Kv beta 1 (KCNAB1) (NM_172159) Human Untagged Clone

CAT#: SC109907

KCNAB1 (untagged)-Human potassium voltage-gated channel, shaker-related subfamily, beta member 1 (KCNAB1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KCNAB1
• Synonyms: AKR6A3; hKvb3; hKvBeta3; KCNA1B; KV-BETA-1; Kvb1.3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC109907 sequence for NM_172159 edited (data generated by NextGen Sequencing)
  ATGCAAGTCTCCATAGCCTGCACAGAGCACAATTTGAAGAGTCGGAATGGTGAGGACCGA
  CTTCTGAGCAAGCAGAGCTCCACCGCCCCCAATGTGGTGAACGCAGCCCGGGCCAAATTC
  CGCACGGTCGCTATCATCGCGCGCAGCCTGGGGACGTTCACGCCTCAGCATCACATTTCT
  CTCAAAGAGTCCACCGCAAAGCAGACTGGCATGAAATATAGGAATCTTGGAAAATCAGGA
  CTCAGAGTTTCTTGCTTGGGTCTTGGAACATGGGTGACATTTGGAGGTCAAATTTCAGAT
  GAGGTTGCTGAACGGCTGATGACCATCGCCTATGAAAGTGGTGTTAACCTCTTTGATACT
  GCCGAAGTCTATGCTGCTGGAAAGGCTGAAGTGATTCTGGGGAGCATCATCAAGAAGAAA
  GGCTGGAGGAGGTCCAGTCTGGTCATAACAACCAAACTCTACTGGGGTGGAAAAGCTGAA
  ACAGAAAGAGGGCTGTCAAGAAAGCATATTATTGAAGGATTGAAGGGCTCCCTCCAGAGG
  CTGCAGCTCGAGTATGTGGATGTGGTCTTTGCAAATCGACCGGACAGTAACACTCCCATG
  GAAGAAATTGTCCGAGCCATGACACATGTGATAAACCAAGGCATGGCGATGTACTGGGGC
  ACCTCGAGATGGAGTGCTATGGAGATCATGGAAGCCTATTCTGTAGCAAGACAGTTCAAT
  ATGATCCCACCGGTCTGTGAACAAGCTGAGTACCATCTTTTCCAGAGAGAGAAAGTGGAG
  GTCCAGCTGCCAGAGCTCTACCACAAAATAGGTGTTGGCGCAATGACATGGTCTCCACTT
  GCCTGTGGAATCATCTCAGGAAAATACGGAAACGGGGTGCCTGAAAGTTCCAGGGCTTCA
  CTGAAGTGCTACCAGTGGTTGAAAGAAAGAATTGTAAGTGAAGAAGGGAGAAAACAGCAA
  AACAAGCTAAAAGACCTTTCCCCAATTGCGGAGCGTCTGGGATGCACACTACCTCAGCTA
  GCTGTTGCGTGGTGCCTGAGAAATGAAGGTGTGAGTTCTGTGCTCCTGGGATCATCCACT
  CCTGAACAACTCATTGAAAACCTTGGTGCCATTCAGGTTCTCCCAAAGATGACATCACAT
  GTGGTAAATGAGATTGATAACATACTGCGCAACAAGCCCTACAGCAAGAAGGACTATAGA
  TCATAA
  
  Clone variation with respect to NM_172159.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_172159 unedited
  GATTTTGTAATCCGACTTACTATAGGGCGGCCGCGAATTCGGCACGAGGGGAGCAAGGAG
  GGCTTAAAAGAAAAGCGGAAATCCCCGCAACTGCTCAACCTCTCGTGACTGCCTGTGTTC
  TGGGGTTCTGAGAGGGACCGTGCGCTGCCTGGGGAAGCAATGCAAGTCTCCATAGCCTGC
  ACAGAGCACAATTTGAAGAGTCGGAATGGTGAGGACCGACTTCTGAGCAAGCAGAGCTCC
  ACCGCCCCCAATGTGGTGAACGCAGCCCGGGCCAAATTCCGCACGGTCGCTATCATCGCG
  CGCAGCCTGGGGACGTTCACGCCTCAGCATCACATTTCTCTCAAAGAGTCCACCGCAAAG
  CAGACTGGCATGAAATATAGGAATCTTGGAAAATCAGGACTCAGAGTTTCTTGCTTGGGT
  CTTGGAACATGGGTGACATTTGGAGGTCAAATTTCAGATGAGGTTGCTGAACGGCTGATG
  ACCATCGCCTATGAAAGTGGTGTTAACCTCTTTGATACTGCCGAAGTCTATGCTGCTGGA
  AAGGCTGAAGTGATTCTGGGGAGCATCATCAAGAAGAAAGGCTGGAGGAGGTCCAGTCTG
  GTCATAACAACCAAACTCTACTGGGGTGGAAAAGCTGAAACAGACAGAGGGCTGTCAAGA
  AAGCATATTATTGAAGGATTGAAGGGCTCCCTTCCAGAGCTGCAGCTCGAGTATGTGGAT
  GTGGTCTGTGCAAATCGACCTGACAGTAACACTCCCATGGAAGAAATGTCCGAGCCATGA
  CACATGTGATAAACCTAAGCATGGCGATGTACTGAGGCACCCTCAGATGCAGTGCTATGG
  AGATCATGGCAGCCTATTCTGTAGCAGACAGCTCATATGATCCCACGGTCTGTGAACAGC
  TGAGTACATCTTTTCANAAGAGAAGAGGAGTCCAGCTGCCAGACTCTACACAACTAGTGT
  NGGCGCATGACTGTNCTCACTGCTGTGGACATCTCAGAAATCG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_172159 unedited
  TTGTTACATTATGNACGCGGCCGCATTCTANGATCGAGTTTTTTTTTTTTTTTTTTAAAA
  TTGAATGCACAAAATGCTTTTATTACTCTAAGCAAAATAAATCAATCAAATCACATTTCC
  CATTAGACAGCACCTCAGCTCCTCTATACATACAGCAGTTCGCTGGATTGAATACACAAT
  GAACAACTGAAAATGATCAATTTCCATCATTCTGATAACACGGGCAAAAAATTCAAACTC
  TCTGTTAGAATACAGGTACTAGTAATCAAAAAGAAAATTTCTTGATATCTCCCACTAGCA
  TTTTCAGATTTAGAATTTAACCATGAAGTACATATCTAGAACTAATGACAGAAAATCGCA
  TTTTAAAATAATATTACAGTTCTTCTGTAAACCTCAGAGTGATTTCTGTGTGGGGAACTT
  GCTGACCAGAAAATTAAATGAGAATTTTGTACATCCTCAGATAGCCAAATAGAGTTAAAG
  GGCCACTCCCACACCACCCCCTTCAAAAAAAAAAAAACATGTTTTCTCTCTTTTTACAGA
  TATTGACACAGTATAGTCTCACAATTTTTCTCAAGTGGGATATTAATGAGGGTAAGTAGC
  CAATAGTGGCAGGGCTAGATACACCTCAGATTTCGAGTGCAACAAGGGTAAGCCCCATTA
  ATCCATGCAAAGAACTTTCATGCATATAGTTTAGTGCATATAATATGATTATAGAACCAG
  AAGTTCTTTCTTTAACATTTTGCTTTTCACTAGGCAAGTTAATTTACCCAGCATATTCTG
  AATAGTGACATAGCATTTTTCACAAAGCCAGTGGTTGACTTTCATGTTAACAATGCCCTC
  AAAATACCAAACATTATATTATAAAATCCCAGTGCTAATTAAACATGAACATTTGCCTTC
  C
  
• Restriction Sites: NotI-NotI
• ACCN: NM_172159
• ORF Size: 1206 bp
• Insert Size: 3200
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_172159.2, NP_751891.1
• RefSeq Size: 4094
• RefSeq ORF: 1206
• Locus ID: 7881
• Protein Families: Druggable Genome, Ion Channels: Other
• Gene Summary: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes distinct isoforms which are encoded by alternatively spliced transcript variants of this gene. Some of these isoforms are beta subunits, which form heteromultimeric complexes with alpha subunits and modulate the activity of the pore-forming alpha subunits. [provided by RefSeq, Apr 2015]
  Transcript Variant: This variant (3) has an alternate 5' sequence including the 5' UTR and the 5' coding region, as compared to variant 1. It encodes isoform 3, also known as kvb1.3, which has a shorter and distinct N-terminus than isoform 1.