CDC14B (NM_033331) Human Untagged Clone

CAT#: SC109948

CDC14B (untagged)-Human CDC14 cell division cycle 14 homolog B (S. cerevisiae) (CDC14B), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CDC14B
• Synonyms: Cdc14B1; Cdc14B2; CDC14B3; hCDC14B
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_033331 edited
  GGCGGGAGCCTCGGCGGGCGCGCGGGCGCGCGGGGCCATGGTCGTGGCCCCCTGACGGGC
  CGCGGCCGCCTCCATGAAGCGGAAAAGCGAGCGGCGGTCGAGCTGGGCCGCCGCGCCCCC
  CTGCTCGCGGCGCTGCTCGTCGACCTCGCCGGGTGTGAAGAAGATCCGCAGCTCCACGCA
  GCAAGACCCGCGCCGCCGGGACCCCCAGGACGACGTGTACCTGGACATCACCGATCGCCT
  TTGTTTTGCCATTCTCTACAGCAGACCAAAGAGTGCATCAAATGTACATTATTTCAGCAT
  AGATAATGAACTTGAATATGAGAACTTCTACGCAGATTTTGGACCACTCAATCTGGCAAT
  GGTTTACAGATATTGTTGCAAGATCAATAAGAAATTAAAGTCCATTACAATGTTAAGGAA
  GAAAATTGTTCATTTTACTGGCTCTGATCAGAGAAAACAAGCAAATGCTGCCTTCCTTGT
  TGGATGCTACATGGTTATATATTTGGGGAGAACCCCAGAAGAAGCATATAGAATATTAAT
  CTTTGGAGAGACATCCTATATTCCTTTCAGAGATGCTGCCTATGGAAGTTGCAATTTCTA
  CATTACACTTCTTGACTGTTTTCATGCAGTAAAGAAGGCAATGCAGTATGGCTTCCTTAA
  TTTCAACTCATTTAACCTTGATGAATATGAACACTATGAAAAAGCAGAAAATGGAGATTT
  AAATTGGATAATACCAGACCGATTTATTGCCTTCTGTGGACCTCATTCAAGAGCCAGACT
  TGAAAGTGGTTACCACCAACATTCTCCTGAGACTTATATTCAATATTTTAAGAATCACAA
  TGTTACTACCATTATTCGTCTGAATAAAAGGATGTATGATGCCAAACGCTTTACGGATGC
  TGGCTTCGATCACCATGATCTTTTCTTTGCGGATGGCAGCACCCCTACTGATGCCATTGT
  CAAAGAATTCCTAGATATCTGTGAAAATGCTGAGGGTGCCATTGCAGTACATTGCAAAGC
  TGGCCTTGGTCGCACGGGCACTCTGATAGCCTGCTACATCATGAAGCATTACAGGATGAC
  AGCAGCCGAGACCATTGCGTGGGTCAGGATCTGCAGACCTGGCTCGGTGATTGGGCCTCA
  GCAGCAGTTTTTGGTGATGAAGCAAACCAACCTCTGGCTGGAAGGGGACTATTTTCGTCA
  GAAGTTAAAGGGGCAGGAGAATGGACAACACAGAGCAGCCTTCTCCAAACTTCTCTCTGG
  CGTTGATGACATTTCCATAAATGGGGTCGAGAATCAAGATCAGCAAGAACCCGAACCGTA
  CAGTGATGATGACGAAATCAATGGAGTGACACAAGGTGATAGACTTCGGGCCTTGAAAAG
  CAGAAGACAATCCAAAACAAACGCTATTCCTCTCACAGTAATTCTTCAATCCAGTGTTCA
  GAGCTGTAAAACATCTGAACCTAACATTTCTGGCAGTGCAGGCATTACTAAAAGAACCAC
  CAGATCTGCTTCAAGGAAAAGCAGTGTTAAAAGTCTCTCCATTTCAAGGACTAAAACAGT
  CTTGCGTTAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_033331
• ORF Size: 1497 bp
• Insert Size: 1600
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_033331.1, NP_201588.1
• RefSeq Size: 4624
• RefSeq ORF: 1497
• Locus ID: 8555
• Domains: Y_phosphatase, DSPc, PTPc_motif
• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: Cell cycle
• Gene Summary: The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) encodes the longest isoform (2). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.