HNRNPC (NM_004500) Human Untagged Clone

CAT#: SC109312

HNRNPC (untagged)-Human heterogeneous nuclear ribonucleoprotein C (C1/C2) (HNRNPC), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HNRNPC
• Synonyms: C1; C2; HNRNP; HNRPC; SNRPC
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC109312 sequence for NM_004500 edited (data generated by NextGen Sequencing)
  ATGGCCAGCAACGTTACCAACAAGACAGATCCTCGCTCCATGAACTCCCGTGTATTCATT
  GGGAATCTCAACACTCTTGTGGTCAAGAAATCTGATGTGGAGGCAATCTTTTCGAAGTAT
  GGCAAAATTGTGGGCTGCTCTGTTCATAAGGGCTTTGCCTTCGTTCAGTATGTTAATGAG
  AGAAATGCCCGGGCTGCTGTAGCAGGAGAGGATGGCAGAATGATTGCTGGCCAGGTTTTA
  GATATTAACCTGGCTGCAGAGCCAAAAGTGAACCGAGGAAAAGCAGGTGTGAAACGATCT
  GCAGCGGAGATGTACGGCTCCTCTTTTGACTTGGACTATGACTTTCAACGGGACTATTAT
  GATAGGATGTACAGTTACCCAGCACGTGTACCTCCTCCTCCTCCTATTGCTCGGGCTGTA
  GTGCCCTCGAAACGTCAGCGTGTATCAGGAAACACTTCACGAAGGGGCAAAAGTGGCTTC
  AATTCTAAGAGTGGACAGCGGGGATCTTCCAAGTCTGGAAAGTTGAAAGGAGATGACCTT
  CAGGCCATTAAGAAGGAGCTGACCCAGATAAAACAAAAAGTGGATTCTCTCCTGGAAAAC
  CTGGAAAAAATTGAAAAGGAACAGAGCAAACAAGCAGTAGAGATGAAGAATGATAAGTCA
  GAAGAGGAGCAGAGCAGCAGCTCCGTGAAGAAAGATGAGACTAATGTGAAGATGGAGTCT
  GAGGGGGGTGCAGATGACTCTGCTGAGGAGGGGGACCTACTGGATGATGATGATAATGAA
  GATCGGGGGGATGACCAGCTGGAGTTGATCAAGGATGATGAAAAAGAGGCTGAGGAAGGA
  GAGGATGACAGAGACAGCGCCAATGGCGAGGATGACTCTTAA
  
  Clone variation with respect to NM_004500.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004500 unedited
  GGTCACCATTTGTATACGACTCCTATAGGCGGCCGCGCAATTCGCACGAGGTTGTGGCCG
  CGTTGCCGACCTCCAGCAGCAGTCGGCTTCTCTACGCAGAACCCGGGAGTAGGAGACTCA
  GAATCGAATCTCTTCTCCCTCCCCTTCTTGTGAGAGTTTTTTGATCTTCAGCTACATTTT
  CGGCTTTGTGAGAAACCTTACCATCAAACACGATGGCCAGCAACGTTACCAACAAGACAG
  ATCCTCGCTCCATGAACTCCCGTGTATTCATTGGGAATCTCAACACTCTTGTGGTCAAGA
  AATCTGATGTGGAGGCAATCTTTTCGAAGTATGGCAAAATTGTGGGCTGCTCTGTTCATA
  AGGGCTTTGCCTTCGTTCAGTATGTTAATGAGAGAAATGCCCGGGCTGCTGTAGCAGGAG
  AGGATGGCAGAATGATTGCTGGCCAGGTTTTAGATATTAACCTGGCTGCAGAGCCAAAAG
  TGAACCGAGGAAAAGCAGGTGTGAAACGATCTGCAGCGGAGATGTACGGCTCCTCTTTTG
  ACTTGGACTATGACTTTCAACGGGACTATTATGATAGGATGTACAGTTACCCAGCACGTG
  TACCTCCTCCTCCTCCTATTGCTCGGGCTGTAGTGCCCTCGAAACGTCAGCGTGTATCAG
  GAAACACTTCACGACAGGGCAAAAGTGGCTTCAATTCTAAGAGTGGACAGCGGGGATCTT
  CCAAGTCTGGAAAGTTGAAAGGAGATGACCTTCAGGCCATTAAGAAGAGCTGACCCATAT
  AAACTACAAGTGGATTCTCTCCTGGCAAACCCTGGAACAAATGTAAAAGGAACAGAGCTA
  ACTAGCTGTAGAGATGAAGAATGATCAGTCCGAGGAGTAGCTGAGCAGCAGCTCCGTGAA
  GCAAGAGAN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004500 unedited
  GACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTAAAAACCATACAT
  CCTTTTTATTGTTAAGTCATAAAGAGGTATCAAAATTAAAAGCAAAAATTACAGGGTAAG
  ACTTAACAAAACTACTAGGAGCGTCAAAGGAAGTGAAAATGGGACTAGGCGCGGGGCAAT
  ATGAATTAATGAACATGGGAAGGACAAGGATGGGGAGAACAGTGAGCATGTGCTGAAGAT
  ACTAGGGGAGAGGATCTGGTGAAAAATTTGATCTTAGACAAGCGCCTAGGTAAAGAAATA
  ATGGGATAAGATTTCTAAACCCCACTATGTGCTTAAGAGTCATCCTCGCCATTGGCGCTG
  TCTCTGTCATCCTCTCCTTCCTCAGCCTCTTTTTCATCATCCTTGATCAACTCCAGCTGG
  TCATCCCCCCGATCTTCATTATCATCATCATCCAGTAGGTCCCCCTCCTCAGCAGAGTCA
  TCTGCACCCCCCTCAGACTCCATCTTCACATTAGTCTCATCTTTCTTCACGGAGCTGCTG
  CTCTGCTCCTCTTCTGACTTATCATTCTTCATCTCTACTGCTTGTTTGCTCTGTTCCTTT
  TCAATTTTTTCCAGGTTTTCCAGGAGAGAATCCACTTTTTGTTTTATCTGGGTCAGCTCC
  TTCTTAATGGCCTGANAGTCATCTCCTTTCAACTTTCCAGACTTGGAAGATCCCCGCTGT
  CCACTCTTAGAATTGAGCCACTTTTGCCCCTTCGTGAAGTGTTTCCTGATACACGCTGAC
  GTTTCGAGGGCACTACAGCCCGAGCAATAGAGGAGGGAGAGTACACGTGCTGGGTAACTG
  TACATCCTATCATAATAGTCCNGTTGAAAGTATAGTCCAGTCAAAGAAGACCCGACATCT
  CGTG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004500
• Insert Size: 1350 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004500.2, NP_004491.1
• RefSeq Size: 1732 bp
• RefSeq ORF: 873 bp
• Locus ID: 3183
• Cytogenetics: 14q11.2
• Domains: RRM
• Protein Pathways: Spliceosome
• Gene Summary: 'This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (2) lacks an alternate in-frame segment compared to variant 1. The resulting isoform (b, also known as isoform C1) has the same N- and C-termini but is shorter compared to isoform a. Variants 2 and 4 both encode isoform b.