UNG (NM_003362) Human Untagged Clone

CAT#: SC109874

UNG (untagged)-Human uracil-DNA glycosylase (UNG), nuclear gene encoding mitochondrial protein, transcript variant 1


  "NM_003362" in other vectors (4)

Reconstitution Protocol

USD 660.00

In Stock*

Size
    • 10 ug

Product Images

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol UNG
Synonyms DGU; HIGM4; HIGM5; UDG; UNG1; UNG2; UNG15
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_003362, the custom clone sequence may differ by one or more nucleotides


ATGGGCGTCTTCTGCCTTGGGCCGTGGGGGTTGGGCCGGAAGCTGCGGACGCCTGGGAAGGGGCCGCTGC
AGCTCTTGAGCCGCCTCTGCGGGGACCACTTGCAGGCCATCCCAGCCAAGAAGGCCCCGGCTGGGCAGGA
GGAGCCTGGGACGCCGCCCTCCTCGCCGCTGAGTGCCGAGCAGTTGGACCGGATCCAGAGGAACAAGGCC
GCGGCCCTGCTCAGACTCGCGGCCCGCAACGTGCCCGTGGGCTTTGGAGAGAGCTGGAAGAAGCACCTCA
GCGGGGAGTTCGGGAAACCGTATTTTATCAAGCTAATGGGATTTGTTGCAGAAGAAAGAAAGCATTACAC
TGTTTATCCACCCCCACACCAAGTCTTCACCTGGACCCAGATGTGTGACATAAAAGATGTGAAGGTTGTC
ATCCTGGGACAGGATCCATATCATGGACCTAATCAAGCTCACGGGCTCTGCTTTAGTGTTCAAAGGCCTG
TTCCGCCTCCGCCCAGTTTGGAGAACATTTATAAAGAGTTGTCTACAGACATAGAGGATTTTGTTCATCC
TGGCCATGGAGATTTATCTGGGTGGGCCAAGCAAGGTGTTCTCCTTCTCAACGCTGTCCTCACGGTTCGT
GCCCATCAAGCCAACTCTCATAAGGAGCGAGGCTGGGAGCAGTTCACTGATGCAGTTGTGTCCTGGCTAA
ATCAGAACTCGAATGGCCTTGTTTTCTTGCTCTGGGGCTCTTATGCTCAGAAGAAGGGCAGTGCCATTGA
TAGGAAGCGGCACCATGTACTACAGACGGCTCATCCCTCCCCTTTGTCAGTGTATAGAGGGTTCTTTGGA
TGTAGACACTTTTCAAAGACCAATGAGCTGCTGCAGAAGTCTGGCAAGAAGCCCATTGACTGGAAGGAGC
TGTGA


>OriGene 5' read for NM_003362 unedited
GGGTCAAATTTGTATACGACTCCTATAGGCGGCCGCGNAATTCGCACGAGGGTCACCGCG
ACGCTCCTCGGGNAAGCCATAGGGCGCCTCCCAGCCCGTCTCCCCGCTCCAGTTTAGAAC
CTAATTCCCAATTCCCGGAAGCTGCGGACGCCTGGGAAGGGGCCGCTGCAGCTCTTGAGC
CGCCTCTGCGGGGACCACTTGCAGGCCATCCCAGCCAAGAAGGCCCCGGCTGGGCAGGAG
GAGCCTGGGACGCCGCCCTCCTCGCCGCTGAGTGCCGAGCAGTTGGACCGGATCCAGAGG
AACAAGGCCGCGGCCCTGCTCAGACTCGCGGCCCGCAACGTGCCCGTAGGCTTTGGAGAG
AGCTGGAAGAAGCACCTCAGCGGGGAGTTCGAGAAACCGTATTTTATCAAGCTAATGGGA
TTTGTTGCAGAAGAAAGAAAGCATTACACTGTTTATCCACCCCCACACCAAGTCTTCACC
TGGACCCAGATGTGTGACATAAAAGATGTGAAGGTTGTCATCCTGGGACAGGATCCATAT
CATGGACCTAATCAAGCTCACGGGCTCTGCTTTAGTGTTCAAAGGCCTGTTCCGCCTCCG
CCCAGTTTGGAGAACATTTATAAAGAGTTGTCTACAGACATAGAGGATTTTGTTCATCCT
GGCCATGGAGATTTATCTGGGTGGGCCAAGCAAGGTGTTCTCCTTCTCAACGCTGTCCTC
ACGGTTCGTGCCCATCAAGCCAACTCTCATAAGGAGCGAGGCTGGGAGCAGTTCACTGAT
GCAGTTGTGTCCTGGCTAAATCAGAACTCGAATGGGCCTNNGTTTTCTGCTCTGGGGCTC
TTATGCTCAGAAGAAGGCAGTGCCATTGATAGGAAGCGGCACCATGTACTACAGACGGNT
CATCCCTCCTTNTN
>OriGene 3' read for NM_003362 unedited
NNNNTATCTCTGNAACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTA
ACTTTTAACAAACTTTTATTAACAAACCTCGCGTAGAGCCAACTCTAACCCGACTAACAG
CAAAAACAGCATTGCTAACAAGATCAAGGATGGAGGTGCAGACCCAATAAAGACCGTCTC
TTAAAAAAAGGACTGGGAAAAATATATATATATATATCTGCATGAGTACTTCTTAAAAAA
CTAAAACTTTCCAGTGTTGCAGGAAAAAATATCCCAAAGTGATTTCAGTCGGTTAAAAAA
AACAGTACTTGGCAGTCTGTGCTGCCTTAAAAACCCCAACTGGACATAACCCTAGGAGAA
AATCACCCCACCCCATAAAGACAAAATTCCCTTTTCTCCTCTTCCTTGTTCAAATTCCAC
TGCTTATTCCACCAACACCCAAGGAATAACAAGACCCAGCTTACTTCTCTCGGTCTCTTA
TCTGATAAAGCTCACAGCAATCTTAACCTCTACTACAATCAGGAAATTGAGCCCTAATTT
CTGGGCCAGATTCTGGAAAGTTGCAAAACATCCTTATGCTGCGAGGGGCCTGAGGACTCC
TTCAAAGATCAAGGGGGCAGTGGAACTGGCAGAGACTGGCATGCCTGCCCTGCCAGGCTG
AGACAAGGGGACCTTTCTAAGCAAAACACCCCCACATCTGTCACTGAAAGTCTAACCAGG
CAAAACCAAGGAGCAACAGGCGCCCAAACTAGGCTGTGCCTGAAAAGTGCACATCTCCCC
TGTTTCACCATAAAGGCGAGGGAAAAAAAAGAGCCAACTGAGTATTTGACCTCATTTGTC
CTCTGCATAATTTAAGCCGAAACCATGTTGCAGAAAAAGACATTGGTCCAAAGGCACCCC
TTTGTGGTNTGGGGGTGGAAACACTCGGCATTCN
Restriction Sites ECoRI-NOT     
ACCN NM_003362
Insert Size 1950 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_003362.2, NP_003353.1
RefSeq Size 2081 bp
RefSeq ORF 915 bp
Locus ID 7374
Cytogenetics 12q24.11
Domains UDG
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Base excision repair, Primary immunodeficiency
Gene Summary 'This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010]'
Transcript Variant: This variant (1) uses the downstream promoter and a full-length exon 1B. It encodes the UNG1 isoform, which includes a mitochondrial targeting sequence.

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