CCL14 (NM_004166) Human Untagged Clone

CAT#: SC109751

CCL14 (untagged)-Human chemokine (C-C motif) ligand 14 (CCL14), transcript variant 1


  "NM_004166" in other vectors (4)

Reconstitution Protocol

USD 420.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol CCL14
Synonyms CC-1; CC-3; CKb1; FLJ16015; HCC-1; HCC-3; MCIF; NCC-2; NCC2; SCYA14; SCYL2; SY14
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC109751 sequence for NM_004166 edited (data generated by NextGen Sequencing)
ATGAAGATCTCCGTGGCTGCCATTCCCTTCTTCCTCCTCATCACCATCGCCCTAGGGACC
AAGACTGAATCCTCCTCACGGGGACCTTACCACCCCTCAGAGTGCTGCTTCACCTACACT
ACCTACAAGATCCCGCGTCAGCGGATTATGGATTACTATGAGACCAACAGCCAGTGCTCC
AAGCCCGGAATTGTCTTCATCACCAAAAGGGGCCATTCCGTCTGTACCAACCCCAGTGAC
AAGTGGGTCCAGGACTATATCAAGGACATGAAGGAGAACTGA

Clone variation with respect to NM_004166.4
>OriGene 5' read for NM_004166 unedited
CAATAGGTCATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGCCGCAGGAGCCT
CTGAAGCTCCCACCAGGCCAGCTCTCCTCCCACACACTTCCCACAGCATGAAGATCTCCG
TGGCTGCCATTCCCTTCTTCCTCCTCATCACCATCGCCCTAGGGACCAAGACTGAATCCT
CCTCACGGGGACCTTACCACCCCTCAGAGTGCTGCTTCACCTACACTACCTACAAGATCC
CGCGTCAGCGGATTATGGATTACTATGAGACCAACAGCCAGTGCTCCAAGCCCGGAATTG
TCTTCATCACCAAAAGGGGCCATTCCGTCTGTACCAACCCCAGTGACAAGTGGGTCCAGG
ACTATATCAAGGACATGAACGAGAACTGAGTGACCCAGAAGGGGTGGCGAAGGCACAGCT
CAGAGACATAAAGAGAAGATGCCAAGGCCCCCTCCTNCACCCACCGCTAACTCTCAGCCC
CAGTCACCCTCTTGGAGCTTCCCTGCTTTGAATTAAAGACCACCTCATGCTCTTAAAAAA
AAAAAAAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCGCCGGACATAGCTGTTT
CCTGAACAGATCCCGGGTGGCATCCCTGTGACCCCTCCCCAGGCCTTTTCTGGCCCTGGG
AGCTGCCCCTCCAGTGCCAACCACCTTGGTCCTAAAAAAATAAATCGCTCATTTCTGCTG
AATAAGAGTCCCTCTACAACATACGGGGGGCAGGGGGCGCATGGAACAAGGGCACGTTGG
AAGACAACCTGAAGGCCGCGGGTCCAATGGAACCAGCCGGATGCAGGGGCCCAACTGGCT
ACTGAATCTCGGCCCCGGGTTAAACCAATTCTGCCCCACCCTCCGAGTGTCGGGATCCAG
CCTGCCTGCCCCCCCATTAATTTTGTTCTTTGTAAAAACGGGTTACCTTATGC
>OriGene 3' read for NM_004166 unedited
NNNNNNAAAANNTTACTTGNACCGCGCCGCAATCTAGATCGAGTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTAAAAGCATGAGTGGTCTTTAATTCAAAGCAGGAAGCTCCAAAAGGTGA
CTGGGGCTGAAAGTTACCGGTGGGTGGAGGAGGGGGCCTTGGCATCTTCTCTTTATGTCT
CTGAGCTGTGCCTTCGCCACCCCTTCTGGGTCACTCAGTTCTCCTTCATGTCCTTGATAT
AGTCCTGGACCCACTTGTCACTGGGGTTGGTACAGACGGAATGGCCCCTTTTGGTGATGA
AGACAATTCCGGGCTTGGAGCACTGGCTGTTGGTCTCATAGTAATCCATAATCCGCTGAC
GCGGGATCTTGTAGGTAGTGTAGGTGAAGCAGCACTCTGAGGGGTGGTAAGGTCCCCGTG
AGGAGGATTCAGTCTTGGTCCCTAGGGCGATGGTGATGAGGAGGAAGAAGGGAATGGCAG
CCACGGAGATCTTCATGCTGTGGGAAGCTGTTGTGGGAGGAGAGCTGGCCTGGTGGGAGC
TTCAGAGGCTCCTGCGGCTCGTGCCGAATTCGCGGCCGCCCTATAGTGAGTCGTATTACA
AAATTCTGACGGTTCACTAAACGAGCTCTGCTTATATAGACCTNCCACCGTACACGCCTA
CCGNCCATTTGCGTCAACGGGGGCGGNGTTATTACGACATTTTGGAAAGTCCCGTTGATT
TTGGTGCCAAAAACAACTCCCATTGACGTCAATGGGGGTGGAGACTTGNAAATCCCCGTG
AGTCAAACCGCTATCCACGCCCATTNGNTGTACTGCCCAAACCGCATCACCATGGGTTAT
AGCGATGACTAATACCTTANATGTACTGCCCCAAGTANGAAAGTCCCCGTAAGGTCATGT
ACTGGGGCATAATGCCAGGCGGG
Restriction Sites NotI-NotI     
ACCN NM_004166
Insert Size 550 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_004166.3, NP_004157.1
RefSeq Size 1344 bp
RefSeq ORF 282 bp
Locus ID 6358
Cytogenetics 17q12
Domains IL8
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction
Gene Summary 'This gene, chemokine (C-C motif) ligand 14, is one of several CC cytokine genes clustered on 17q11.2. The CC cytokines are secreted proteins characterized by two adjacent cysteines. The cytokine encoded by this gene induces changes in intracellular calcium concentration and enzyme release in monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Read-through transcripts are also expressed that include exons from the upstream cytokine gene, chemokine (C-C motif) ligand 15, and are represented as GeneID: 348249. [provided by RefSeq, Dec 2009]'
Transcript Variant: This variant (1) is a bicistronic transcript that includes CCL14 and CCL15. Variant 1 lacks an in-frame exon in the CCL14 coding region, compared to variant 2. Variants 1 and 3 encode isoform 1, which is shorter than isoform 2.

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