HOXC6 (NM_153693) Human Untagged Clone

CAT#: SC109320

HOXC6 (untagged)-Human homeobox C6 (HOXC6), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HOXC6
• Synonyms: CP25; HHO.C8; HOX3; HOX3C
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC109320 sequence for NM_153693 edited (data generated by NextGen Sequencing)
  ATGCTCTCAAACTGCAGACAAAACACCTTAGGACATAACACACAGACCTCAATCGCTCAG
  GATTTTAGTTCTGAGCAGGGCAGGACTGCGCCCCAGGACCAGAAAGCCAGTATCCAGATT
  TACCCCTGGATGCAGCGAATGAATTCGCACAGTGGGGTCGGCTACGGAGCGGACCGGAGG
  CGCGGCCGCCAGATCTACTCGCGGTACCAGACCCTGGAACTGGAGAAGGAATTTCACTTC
  AATCGCTACCTAACGCGGCGCCGGCGCATCGAGATCGCCAACGCGCTTTGCCTGACCGAG
  CGACAGATCAAAATCTGGTTCCAGAACCGCCGGATGAAGTGGAAAAAAGAATCTAATCTC
  ACATCCACTCTCTCGGGGGGCGGCGGAGGGGCCACCGCCGACAGCCTGGGCGGAAAAGAG
  GAAAAGCGGGAAGAGACAGAAGAGGAGAAGCAGAAAGAGTGA
  
  Clone variation with respect to NM_153693.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_153693 unedited
  TCAAATTTTGTAATACGACTCACTATTAGGGCGGCCGCGAATTCGCACGAGGGGACGTCC
  TCCCCACGTCGCCCTCAATTCCACCGCCTATGATCCAGTGAGGCATTTCTCGACCTATGG
  AGCGGCCGTTGCCCAGAACCGGATCTACTCGACTCCCTTTTATTCGCCACAGGAGAATGT
  CGTGTTCAGTTCCAGCCGGGGGCCGTATGACTATGGATCTAATTCCTTTTACCAGGAGAA
  AGACATGCTCTCAAACTGCAGACAAAACACCTTAGGACATAACACACAGACCTCAATCGC
  TCAGGATTTTAGTTCTGAGCAGGGCAGGACTGCGCCCCAGGACCAGAAAGCCAGTATCCA
  GATTTACCCCTGGATGCAGCGAATGAATTCGCACAGTGGGGTCGGCTACGGAGCGGACCG
  GAGGCGCGGCCGCCAGATCTACTCGCGGTACCAGACCCTGGAACTGGAGAAGGAATTTCA
  CTTCAATCGCTACCTAACGCGGCGCCGGCGCATCGAGATCGCCAACGCGCTTTGCCTGAC
  CGAGCGACAGATCAAAATCTGGTTCCAGAACCGCCGGATGAAGTGGAAAAAAGAATCTAA
  TCTCACATCCACTCTCTCGGGGGGCGGCGGAGGGGCCACCGCCGACAGCCTGGGCGGAAA
  AGAGGAAAAGCGGGAAGAGACAGAAGAGGAGAAGCAGAAAGAGTGACCAGGACTGGTCCC
  TGCCACCCCTCTCTCCCTTTCTCCCTCGCTCCCCACCAACTCTCCCCTTATCACACACTC
  TGTATTTATCACTGGCACAATTGATGTGTTTTGATTCCCTAAACAAAATANGGAGTCAAA
  CGTGGACCCTGAAGTCAGCTTTGGACCCCCTNCTCACCGNACAACTNTNTTTACCACGCG
  CCTNCTNCTNCTNGNTCCTTGNNTAGCTCGTCTCGCTTGCTACAGGCCTTNTNCCCGTCA
  GNNNCTGGGGCTCGACCTGACTN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_153693 unedited
  TTTTTTTTTTTTTTTGTAATTTTCCCTCTTTTTTTTCCTTTTTGAAATTGGAAGGAACAC
  TGACGGTGCTAAACATAAATATAAATACAGAGACCACAAATACAGCTAAAAATCTTCACA
  CAGAAACGGTCACAGTTTGTAAAATGCCATAATGACCCCCAGGATTCTTTAAATACAATT
  TGCCTGGGCTGGGCATTTGCTGGGGCAGAGGGGCTAGGCAGGGACTGCGGGGAGGCCCTG
  GGGGTTGGTGTGGGGCCAAGGCGCGCCCTCCTTGGGCCTCCGGCCCTCCCCGGCTGCCAG
  GCCGGGCCCTGAGGCCCTGGAGCAGAGGCCCCAGCAGGCCCAGGGGCCGGCTCTCTGCAC
  GGGGGGCGGGGGTGGGGGCGTCNNAAGAGTGGGGGAGCCAAGTCCTCACTTGGAGGGCAA
  TCTGTAGAGTCTGAGTTCAGGGTCCGAGCCCCCAAGGCCTGGACGGGGAAAAGGGCCTGT
  AGACAAGCCGAGAACGAGCTA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_153693
• Insert Size: 1430 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_153693.1, NP_710160.1
• RefSeq Size: 1869 bp
• RefSeq ORF: 462 bp
• Locus ID: 3223
• Cytogenetics: 12q13.13
• Domains: homeobox
• Protein Families: Transcription Factors
• Gene Summary: 'This gene belongs to the homeobox family, members of which encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC6, is one of several HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Alternatively spliced transcript variants encoding different isoforms have been identified for HOXC6. Transcript variant two includes the shared exon, and transcript variant one includes only gene-specific exons. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (2) uses an alternate 5' exon structure and thus differs in the 5' UTR 5' coding region. These difference cause translation initiation at a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus than isoform 1.