TXNDC (TMX1) (NM_030755) Human Untagged Clone

CAT#: SC109735

TMX1 (untagged)-Human thioredoxin-related transmembrane protein 1 (TMX1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TMX1
• Synonyms: PDIA11; TMX; TXNDC; TXNDC1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC109735 sequence for NM_030755 edited (data generated by NextGen Sequencing)
  ATGGCGCCCTCCGGGAGTCTTGCAGTTCCCCTGGCAGTCCTGGTGCTGTTGCTTTGGGGT
  GCTCCCTGGACGCACGGGCGGCGGAGCAACGTTCGCGTCATCACGGACGAGAACTGGAGA
  GAACTGCTGGAAGGAGACTGGATGATAGAATTTTATGCCCCGTGGTGCCCTGCTTGTCAA
  AATCTTCAACCGGAATGGGAAAGTTTTGCTGAATGGGGAGAAGATCTTGAGGTTAATATT
  GCGAAAGTAGATGTCACAGAGCAGCCAGGACTGAGTGGACGGTTTATCATAACTGCTCTT
  CCTACTATTTATCATTGTAAAGATGGTGAATTTAGGCGCTATCAGGGTCCAAGGACTAAG
  AAGGACTTCATAAACTTTATAAGTGATAAAGAGTGGAAGAGTATTGAGCCCGTTTCATCA
  TGGTTTGGTCCAGGTTCTGTTCTGATGAGTAGTATGTCAGCACTCTTTCAGCTATCTATG
  TGGATCAGGACGTGCCATAACTACTTTATTGAAGACCTTGGATTGCCAGTGTGGGGATCA
  TATACTGTTTTTGCTTTAGCAACTCTGTTTTCCGGACTGTTATTAGGACTCTGTATGATA
  TTTGTGGCAGATTGCCTTTGTCCTTCAAAAAGGCGCAGACCACAGCCATACCCATACCCT
  TCAAAAAAATTATTATCAGAATCTGCACAACCTTTGAAAAAAGTGGAGGAGGAACAAGAG
  GCGGATGAAGAAGATGTTTCAGAAGAAGAAGCTGAAAGTAAAGAAGGAACAAACAAAGAC
  TTTCCACAGAATGCCATAAGACAACGCTCTCTGGGTCCATCATTGGCCACAGATAAATCC
  TAG
  
  Clone variation with respect to NM_030755.4
  492 t=>g;648 g=>a
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_030755 unedited
  CCAGTCAGCAATTGTATACGACTCATATAGGCGGCCGCTGAATTCGCACGAGGCAGCCCG
  CGAGGGCGGAAGTGGGAGCTGCGACCGCGCTCCCTGTGAGGTGGGCAAGCGGCGAAATGG
  CGCCCTCCGGGAGTCTTGCAGTTCCCCTGGCAGTCCTGGTGCTGTTGCTTTGGGGTGCTC
  CCTGGACGCACGGGCGGCGGAGCAACGTTCGCGTCATCACGGACGAGAACTGGAGAGAAC
  TGCTGGAAGGAGACTGGATGATAGAATTTTATGCCCCGTGGTGCCCTGCTTGTCAAAATC
  TTCAACCGGAATGGGAAAGTTTTGCTGAATGGGGAGAAGATCTTGAGGTTAATATTGCGA
  AAGTAGATGTCACAGAGCAGCCAGGACTGAGTGGACGGTTTATCATAACTGCTCTTCCTA
  CTATTTATCATTGTAAAGATGGTGAATTTAGGCGCTATCAGGGTCCAAGGACTAAGAAGG
  ACTTCATAAACTTTATAAGTGATAAAGAGTGGAAGAGTATTGAGCCCGTTTCATCATGGT
  TTGGTCCAGGTTCTGTTCTGATGAGTAGTATGTCAGCACTCTTTCAGCTATCTATGTGGA
  TCAGGACGTGCCATAACTACTTTATTGAAGACCTTGGATTGCCAGTGTGGGGATCATATA
  CTGTTTTTGCTTTAGCAACTCTGTTTTCCGGACTGTTATTAGGACTCTGTATGATATTTG
  TGGCAGATTGCCTTTGTCCTTCAAAAAGGCGCAGACCACAGCCATACCCATACTCTTTAG
  AAACATTATTATCAGAATCTGCACACCTTTTGAAAAAAGTGGAGAGGAACAAGAGGCTGA
  TGAAGAAGATGTTTCACACGAGCAGCTGAAAGTAAAGAGGAACAAACAAGACTTTCCCAA
  ATGCCATAGA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_030755 unedited
  CCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAAAAGGGGTAAAAAGGGTTTTTTTGGGCT
  TAAGAATTTTTTTTAAGGGCTCACAAGTTCCCCCTCCAAACTTTTTAAGGGGCCAATTTT
  TTAAATTTTAAAGGAAAGGGCTTTAAAAAAAACTTTTTTTTTCCCAACCCGGAAATTTAA
  GGGGTTCCCCCCCCACCAAACCCTAAAAAAAAGGGGCCCTTTCCAAAATTGCCTCCCCCC
  AAAGGGGCAAGGGATTCATTGGATTTAAAAATTCCCCCCTTTTTTTAAGGGGAAAACTTT
  TTTTTTTACCTTTTTAAGGGGAAAAAACCCCCCAAAAGGGCCCCCCCCCCCGCCTTTTCC
  CCGGGAAACCCCCCCCCATTTTCCCCCCCCGGAAAAAACCCCGGGTAATTTGAAGTTTGT
  CTTTTAAAAAATAAAAAAATGTTTTTTTTTTAAAACATCAACCCTTCCCACCTGGAAAAA
  CAATTAAAAACCTTTTGTTTTTGAGGGCCAAAATACCTTTAAAACATTTACCAAAAAAAG
  CTTTTTCCTGAAAAAAAAGCAAACTTTTATTTTAACCCTTTTTGAATTTTCAAAATGGAA
  AACACCAAGGGTTTTTCCCCTTAAACAAAAATCTCGAATGGCTCCCCTTCCCCCCCCAAA
  AGAAAAAAACAAAAAAACCACTTCTCAGTTGAAGCTCCCCCAGAAAGGTTGAAAATTTCA
  GAAAAAGGGCCCCAAATTTTAAATTACCCCACAAATTGTCCAATTTGGAGGGAGTCCTCC
  ACAAACCCCTTANTTTGAAAACACACAAAAAAACCTGGCTACTTAAAACATAAAAAATGT
  TCCCAAAAATTTTCTCTCCCTTTGAAAATAAAAAGGCCCCCTTTTGGTTAGAAAACACCG
  GAAAATC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_030755
• ORF Size: 843 bp
• Insert Size: 2550
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_030755.3, NP_110382.2
• RefSeq Size: 2473
• RefSeq ORF: 843
• Locus ID: 81542
• Domains: thiored
• Protein Families: Druggable Genome, Transcription Factors, Transmembrane
• Gene Summary: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and one transmembrane domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The mature membrane-bound protein can both oxidize and reduce disulfide bonds and acts selectively on membrane-associated polypeptides. [provided by RefSeq, Jan 2017]