MRP1 (ABCC1) (NM_004996) Human Untagged Clone

CAT#: SC109450

ABCC1 (untagged)-Human ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (ABCC1), transcript variant 1


  "NM_004996" in other vectors (6)

Reconstitution Protocol

USD 3,100.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol ABCC1
Synonyms ABC29; ABCC; GS-X; MRP; MRP1
Vector pCMV6-XL6
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_004996 edited
GGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCATTTAGGTGACACTATAGAATACA
AGCTACTTGTTCTTTTTGCAGCGGCCGCGAATTCGGCACGAGGCGGGCCCGATCACCCGC
CGCCCGGTGCCCGCCGCCGCCCGCGCCAGCAACCGGGCCCGATCACCCGCCGCCCGGTGC
CCGCCGCCGCCCGCGCCACCGGCATGGCGCTCCGGGGCTTCTGCAGCGCCGATGGCTCCG
ACCCGCTCTGGGACTGGAATGTCACGTGGAATACCAGCAACCCCGACTTCACCAAGTGCT
TTCAGAACACGGTCCTCGTGTGGGTGCCTTGTTTTTACCTCTGGGCCTGTTTCCCCTTCT
ACTTCCTCTATCTCTCCCGACATGACCGAGGCTACATTCAGATGACACCTCTCAACAAAA
CCAAAACTGCCTTGGGATTTTTGCTGTGGATCGTCTGCTGGGCAGACCTCTTCTACTCTT
TCTGGGAAAGAAGTCGGGGCATATTCCTGGCCCCAGTGTTTCTGGTCAGCCCAACTCTCT
TGGGCATCACCATGCTGCTTGCTACCTTTTTAATTCAGCTGGAGAGGAGGAAGGGAGTTC
AGTCTTCAGGGATCATGCTCACTTTCTGGCTGGTAGCCCTAGTGTGTGCCCTAGCCATCC
TGAGATCCAAAATTATGACAGCCTTAAAAGAGGATGCCCAGGTGGACCTGTTTCGTGACA
TCACTTTCTACGTCTACTTTTCCCTCTTACTCATTCAGCTCGTCTTGTCCTGTTTCTCAG
ATCGCTCACCCCTGTTCTCGGAAACCATCCACGACCCTAATCCCTGCCCAGAGTCCAGCG
CTTCCTTCCTGTCGAGGATCACCTTCTGGTGGATCACAGGGTTGATTGTCCGGGGCTACC
GCCAGCCCCTGGAGGGCAGTGACCTCTGGTCCTTAAACAAGGAGGACACGTCGGAACAAG
TCGTGCCTGTTTTGGTAAAGAACTGGAAGAAGGAATGCGCCAAGACTAGGAAGCAGCCGG
TGAAGGTCGTGTACTCCTCCAAGGATCCTGCCCAGCCGAAAGAGAGTTCCAAGGTGGATG
CGAATGAGGAGGTGGAGGCTTTGATCGTCAAGTCCCCACAGAAGGAGTGGAACCCCTCTC
TGTTTAAGGTGTTATACAAGACCTTTGGGCCCTACTTCCTCATGAGCTTCTTCTTCAAGG
CCATCCACGACCTGATGATGTTTTCCGGGCCGCAGATCTTAAAGTTGCTCATCAAGTTCG
TGAACGACACGAAGGCCCCAGACTGGCAGGGCTACTTCTACACCGTGCTGCTGTTTGTCA
CTGCCTGCCTGCAGACCCTCGTGCTGCACCAGTACTTCCACATCTGCTTCGTCAGTGGCA
TGAGGATCAAGACCGCTGTCATTGGGGCTGTCTATCGGAAGGCCCTGGTGATCACCAATT
CAGCCAGAAAATCCTCCACGGTCGGGGAGATTGTCAACCTCATGTCTGTGGACGCTCAGA
GGTTCATGGACTTGGCCACGTACATTAACATGATCTGGTCAGCCCCCCTGCAAGTCATCC
TTGCTCTCTACCTCCTGTGGCTGAATCTGGGCCCTTCCGTCCTGGCTGGAGTGGCGGTGA
TGGTCCTCATGGTGCCCGTCAATGCTGTGATGGCGATGAAGACCAAGACGTATCAGGTGG
CCCACATGAAGAGCAAAGACAATCGGATCAAGCTGATGAACGAAATTCTCAATGGGATCA
AAGTGCTAAAGCTTTATGCCTGGGAGCTGGCATTCAAGGACAAGGTGCTGGCCATCAGGC
AGGAGGAGCTGAAGGTGCTGAAGAAGTCTGCCTACCTGTCAGCCGTGGGCACCTTCACCT
GGGTCTGCACGCCCTTTCTGGTGGCCCTGTGCACATTTGCCGTCTACGTGACCATTGACG
AGAACAACATCCTGGATGCCCAGACAGCCTTCGTGTCTTTGGCCTTGTTCAACATCCTCC
GGTTTCCCCTGAACATTCTCCCCATGGTCATCAGCAGCATCGTGCAGGCGAGTGTCTCCC
TCAAACGCCTGAGGATCTTTCTCTCCCATGAGGAGCTGGAACCTGACAGCATCGAGCGAC
GGCCTGTCAAAGACGGCGGGGGCACGAACAGCATCACCGTGAGGAATGCCACATTCACCT
GGGCCAGGAGCGACCCTCCCACACTGAATGGCATCACCTTCTCCATCCCCGAAGGTGCTT
TGGTGGCCGTGGTGGGCCAGGTGGGCTGCGGAAAGTCGTCCCTGCTCTCAGCCCTCTTGG
CTGAGATGGACAAAGTGGAGGGGCACGTGGCTATCAAGGGCTCCGTGGCCTATGTGCCAC
AGCAGGCCTGGATTCAGAATGATTCTCTCCGAGAAAACATCCTTTTTGGATGTCAGCTGG
AGGAACCATATTACAGGTCCGTGATACAGGCCTGTGCCCTCCTCCCAGACCTGGAAATCC
TGCCCAGTGGGGATCGGACAGAGATTGGCGAGAAGGGCGTGAACCTGTCTGGGGGCCAGA
AGCAGCGCGTGAGCCTGGCCCGGGCCGTGTACTCCAACGCTGACATTTACCTCTTCGATG
ATCCCCTCTCAGCAGTGGATGCCCATGTGGGAAAACACATCTTTGAAAATGTGATTGGCC
CCAAGGGGATGCTGAAGAACAAGACGCGGATCTTGGTCACGCACAGCATGAGCTACTTGC
CGCAGGTGGACGTCATCATCGTCATGAGTGGCGGCAAGATCTCTGAGATGGGCTCCTACC
AGGAGCTGCTGGCTCGAGACGGCGCCTTCGCTGAGTTCCTGCGTACCTATGCCAGCACAG
AGCAGGAGCAGGATGCAGAGGAGAACGGGGTCACGGGCGTCAGCGGTCCAGGGAAGGAAG
CAAAGCAAATGGAGAATGGCATGCTGGTGACGGACAGTGCAGGGAAGCAACTGCAGAGAC
AGCTCAGCAGCTCCTCCTCCTATAGTGGGGACATCAGCAGGCACCACAACAGCACCGCAG
AACTGCAGAAAGCTGAGGCCAAGAAGGAGGAGACCTGGAAGCTGATGGAGGCTGACAAGG
CGCAGACAGGGCAGGTCAAGCTTTCCGTGTACTGGGACTACATGAAGGCCATCGGACTCT
TCATCTCCTTCCTCAGCATCTTCCTTTTCATGTGTAACCATGTGTCCGCGCTGGCTTCCA
ACTATTGGCTCAGCCTCTGGACTGATGACCCCATCGTCAACGGGACTCAGGAGCACACGA
AAGTCCGGCTGAGCGTCTATGGAGCCCTGGGCATTTCACAAGGGATCGCCGTGTTTGGCT
ACTCCATGGCCGTGTCCATCGGGGGGATCTTGGCTTCCCGCTGTCTGCACGTGGACCTGC
TGCACAGCATCCTGCGGTCACCCATGAGCTTCTTTGAGCGGACCCCCAGTGGGAACCTGG
TGAACCGCTTCTCCAAGGAGCTGGACACAGTGGACTCCATGATCCCGGAGGTCATCAAGA
TGTTCATGGGCTCCCTGTTCAACGTCATTGGTGCCTGCATCGTTATCCTGCTGGCCACGC
CCATCGCCGCCATCATCATCCCGCCCCTTGGCCTCATCTACTTCTTCGTCCAGAGGTTCT
ACGTGGCTTCCTCCCGGCAGCTGAAGCGCCTCGAGTCGGTCAGCCGCTCCCCGGTCTATT
CCCATTTCAACGAGACCTTGCTGGGGGTCAGCGTCATTCGAGCCTTCGAGGAGCAGGAGC
GCTTCATCCACCAGAGTGACCTGAAGGTGGACGAGAACCAGAAGGCCTATTACCCCAGCA
TCGTGGCCAACAGGTGGCTGGCCGTGCGGCTGGAGTGTGTGGGCAACTGCATCGTTCTGT
TTGCTGCCCTGTTTGCGGTGATCTCCAGGCACAGCCTCAGTGCTGGCTTGGTGGGCCTCT
CAGTGTCTTACTCATTGCAGGTCACCACGTACTTGAACTGGCTGGTTCGGATGTCATCTG
AAATGGAAACCAACATCGTGGCCGTGGAGAGGCTCAAGGAGTATTCAGAGACTGAGAAGG
AGGCGCCCTGGCAAATCCAGGAGACAGCTCCGCCCAGCAGCTGGCCCCAGGTGGGCCGAG
TGGAATTCCGGAACTACTGCCTGCGCTACCGAGAGGACCTGGACTTCGTTCTCAGGCACA
TCAATGTCACGATCAATGGGGGAGAAAAGGTCGGCATCGTGGGGCGGACGGGAGCTGGGA
AGTCGTCCCTGACCCTGGGCTTATTTCGGATCAACGAGTCTGCCGAAGGAGAGATCATCA
TCGATGGCATCAACATCGCCAAGATCGGCCTGCACGACCTCCGCTTCAAGATCACCATCA
TCCCCCAGGACCCTGTTTTGTTTTCGGGTTCCCTCCGAATGAACCTGGACCCATTCAGCC
AGTACTCGGATGAAGAAGTCTGGACGTCCCTGGAGCTGGCCCACCTGAAGGACTTCGTGT
CAGCCCTTCCTGACAAGCTAGACCATGAATGTGCAGAAGGCGGGGAGAACCTCAGTGTCG
GGCAGCGCCAGCTTGTGTGCCTAGCCCGGGCCCTGCTGAGGAAGACGAAGATCCTTGTGT
TGGATGAGGCCACGGCAGCCGTGGACCTGGAAACGGACGACCTCATCCAGTCCACCATCC
GGACACAGTTCGAGGACTGCACCGTCCTCACCATCGCCCACCGGCTCAACACCATCATGG
ACTACACAAGGGTGATCGTCTTGGACAAAGGAGAAATCCAGGAGTACGGCGCCCCATCGG
ACCTCCTGCAGCAGAGAGGTCTTTTCTACAGCATGGCCAAAGACGCCGGCTTGGTGTGAG
CCCCAGAGCTGGCATATCTGGTCAGAACTGCAGGGCCTATATGCCAGCGCCCAGGGAGGA
GTCAGTACCCCTGGTAAACCAAGCCTCCCACACTGAAACCAAAACATAAAAACCAAACCC
AGACAACCAAAACATATTCAAAGCAGCAGCCACCGCCATCCGGTCCCCTGCCTGGAACTG
GCTGTGAAGACCCAGGAGAGACAGAGATGCGAACCACCCAAAACACGCACACCCTGCCCC
TGGTGCCCTGAGACAGACACACAGCCTCACGCCCCCAGGAATGCAAGTGGTTTCCTGGTG
CTTCCCACGGAGGAGTTTTGGCAGCCAGACTTCTGGAGGAATTGGTTGTATAGAAGATCC
TAGTGACCAAATTCAGCCTACTGCCTCGGATCTCTCCAGCCGAAGTCTGTGGACTGCAAG
TCTTTGAGATGCTTCTGGCTCCCATCACCTCTAACATCCTTGTCTGGGTCTACCAGGAAC
GCTTCATTTCCTTGGGGCTGCAGTTTTGTGGTTGAGGGGCCTGGAGAAAATCATTTTCTC
CTCTTGGCAGTGTCCCAGGGCCCTGGATGGTCCTCTTACCAACATCTGGTCTTCCAGGCA
CTCAAAAGCTGGGAACCAGCATCTCAGCGCCAGCTCTACCAGTTCTCGTTTTGGGCCAGA
GGCAGCCTCTGCACTCCCACGCCTGTCCTCCTGGAAGGGACCTGGTTGGACTAACGGCTA
ACCTGGACCTGGAACTGTAGGGCCAGGGGATTGTCTCAGGGCCGACGTTCCACCTGGGGC
TTCCCTCCCCACCCACCCCCACTCCAGGCTTTCCCTTTTTTCTTTTGTTCAACATTGTAA
GAACAATCAATGCTGTTATTACTGTTCCCACCATGATTGATGTGGGGTAAATATTAAGGA
GATGGCCTCATGGGAATTTGACCTTGACTAGAAATAGAGACTGAGAGTGAGCAACCAGCT
GGAAGGTACTATGCCAGTCCTAGCAGAAAAATGTGTTAGGGGCCTGGCCCAAAGCAGTGT
TGGTTGCTTACAGTGTTGATTGATTTTGTTCTTTTTTCTTACCACCTCTTTTCTTTCCCT
CTCATGGTACCTGCTCATGGTTATGAAGCTTTCAAAGTAAAGAACACGAAATACCTCCCA
AGTATTACCAGTGGGTACCAAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCGCG
GTCATAGCTGTTTCCTGAACAGATCCCGGGTGGCATCCCTGTGACCCCTCCCCAGT
Restriction Sites Please inquire     
ACCN NM_004996
Insert Size 5900 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_004996.2, NP_004987.1
RefSeq Size 5927 bp
RefSeq ORF 4596 bp
Locus ID 4363
Cytogenetics 16p13.11
Domains ABC_membrane, ABC_tran, AAA
Protein Families Druggable Genome, Transmembrane
Protein Pathways ABC transporters
Gene Summary 'The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]'

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