TAP2 (NM_000544) Human Untagged Clone

CAT#: SC109816

TAP2 (untagged)-Human transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) (TAP2), transcript variant 1


  "NM_000544" in other vectors (4)

Reconstitution Protocol

USD 1,430.00

5 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol TAP2
Synonyms ABC18; ABCB3; APT2; D6S217E; PSF-2; PSF2; RING11
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_000544, the custom clone sequence may differ by one or more nucleotides


ATGCGGCTCCCTGACCTGAGACCCTGGACCTCCCTGCTGCTGGTGGACGCGGCTTTACTGTGGCTGCTTC
AGGGCCCTCTGGGGACTTTGCTTCCTCAAGGGCTGCCAGGACTATGGCTGGAGGGGACCCTGCGGCTGGG
AGGGCTGTGGGGGCTGCTAAAGCTAAGAGGGCTGCTGGGATTTGTGGGGACACTGCTGCTCCCGCTCTGT
CTGGCCACCCCCCTGACTGTCTCCCTGAGAGCCCTGGTCGCGGGGGCCTCACGTGCTCCCCCAGCCAGAG
TCGCTTCAGCCCCTTGGAGCTGGCTGCTGGTGGGGTACGGGGCTGCGGGGCTCAGCTGGTCACTGTGGGC
TGTTCTGAGCCCTCCTGGAGCCCAGGAGAAGGAGCAGGACCAGGTGAACAACAAAGTCTTGATGTGGAGG
CTGCTGAAGCTCTCCAGGCCGGACCTGCCTCTCCTCGTTGCCGCCTTCTTCTTCCTTGTCCTTGCTGTTT
TGGGTGAGACATTAATCCCTCACTATTCTGGTCGTGTGATTGACATCCTGGGAGGTGATTTTGACCCCCA
TGCCTTTGCCAGTGCCATCTTCTTCATGTGCCTCTTCTCCTTTGGCAGCTCACTGTCTGCAGGCTGCCGA
GGAGGCTGCTTCACCTACACCATGTCTCGAATCAACTTGCGGATCCGGGAGCAGCTTTTCTCCTCCCTGC
TGCGCCAGGACCTCGGTTTCTTCCAGGAGACTAAGACAGGGGAGCTGAACTCACGGCTGAGCTCGGATAC
CACCCTGATGAGTAACTGGCTTCCTTTAAATGCCAATGTGCTCTTGCGAAGCCTGGTGAAAGTGGTGGGG
CTGTATGGCTTCATGCTCAGCATATCGCCTCGACTCACCCTCCTTTCTCTGCTGCACATGCCCTTCACAA
TAGCAGCGGAGAAGGTGTACAACACCCGCCATCAGGAAGTGCTTCGGGAGATCCAGGATGCAGTGGCCAG
GGCGGGGCAGGTGGTGCGGGAAGCCGTTGGAGGGCTGCAGACCGTTCGCAGTTTTGGGGCCGAGGAGCAT
GAAGTCTGTCGCTATAAAGAGGCCCTTGAACAATGTCGGCAGCTGTATTGGCGGAGAGACCTGGAACGCG
CCTTGTACCTGCTCGTAAGGAGGGTGCTGCACTTGGGGGTGCAGATGCTGATGCTGAGCTGTGGGCTGCA
GCAGATGCAGGATGGGGAGCTCACCCAGGGCAGCCTGCTTTCCTTTATGATCTACCAGGAGAGCGTGGGG
AGCTATGTGCAGACCCTGGTATACATATATGGGGATATGCTCAGCAACGTGGGAGCTGCAGAGAAGGTTT
TCTCCTACATGGACCGACAGCCAAATCTGCCTTCACCTGGCACGCTTGCCCCCACCACTCTGCAGGGGGT
TGTGAAATTCCAAGACGTCTCCTTTGCATATCCCAATCGCCCTGACAGGCCTGTGCTCAAGGGGCTGACG
TTTACCCTACGTCCTGGTGAGGTGACGGCGCTGGTGGGACCCAATGGGTCTGGGAAGAGCACAGTGGCTG
CCCTGCTGCAGAATCTGTACCAGCCCACAGGGGGACAGGTGCTGCTGGATGAAAAGCCCATCTCACAGTA
TGAACACTGCTACCTGCACAGCCAGGTGGTTTCAGTTGGGCAGGAGCCTGTGCTGTTCTCCGGTTCTGTG
AGGAACAACATTGCTTATGGGCTGCAGAGCTGCGAAGATGATAAGGTGATGGCGGCTGCCCAGGCTGCCC
ACGCAGATGACTTCATCCAGGAAATGGAGCATGGAATATACACAGATGTAGGGGAGAAGGGAAGCCAGCT
GGCTGCGGGACAGAAACAACGTCTGGCCATTGCCCGGGCCCTTGTACGAGACCCGCGGGTCCTCATCCTG
GATGAGGCTACTAGTGCCCTAGATGTGCAGTGCGAGCAGGCCCTGCAGGACTGGAATTCCCGTGGGGATC
GCACAGTGCTGGTGATTGCTCACAGGCTGCAGGCAGTTCAGCGCGCCCACCAGATCCTGGTGCTCCAGGA
GGGCAAGCTGCAGAAGCTTGCCCAGCTCCAGGAGGGACAGGACCTCTATTCCCGCCTGGTTCAGCAGCGG
CTGATGGACTGA


>OriGene 5' read for NM_000544 unedited
CACAATTTGTATACGACTCACTATAGGCGGCCCGCGAATTCGCACGAGGCGGTAGCGAGG
TTGGGAGAGACGGAGCGGACCTCAGCGCTGAAGCAGAAGCCCCCGGAGCTGCGGTCTCCC
CGCCGCGGCTGAGCCATGCGGCTCCCTGACCTGAGACCCTGGACCTCCCTGCTGCTGGTG
GACGCGGCTTTACTGTGGCTGCTTCAGGGCCCTCTGGGGACTTTGCTTCCTCAAGGGCTG
CCAGGACTATGGCTGGAGGGGACCCTGCGGCTGGGAGGGCTGTGGGGGCTGCTAAAGCTA
AGAGGGCTGCTGGGATTTGTGGGGACACTGCTGCTCCCGCTCTGTCTGGCCACCCCCCTG
ACTGTCTCCCTGAGAGCCCTGGTCGCGGGGGCCTCACGTGCTCCCCCAGCCAGAGTCGCT
TCAGCCCCTTGGAGCTGGCTGCTGGTGGGGTACGGGGCTGCGGGGCTCAGCTGGTCACTG
TGGGCTGTTCTGAGCCCTCCTGGAGCCCAGGAGAAGGAGCAGGACCAGGTGAACAACAAA
GTCTTGATGTGGAGGCTGCTGAAGCTCTCCAGGCCGGACCTGCCTCTCCTCGTTGCCGCC
TTCTTCTTCCTTGTCCTTGCTGTTTTGGGTGAGACATTAATCCCTCACTATTCTGGTCGT
GTGATTGACATCCTGNGAGGTGATTTTGACCCCCATGCCTTTGCCAGTGCCATCTTCTTC
ATGTGCCCTCTCTCCTTTGGCAGCTCACTGTCTGCANGCTGCCCGAGAGGCTGCTTCACC
TACACCATGTCTCGAATCAACTTGCNGATCCGGGAGCAGCTTTTCTCCTCCCTGCTGCGC
CCAGACCCCTCGGTTCTTCCCAGNAGACTAAGACAAGGGGAGCTGAACTCACGCCTGACC
TCCGATACCAACCTGATGAAGTAACTGGCTTCCTTTA
>OriGene 3' read for NM_000544 unedited
ACCGCGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTATTTTAAAATATATGTA
TTATGCCACAAAATACTCCTCATCACCAGGCAAAGCTCTAGTCACCAGGGAATTAAGTTT
CCTGGACACAGACAGCCCCCACCCCACCCCACCCCACCTTTCCACCCCACCAAAAGCACA
CAGTGTCCAAATCTCCATCATGCCTGCAACTCAGGAACAGCTATCTGGCCGCACAGCTCT
AGGGAAACTCAAAGCAGGAACAGCTCTGGGTCCTGGAGACGCCCCTGAGAAGAGGGCCCA
GTATCCCTGGGGCCTCAGTCCATCAGCCGCTGCTGCACCAGGCGGGAATAAAGGTCCTGT
CCCTCCTAGAGCTGGGCAAGCTTTCTGCAGCTTGCCCTCCTGGAACACCCAGGATCTGGT
GGGCGCGCTGAACTGTCTGCAGCCTGTGAGCAATCACCACCACTGTGCGATCCCCACGGG
AATTCCATTCCTGCAGGGCCTGCTTTCACTTGCCATTTAGGCACTAGTTCCCCTCTCTCA
CTATGATGACCCTTCGGTTTCTCCATGGCCCGCGCCTTGTCCATACTTTGTTTTTGTCCC
GGCAATACATTGGCTCCCCTTCTCCCGACCTCTGGGGTATTCCCATGCCCCCATTCCCGC
ATGAAAAATCGGCGTGGACATCTGGCCAGCGCCTCACCTTTTATTCCTGTAATCTTCCTA
CCCATAACATCGTTTTTTCTACAATAACTCGTTATAATATATGTTTTTGCCAACTTAAAC
CCTCGGTTCTGCGCTTCCACGCTATTCCCGTNCATGGCTCTTGCCCCTCTCCCCTCGTCC
TCTTTGTCCTCTCATCTCCTCCCACAGCTACCCTTTGTTTTCCT
Restriction Sites NotI-NotI     
ACCN NM_000544
Insert Size 2380 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_000544.3, NP_000535.3
RefSeq Size 5679 bp
RefSeq ORF 2112 bp
Locus ID 6891
Cytogenetics 6p21.32
Domains ABC_membrane, ABC_tran, AAA
Protein Families Druggable Genome, Transmembrane
Protein Pathways ABC transporters, Antigen processing and presentation, Primary immunodeficiency
Gene Summary 'The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Feb 2014]'
Transcript Variant: This variant (1, B allele) represents the longer transcript and encodes the longest isoform (1). An allele (variant 1, A allele) exists in which a single nt change creates an internal stop codon, leading to a protein that is 17 aa shorter at the C-terminus.

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.