GGT1 (NM_013430) Human Untagged Clone

CAT#: SC109271

GGT1 (untagged)-Human gamma-glutamyltransferase 1 (GGT1), transcript variant 3


  "NM_013430" in other vectors (4)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol GGT1
Synonyms CD224; D22S672; D22S732; GGT; GGT 1; GGTD; GTG
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_013430, the custom clone sequence may differ by one or more nucleotides


ATGAAGAAGAAGTTAGTGGTGCTGGGCCTGCTGGCCGTGGTCCTGGTGCTGGTCATTGTCGGCCTCTGTC
TCTGGCTGCCCTCAGCCTCCAAGGAACCTGACAACCATGTGTACACCAGGGCTGCCGTGGCCGCGGATGC
CAAGCAGTGCTCGAAGATTGGGAGGGATGCACTGCGGGACGGTGGCTCTGCGGTGGATGCAGCCATTGCA
GCCCTGTTGTGTGTGGGGCTCATGAATGCCCACAGCATGGGCATCGGGGGTGGCCTCTTCCTCACCATCT
ACAACAGCACCACACGAAAAGCTGAGGTCATCAACGCCCGCGAGGTGGCCCCCAGGCTGGCCTTTGCCAC
CATGTTCAACAGCTCGGAGCAGTCCCAGAAGGGGGGGCTGTCGGTGGCGGTGCCTGGGGAGATCCGAGGC
TATGAGCTGGCACACCAGCGGCATGGGCGGCTGCCCTGGGCTCGCCTCTTCCAGCCCAGCATCCAGCTGG
CCCGCCAGGGCTTCCCCGTGGGCAAGGGCTTGGCGGCAGCCCTGGAAAACAAGCGGACCGTCATCGAGCA
GCAGCCTGTCTTGTGTGAGGTGTTCTGCCGGGATAGAAAGGTGCTTCGGGAGGGGGAGAGACTGACCCTG
CCGCAGCTGGCTGACACCTACGAGACGCTGGCCATCGAGGGTGCCCAGGCCTTCTACAACGGCAGCCTCA
CGGCCCAGATTGTGAAGGACATCCAGGCGGCCGGGGGCATTGTGACAGCTGAGGACCTGAACAACTACCG
TGCTGAGCTGATCGAGCACCCGCTGAACATCAGCCTGGGAGACGTGGTGCTGTACATGCCCAGTGCGCCG
CTCAGCGGGCCCGTGCTGGCCCTCATCCTCAACATCCTCAAAGGGTACAACTTCTCCCGGGAGAGCGTGG
AGAGCCCCGAGCAGAAGGGCCTGACGTACCACCGCATCGTAGAGGCTTTCCGGTTTGCCTACGCCAAGAG
GACCCTGCTTGGGGACCCCAAGTTTGTGGATGTGACTGAGGTGGTCCGCAACATGACCTCCGAGTTCTTC
GCTGCCCAGCTCCGGGCCCAGATCTCTGACGACACCACTCACCCGATCTCCTACTACAAGCCCGAGTTCT
ACACGCCGGATGACGGGGGCACTGCTCACCTGTCTGTCGTCGCAGAGGACGGCAGTGCTGTGTCCGCCAC
CAGCACCATCAACCTCTACTTTGGCTCCAAGGTCCGCTCCCCGGTCAGCGGGATCCTGTTCAATAATGAA
ATGGACGACTTCAGCTCTCCCAGCATCACCAACGAGTTTGGGGTACCCCCCTCACCTGCCAATTTCATCC
AGCCAGGGAAGCAGCCGCTCTCGTCCATGTGCCCGACGATCATGGTGGGCCAGGACGGCCAGGTCCGGAT
GGTGGTGGGAGCTGCTGGGGGCACACAGATCACCACGGCCACTGCACTGGCCATCATCTACAACCTCTGG
TTCGGCTATGACGTGAAGCGGGCCGTGGAGGAGCCCCGGCTGCACAACCAGCTTCTGCCCAACGTCACGA
CAGTGGAGAGAAACATTGACCAGGCAGTGACTGCAGCCCTGGAGACCCGGCACCATCACACCCAGATCGC
GTCCACCTTCATCGCTGTGGTGCAAGCCATCGTCCGCACGGCTGGTGGCTGGGCAGCTGCCTCGGACTCC
AGGAAAGGCGGGGAGCCTGCCGGCTACTGA


>OriGene 5' read for NM_013430 unedited
NGCGTTCANTTTTGTATACGATCCTATAGGGCGGCCGCGAATTCGCACGAGGGGTCAGAG
CTTTAAGCTGCAGCTCTGATGCCCCAGGNACCTCTCAGACCCCCCTGCCCAGAGCAGGCA
GCCCGCGGGTGCAGCCCAGAACTGTCTTCTGAGGAAGAGGTGCTCTCCTGGGCCCCCACT
GTCCCCAGGCCTCAGCAGCAAGGCAAGTGAGGTGCTGCCGTCATCCAGGCTGGACAGTTC
AGTGATTTGCCTGAGGCCCCACAGCAGGAGAACGAGAAGGCTGCCTGATCAGAGAGTCCC
TGAAGAAGATTCTGTGGCTACAGGCTTCAGCAGAGTGTGAGGGAGACCCCGGTTATTTCC
TCAGCTATTTCCACCAAATCCTCCTGTCTTTCGTGGCCAACACCCCAGGCAAGGCTTGGG
GCCCCCGTCTGCTGCTGGACGCAGAGCCATGAAGAAGAAGTTAGTGGTGCTGGGCCTGCT
GGCCGTGGTCCTGGTGCTGGTCATTGTCGGCCTCTGTCTCTGGCTGCCCTCAGCCTCCAA
GGAACCTGACAACCATGTGTACACCAGGGCTGCCGTGGCCGCGGATGCCAAGCAGTGCTC
GAAGATTGGGAGGGATGCACTGCGGGACGGTGGCTCTGCGGTGGATGCAGCCATTGCAGC
CCTGTTGTGTGTGGGGCTCATGAATGCCCACAGCATGGGCATCGGNGGTGGCCTCTTCCT
CACCATCTACAACAGCACCACACGAAAAGCTGAGGTCATCAACGCCCGCGAGGTGGCCCC
CAGGCTGGCCTTTGCCACCATGTTCAACAGCTCGNAGCAATCCCAGAAGGGGGGGGCTGT
CGGTGGCGGTGCCTGGGGAGAACCGAGGCTATGAGCTGGCACACCAGCGCATGGGCGGCT
GCCCTGGGCTCGCCTCTTCCG
>OriGene 3' read for NM_013430 unedited
GGCCGCAATCTANAGTCGAGNNNNTNTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTGGAGGGGGGAAACAGGCCACGGAGGCCCCCTGGAGCCTGGCAC
AAGGGCCTCATTTATTGGGCTGCTCTGCTGCTCACAAGGGAAACCGGTCCCCCAAAATCC
CCTTTCTGGGCCTGGGGAGTATCTTGGCCCTGGATTGGTTGGCAACCTTGTCCTCCTGGA
ACACTCAATAACCGGGAGGCTCCCCGCCTTTTCTGGAGTCCGAGGGAAGTGCCCAACCAC
CAACCGTGCGGACGATGGGTTGCACCACAACGATGAAAGGGGACCCCATCTGGGTGTGAT
GGGGCCGGGTCTTCAGGGCTGGAGACACTGGCTGGGCAATGGTTCTCTCCCCTGTCGAGA
CCTTGGGCAAAAACTGGTTGTGCAACCGGGGCTTCTCCACGGGCCGCTTTACGTTATAAC
CGAACCAAAAGTTGTAAATGATGGCCACTGCACTGGGCCGTGTGATCTGTGTGCCCCCAA
AAGTTTCCACCACCATACGGACCTTGCCGTTCCTGCCCCACCATGAACGTCGGGCACATG
GACCAAAGCGGCTGCTTTCCCTGCTGGAAGAAAATGGGCAGGGAGGGGGGTCCCCCCAAC
TCTTTGGTGAAGCCTGGAAAAGCTGAANTCCCCCTTTCATTATTTGAACAAGACTCCGCT
GACCGGGGACCGGGCCCTTGGACCCAAAATAAAGTGTAATGTGTCTTTTGGGGGAACAAA
AATTGCGGTCTTTTGGAAAAAAAAAGGGGAAAAATGCCCCGCTATCCGGGTGGTAAACTT
CGGCTTTATAAGAAATCGGGGAAGGGGGTCTCAAAAATTGGGCCCGGACTTGCACCAAAA
ACCGGAGGTTTTTTGGGACCCCTAATTCATTCCAACTTGGGGGCCAAACAGGTCTCTGGG
TAGCAACCGAAACCTTAAAGGGGGGACCAAGCCTCTTTTTGGGTTTCCACTTCCGGAGAT
GACCCTTAGA
Restriction Sites NotI-NotI     
ACCN NM_013430
Insert Size 2440 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_013430.2, NP_038347.2
RefSeq Size 2381 bp
RefSeq ORF 1710 bp
Locus ID 2678
Cytogenetics 22q11.23
Domains G_glu_transpept
Protein Families Protease, Transmembrane
Protein Pathways Arachidonic acid metabolism, Cyanoamino acid metabolism, Glutathione metabolism, Metabolic pathways, Selenoamino acid metabolism, Taurine and hypotaurine metabolism
Gene Summary 'The enzyme encoded by this gene is a type I gamma-glutamyltransferase that catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein. It is expressed in tissues involved in absorption and secretion and may contribute to the etiology of diabetes and other metabolic disorders. Multiple alternatively spliced variants have been identified. There are a number of related genes present on chromosomes 20 and 22, and putative pseudogenes for this gene on chromosomes 2, 13, and 22. [provided by RefSeq, Jan 2014]'
Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 6. Variants 2, 3, and 6 encode the same protein.

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