PTBP1 (NM_031991) Human Untagged Clone

CAT#: SC109649

PTBP1 (untagged)-Human polypyrimidine tract binding protein 1 (PTBP1), transcript variant 3


  "NM_031991" in other vectors (7)

Reconstitution Protocol

USD 760.00

4 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol PTBP1
Synonyms HNRNP-I; HNRNPI; HNRPI; pPTB; PTB; PTB-1; PTB-T; PTB2; PTB3; PTB4
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_031991, the custom clone sequence may differ by one or more nucleotides


ATGGACGGCATTGTCCCAGATATAGCCGTTGGTACAAAGCGGGGATCTGACGAGCTTTTCTCTACTTGTG
TCACTAACGGACCGTTTATCATGAGCAGCAACTCGGCTTCTGCAGCAAACGGAAATGACAGCAAGAAGTT
CAAAGGTGACAGCCGAAGTGCAGGCGTCCCCTCTAGAGTGATCCACATCCGGAAGCTCCCCATCGACGTC
ACGGAGGGGGAAGTCATCTCCCTGGGGCTGCCCTTTGGGAAGGTCACCAACCTCCTGATGCTGAAGGGGA
AAAACCAGGCCTTCATCGAGATGAACACGGAGGAGGCTGCCAACACCATGGTGAACTACTACACCTCGGT
GACCCCTGTGCTGCGCGGCCAGCCCATCTACATCCAGTTCTCCAACCACAAGGAGCTGAAGACCGACAGC
TCTCCCAACCAGGCGCGGGCCCAGGCGGCCCTGCAGGCGGTGAACTCGGTCCAGTCGGGGAACCTGGCCT
TGGCTGCCTCGGCGGCGGCCGTGGACGCAGGGATGGCGATGGCCGGGCAGAGCCCCGTGCTCAGGATCAT
CGTGGAGAACCTCTTCTACCCTGTGACCCTGGATGTGCTGCACCAGATTTTCTCCAAGTTCGGCACAGTG
TTGAAGATCATCACCTTCACCAAGAACAACCAGTTCCAGGCCCTGCTGCAGTATGCGGACCCCGTGAGCG
CCCAGCACGCCAAGCTGTCGCTGGACGGGCAGAACATCTACAACGCCTGCTGCACGCTGCGCATCGACTT
TTCCAAGCTCACCAGCCTCAACGTCAAGTACAACAATGACAAGAGCCGTGACTACACACGCCCAGACCTG
CCTTCCGGGGACAGCCAGCCCTCGCTGGACCAGACCATGGCCGCGGCCTTCGGCCTTTCCGTTCCGAACG
TCCACGGCGCCCTGGCCCCCCTGGCCATCCCCTCGGCGGCGGCGGCAGCTGCGGCGGCAGGTCGGATCGC
CATCCCGGGCCTGGCGGGGGCAGGAAATTCTGTATTGCTGGTCAGCAACCTCAACCCAGAGAGAGTCACA
CCCCAAAGCCTCTTTATTCTTTTCGGCGTCTACGGTGACGTGCAGCGCGTGAAGATCCTGTTCAATAAGA
AGGAGAACGCCCTAGTGCAGATGGCGGACGGCAACCAGGCCCAGCTGGCCATGAGCCACCTGAACGGGCA
CAAGCTGCACGGGAAGCCCATCCGCATCACGCTCTCGAAGCACCAGAACGTGCAGCTGCCCCGCGAGGGC
CAGGAGGACCAGGGCCTGACCAAGGACTACGGCAACTCACCCCTGCACCGCTTCAAGAAGCCGGGCTCCA
AGAACTTCCAGAACATATTCCCGCCCTCGGCCACGCTGCACCTCTCCAACATCCCGCCCTCAGTCTCCGA
GGAGGATCTCAAGGTCCTGTTTTCCAGCAATGGGGGCGTCGTCAAAGGATTCAAGTTCTTCCAGAAGGAC
CGCAAGATGGCACTGATCCAGATGGGCTCCGTGGAGGAGGCGGTCCAGGCCCTCATTGACCTGCACAACC
ACGACCTCGGGGAGAACCACCACCTGCGGGTCTCCTTCTCCAAGTCCACCATCTAG


>OriGene 5' read for NM_031991 unedited
NTTGTCAAAATTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACGAGGCCACTCC
GTCCCCCGCGGGTCTGCTCTGTGTGCCATGGACGGCATTGTCCCAGATATAGCCGTTGGT
ACAAAGCGGGGATCTGACGAGCTTTTCTCTACTTGTGTCACTAACGGACCGTTTATCATG
AGCAGCAACTCGGCTTCTGCAGCAAACGGAAATGACAGCAAGAAGTTCAAAGGTGACAGC
CGAAGTGCAGGCGTCCCCTCTAGAGTGATCCACATCCGGAAGCTCCCCATCGACGTCACG
GAGGGGGAGGTCATCTCCCTGGGGCTGCCCTTTGGGAAGGTCACCAACCTCCTGATGCTG
AAGGGGAAAAACCAGGCCTTCATCGAGATGAACACGGAGGAGGCTGCCAACACCATGGTG
AACTACTACACCTCGGTGACCCCTGTGCTGCGCGGCCAGCCCATCTACATCCAGTTCTCC
AACCACAAGGAGCTGAAGACCGACAGCTCTCCCAACCAGGCGCGGGCCCAGGCGGCCCTG
CAGGCGGTGAACTCGGTCCAGTCGGGGAACCTGGCCTTGGCTGCCTCGGCGGCGGCCGTG
GACGCAGGGATGGCGATGGCCGGGCAGAGCCCCGTGCTCAGGATCATCGTGGAGAACCTC
TTCTACCCTGTGACCCTGGATGTGCTGCACCAGATTTTCTCCAAGTTCGGCACAGTGTTN
GAAGATCATCACCTTCACCAAGAACAACCAGTTCCAGGCCCTGCTGCAGTATGCGGACCC
CGTGAGCGCCCAGCACGCCAAGCTGTCGCTGGACGGGCAGAACATCTACAACGCCTGCTG
CACGCTGCGCATCGACTTTTNCAGCTCACAGCCTCNACGTCAGTACAACATGACAAGAGC
CGTG
>OriGene 3' read for NM_031991 unedited
CGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTGAGGATACANAAGATTTATTC
GAAGTCCAGGTACAGACTGGCCAACCTGCCTCTACAGCGTCCACAGCGAACACAGGGCTA
GACAAGGGAGGAGTTTCTCAAACGGTTTTAATCGGTTCTCTCCGCGTCACAAGCCATCGG
GTAAGGCAACGGAATGTGCGTGGGGTCCCCTGTGGCTCCGCGGTCACAATACTGAGCCTG
GAATTGCTGTTAGCAAAATATACATTTGTGTCACCATAAAAAACCGCGCCGCCGCCCCTC
GGGTCTCACAACAGGTATAAAAAATTATAAATATTTACACCCTTGTTACACGCTTTTACG
GAAAGGGGATCCTAGGAGAGCCCCCGGGACAGGACGCGGGGGCGGTAGAAAGAGCACAGA
GAAGACAGGAGGAGCGCCCGCCTTCCGGGTCCCAGCATCAGAGGCAGGCAAAACACAGAA
ATGAGACTTTGGTCCAAAATTTGAAGGAAGAAAAAACCCTGAAGTTTGAGAGCAAGTTTT
CTAGGCGACTGCAGGTGAAGGCGTGGTGTAAGGCAACCCGAGGCGATGCCAGAGGCGGCG
ACACGCCCGCCCTTTCCCTGAAGCTCAGGNGCTCTAAGATAGGACCCGGGCTCCCTGTGC
CTGACCCACNNTGGCGNCCCGNCTGCTCTCTGGNAACTGGTCCTGCCTGTGACTTATTAC
AAGGAATAAATAAAAGTAACAGCCTACANGGTTATACCCCAGGAAGTTTAGATTACCCTC
ATACCATTGNATCATCCTGCTATAAAAAAGTACTCTAAACTATTTCTTTTGCTATTAATG
AAAAAGATTAAATATTTGGTCACCTGGAATATTGCTATGCCAGACCTTCGCAACTGCAAG
TATTTAATCCGAGATATGTCNACCCCTCCCAACTGACCCCGGTGAGCCCCCTGGGGCAAA
AGGAAGCCCTTGGCCGGTAAAGGAAATCCGGACTGATATAGCTTGGTTGGGGTGCCACCC
GGCCCCGGCCANTGT
Restriction Sites NotI-NotI     
ACCN NM_031991
Insert Size 3260 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_031991.2, NP_114368.1
RefSeq Size 3241 bp
RefSeq ORF 1596 bp
Locus ID 5725
Cytogenetics 19p13.3
Domains RRM
Protein Families Druggable Genome
Gene Summary 'This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]'
Transcript Variant: This variant (3) lacks 78 nt in the coding region compared to variant 1. Thus isoform c is 26 aa shorter than isoform a but it maintains the same reading frame.

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.