACGTGGAGA
  TCCGAAGGAATGAAATCCGGAAGATGCTCATGAAGCANCANGACCGGCTGGAGGAGCGAG
  AGCAGGACATTGAGGACCAGCTGTACAAACTCGAGTCAGCAAGCGCCTGGTGGANGGAGA
  AGTGACCACTGGGGAAGGAAGTCGGCTGCAGTACGAGAACTGCACCGCTGCTGGACGAGG
  ACTGCGCAACANGGGNAGGTCTAAACAGGCCCAGCCCAGTCTGCACGAACNCCACGCAGC
  GCTCCCTTGGGGAGCCATGCAGAGGCAAAACTGCTGGCTCTGCACTGTCTGATAAACGAG
  GAGATA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_030912 unedited
  NGGGTGGTTNNGGGNNNNNNNNTTATTTAATTNNNATGGTTTGTCATCTTTATTCCCCTT
  GTTGTTATNATAATTTTATTATTTGCTTTTGCTGTGGTCACTATCATTGGCGAAGTTCCT
  TTTCCCCTTTCCTGGGACTAGGGGTCCTGTCTTTAAAAGATCCACTCTGAGCTGAAGTGC
  CAAAACTGCTTGAGAATGGCCTTTGAACTCCGTCTGGGAAGATGGTGAGGAGAAGGAAGC
  AGGAGAAATCATTCTTGGTTTAAAAAAATTTAAAAAAACAAAAACAAAAGTCGCACAATC
  TAAAGGTCATTCCTTACTCGATCAGTGATCAAACTGCCCAAAAGGAAAACAAGAGGAGAA
  ACAAGCCCGGGGCCCTGGGCGTTCCTCCCGGGTGGGGTAAGAAGGGTGGGACCCCCAAGC
  TTTCAGGGAAGCCGAGGTTCCTTCCAGCCACGGGGGTGTGAAGGGGAAGGAGTAGAGGAA
  AAAAGGAGAAACAGAGAGAGAGCTCAGCGCCTTGACACAGACACTTTCCCATCTCCAGGG
  CCACCTGCCGTCCTGGCCCAAGCCAGCTCCCACTGTCACCTCTGCGTCCAGGAGATTCAT
  AATAAAAAAAAATCAAAAACAAAGCCCAAAACCAAAACAAAATCCAAAAAGGAAAATCAC
  CTGGGGCCAATGGCAATGAACGACACAAGGGCACGCCGACGGAACGGTATAACGCGCACG
  TTCTCTTGGCTGGCATCACCCCCCCCAACCCCGGGGGGCCTGGGGGAGGCAAAAATTCCC
  CCACCCGACCCCCCCTCCCCTGCCTTGGGCGCTTACCCCTCCCTCCCCCTACCTCCTCTC
  GCTCGGACCCGCTTTTCCCCATTCACTCCCCCCGCACTCAAATCCTTCGGTGGCGCCCGG
  TCCTGTCTTCCGGAGAGCCTTCACAAACCTTATCCTTCTTCCACCCACCCACTCCTCGCC
  CCAAGAGCACTACGTCGGAACTGAGATAGATG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_030912
• ORF Size: 1656 bp
• Insert Size: 2330
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_030912.1, NP_112174.1
• RefSeq Size: 2645
• RefSeq ORF: 1656
• Locus ID: 81603
• Domains: RING
• Gene Summary: This gene encodes a member of the tripartite motif (TRIM) protein family. Based on similarities to other proteins, the encoded protein is suspected to be an E3 ubiquitin-protein ligase. Regulation of this gene may be altered in some cancers. Mutations resulting in a truncated protein product have been observed in early-onset epileptic encephalopathy (EOEE). [provided by RefSeq, Sep 2016]
  Transcript Variant: This variant (1) encodes the longer isoform (1).