hnRNP K (HNRNPK) (NM_031263) Human Untagged Clone

CAT#: SC109316

HNRNPK (untagged)-Human heterogeneous nuclear ribonucleoprotein K (HNRNPK), transcript variant 2


  "NM_031263" in other vectors (6)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol HNRNPK
Synonyms AUKS; CSBP; HNRPK; TUNP
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC109316 sequence for NM_031263 edited (data generated by NextGen Sequencing)
ATGGAAACTGAACAGCCAGAAGAAACCTTCCCTAACACTGAAACCAATGGTGAATTTGGT
AAACGCCCTGCAGAAGATATGGAAGAGGAACAAGCATTTAAAAGATCTAGAAACACTGAT
GAGATGGTTGAATTACGCATTCTGCTTCAGAGCAAGAATGCTGGGGCAGTGATTGGAAAA
GGAGGCAAGAATATTAAGGCTCTCCGTACAGACTACAATGCCAGTGTTTCAGTCCCAGAC
AGCAGTGGCCCCGAGCGCATATTGAGTATCAGTGCTGATATTGAAACAATTGGAGAAATT
CTGAAGAAAATCATCCCTACCTTGGAAGAGGGCCTGCAGTTGCCATCACCCACTGCAACC
AGCCAGCTCCCGCTCGAATCTGATGCTGTGGAATGCTTAAATTACCAACACTATAAAGGA
AGTGACTTTGACTGCGAGTTGAGGCTGTTGATTCATCAGAGTCTAGCAGGAGGAATTATT
GGGGTCAAAGGTGCTAAAATCAAAGAACTTCGAGAGAACACTCAAACCACCATCAAGCTT
TTCCAGGAATGCTGTCCTCATTCCACTGACAGAGTTGTTCTTATTGGAGGAAAACCCGAT
AGGGTTGTAGAGTGCATAAAGATCATCCTTGATCTTATATCTGAGTCTCCCATCAAAGGA
CGTGCACAGCCTTATGATCCCAATTTTTACGATGAAACCTATGATTATGGTGGTTTTACA
ATGATGTTTGATGACCGTCGCGGACGCCCAGTGGGATTTCCCATGCGGGGAAGAGGTGGT
TTTGACAGAATGCCTCCTGGTCGGGGTGGGCGTCCCATGCCTCCATCTAGAAGAGATTAT
GATGATATGAGCCCTCGTCGAGGACCACCTCCCCCTCCTCCCGGACGAGGCGGCCGGGGT
GGTAGCAGAGCTCGGAATCTTCCTCTTCCTCCACCACCACCACCTAGAGGGGGAGACCTC
ATGGCCTATGACAGAAGAGGGAGACCTGGAGACCGTTACGACGGCATGGTTGGTTTCAGT
GCTGATGAAACTTGGGACTCTGCAATAGATACATGGAGCCCATCAGAATGGCAGATGGCT
TATGAACCACAGGGTGGCTCCGGATATGATTATTCCTATGCAGGGGGTCGTGGCTCATAT
GGTGATCTTGGTGGACCTATTATTACTACACAAGTAACTATTCCCAAAGATTTGGCTGGA
TCTATTATTGGCAAAGGTGGTCAGCGGATTAAACAAATCCGTCATGAGTCGGGAGCTTCG
ATCAAAATTGATGAGCCTTTAGAAGGATCCGAAGATCGGATCATTACCATTACAGGAACA
CAGGACCAGATACAGAATGCACAGTATTTGCTGCAGAACAGTGTGAAGCAGTATGCAGAT
GTTGAAGGATTCTAA

Clone variation with respect to NM_031263.2
>OriGene 5' read for NM_031263 unedited
AATTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCTGAGGCGGCG
CGGCAGCGGAGGGACGGCAGTCTCGCGCGGCTACTGCAGCACTGGGGTGTCAGTTGTTGG
TCCGACCCAGAACGCTTCAGTTCTGCTCTGCAAGGATATATAATAACTGATTGGTGTGCC
CGTTTAATAAAAGAATATGGAAACTGAACAGCCAGAAGAAACCTTCCCTAACACTGAAAC
CAATGGTGAATTTGGTAAACGCCCTGCAGAAGATATGGAAGAGGAACAAGCATTTAAAAG
ATCTAGAAACACTGATGAGATGGTTGAATTACGCATTCTGCTTCAGAGCAAGAATGCTGG
GGCAGTGATTGGAAAAGGAGGCAAGAATATTAAGGCTCTCCGTACAGACTACAATGCCAG
TGTTTCAGTCCCAGACAGCAGTGGCCCCGAGCGCATATTGAGTATCAGTGCTGATATTGA
AACAATTGGAGAAATTCTGAAGAAAATCATCCCTACCTTGGAAGAGGGCCTGCAGTTGCC
ATCACCCACTGCAACCAGCCAGCTCCCGCTCGAATCTGATGCTGTGGAATGCTTAAATTA
CCAACACTATAAAGGAAGTGACTTTGACTGCGAGTTGAGGCTGTTGATTCATCAGAGTCT
AGCAGGAGGAATTATTGGGGTCAAAGGTGCTAAAATCAAAGAACTTCGAGAGAACACTCA
AACCACCTTCAAGCTTTTCCAGGAAACCTGTCCTCATTCCACTGACAGAGTTGTTCTTAT
TGAAGGACACCCGAATAGGTTGAAAAGTGCATAAAAACATCCTTGATCTATATCTGAGTC
TCCCATCAAAGGACTGCCCCACCTTT
>OriGene 3' read for NM_031263 unedited
TTGGCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTACATAAGATTACTA
TATTTCCTTTTAAGAGGAACGTTTCAACAAATTTTACAGGTGTCAATCAACCCTTGTTCA
AATCGGGCACACATCAAATCTAGCATCATGGGTGTTTTATTTATTTGGAAGTGAATTTTA
ACTATCAATACAAATGCCAAGATACTACACAAAACATCCACAGGAACTTTTTTCATCTTT
TTTTTTTTTGAATTGTACACAAACATTTCCTACATAATCCAACATACAACAGAGAAATGG
TACATCTTTTTCTTTCAATTTGCATACAATGGAAAAACAAGTATATATATATTTTACAAA
GTTTAACTAATAAGACACTAGAGCAAATTGACAGTTTAAGTCTATAGGTGAGAAATTATC
TAATAAAAATAATCAATTTTTTCAGCATTAGTCACTTCCATAACCAAGTGTTATTCTGAT
TAATAAAACTTGCTGCCAATCAGAATTCTGGTATATACTCATACCATTACTCAACTTGTA
GTACTGCTCCCCACCTTAGTTCTTCACAACTAACATAGAAAATTGTTGAAAAGTAGGGGC
AAGCATTTGCAAAAACAAACAAAAAATCCCCAGCTTATTATAAGCATGAATATGTATGAT
GGAATTTCTTCCCAGCAATAGACTTCCAAACCATCAAGAAATCACCAGAACTAAGTTTGC
CAAGTTATTTTGCCTATGTCNCAACAGAGATGCACTTATATGTCCAACAGAGGAGCTGAA
ATTAAACTTAGTGTTAGTTGGNGGTGGNGGTTGGGAATATCAANCCCCATTTTAAAATGA
CTGTCTTAAAAAAAATGACCACCAAAATAGGTCACTAAATTTATTTAAAATCATAAACGT
TCCTACAAAGACATTACATCTTGACCTGCTTGGACAGATGCAGGAACTGGGACTATGTTA
CTTTCCTCCTGTCCACCCCAATGTACAGA
Restriction Sites NotI-NotI     
ACCN NM_031263
Insert Size 2770 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_031263.1, NP_112553.1
RefSeq Size 2745 bp
RefSeq ORF 1395 bp
Locus ID 3190
Cytogenetics 9q21.32
Domains KH
Protein Pathways Spliceosome
Gene Summary 'This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized. [provided by RefSeq, Jul 2008]'
Transcript Variant: This variant (2) uses an alternate 5' non-coding exon, hence has a different 5' UTR compared to transcript variant 1. Transcript variants 1 and 2 encode the same isoform (a).

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