Cytohesin 1 (CYTH1) (NM_004762) Human Untagged Clone

CAT#: SC110039

CYTH1 (untagged)-Human cytohesin 1 (CYTH1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CYTH1
• Synonyms: B2-1; CYTOHESIN-1; D17S811E; PSCD1; SEC7
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC110039 sequence for NM_004762 edited (data generated by NextGen Sequencing)
  ATGGAGGAGGACGACAGCTACGTTCCCAGTGACCTGACAGCAGAGGAGCGTCAAGAACTG
  GAGAACATCCGACGGAGAAAACAGGAGCTGCTGGCTGACATTCAGAGGCTGAAGGATGAG
  ATAGCAGAAGTAGCTAATGAAATTGAAAACCTGGGATCCACAGAGGAAAGGAAAAACATG
  CAGAGGAACAAACAGGTAGCCATGGGCAGGAAAAAATTTAATATGGACCCTAAAAAGGGG
  ATCCAGTTCTTAATAGAGAACGACCTCCTGAAGAACACTTGTGAAGACATTGCCCAGTTC
  TTATATAAAGGCGAAGGGCTCAACAAGACAGCCATCGGCGACTACCTAGGGGAGAGAGAT
  GAGTTTAATATCCAGGTTCTTCATGCATTTGTGGAGCTGCATGAGTTCACTGATCTTAAT
  CTCGTCCAGGCACTACGGCAGTTCCTGTGGAGCTTCCGGCTACCCGGAGAGGCCCAGAAG
  ATCGACCGGATGATGGAGGCGTTTGCCCAGCGATATTGTCAGTGCAATAATGGCGTGTTC
  CAGTCCACGGATACTTGTTACGTCCTCTCCTTTGCCATCATCATGTTGAACACCAGTCTG
  CACAACCCCAATGTCAAAGATAAGCCCACTGTGGAGAGGTTCATTGCCATGAACCGAGGC
  ATCAATGATGGGGGAGACCTGCCGGAGGAGCTCCTCCGGAATCTCTATGAGAGCATAAAA
  AATGAACCCTTTAAAATCCCAGAAGACGACGGGAATGACCTCACTCACACTTTCTTCAAT
  CCAGACCGAGAAGGCTGGCTATTGAAACTCGGAGGTGGCAGGGTAAAGACTTGGAAGAGA
  CGCTGGTTCATTCTGACTGACAACTGCCTTTACTACTTTGAGTATACCACGGATAAGGAG
  CCCCGTGGAATCATCCCTTTAGAGAATCTGAGTATCCGGGAAGTGGAGGACTCCAAAAAA
  CCAAACTGCTTTGAGCTTTATATCCCCGACAATAAAGACCAAGTTATCAAGGCCTGCAAG
  ACCGAGGCTGACGGGCGGGTGGTGGAGGGGAACCACACTGTTTACCGGATCTCAGCTCCG
  ACGCCCGAGGAGAAGGAGGAGTGGATTAAGTGCATTAAAGCAGCCATCAGCAGGGACCCT
  TTCTACGAAATGCTCGCAGCACGGAAAAAGAAGGTCTCCTCCACGAAGCGACACTGA
  
  Clone variation with respect to NM_004762.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004762 unedited
  GTCAAATTTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGGCGAGCGGGGG
  CGCGGGTGGCGCGGCGGGACGCGAGCGGCGAGCCGGAGCGCGGAGCCCGGCTCCCGCACC
  ATGGAGGAGGACGACAGCTACGTTCCCAGTGACCTGACAGCAGAGGAGCGTCAAGAACTG
  GAGAACATCCGACGGAGAAAACAGGAGCTGCTGGCTGACATTCAGAGGCTGAAGGATGAG
  ATAGCAGAAGTAGCTAATGAAATTGAAAACCTGGGATCCACAGAGGAAAGGAAAAACATG
  CAGAGGAACAAACAGGTAGCCATGGGCAGGAAAAAATTTAATATGGACCCTAAAAAGGGG
  ATCCAGTTCTTAATAGAGAACGACCTCCTGAAGAACACTTGTGAAGACATTGCCCAGTTC
  TTATATAAAGGCGAAGGGCTCAACAAGACAGCCATCGGCGACTACCTAGGGGAGAGAGAT
  GAGTTTAATATCCAGGTTCTTCATGCATTTGTGGAGCTGCATGAGTTCACTGATCTTAAT
  CTCGTCCAGGCACTACGGCAGTTCCTGTGGAGCTTCCGGCTACCCGGAGAGGCCCAGAAG
  ATCGACCGGATGATGGAGGCGTTTGCCCAGCGATATTGTCAGTGCAATAATGGCGTGTTC
  CAGTCCACGGATACTTGTTACGTCCTCTCCTTTGCCATCATCATGTTGAACACCAGTCTG
  CACAACCCCATGTCAAAGATAAGCCCACTGTGGAGAGGTTCATTGCCATGAACCGAGGCA
  TCAATGATGGGGGAGACCTGCCGGNAGAGCTCCTTCGGAATCTCTATGAGAGCATAAAAA
  TGAACCCTTTAAATCCCAGAGACGACGGGATGACCTCACCACACTTTCTTCATCCAGACG
  ANAAGCTGGCTATGAACT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004762 unedited
  GTTTTTTGCTGCAGTGCCTTGGCGCTAGTTTACAAGGGCAAAAACAAACAAACAAAAACA
  ATTAGAATAATTATTTCTTAAAAACCCTGTCAACAACTTTCAGTCATTTCTTTATATTTT
  TGTATTTTGACAAAACTTCTTTTAAACAAATACAAAATAATCTAAAAGGAGAAAAACTAT
  ACATAGATTATTTACACCTCTGATAAATAGACTAATACTGACCCAGGTGCCTCTCTGTCT
  AGGAAACACTTGAGAACCAGGCCAGGGCCCGGGCCAGCTGGACAGGCTCCAGCACCGGCC
  CAAACACGCCCAGACCTCGGCAGGCACCACCTGGTTCTCCCACCCAGAAAGTTCAGGTTT
  CCAGCCTGGACCCTCTTCTGTCACCCTCACAAGCTCTGGCACAAAAGTGCCTAAAGCCAT
  TCCCTCCAGGTAGGATCTACACAAAGTGGCGGGGAGGGAGGTGACAGACTGTCCCCCTCT
  ATTCCTCCCACCACTCCTCTGCAAAAGCTATTTCCAGAGATGCTCGCCAACCCTAAAGGA
  TCAGAGGAGCCGTGGCGACGCGGCCCTGTGAAAACCCGCAGCTCCTCCACCTGCCTCCTC
  AGGGCTGCGCCCTGCACCGCCCTGGTCCANGGTCCTGTGGAGGGGCGGGGCGAGACGGCC
  AGCCAGCCAGCCACCTGCTCTGCCTGCACTGGCATGCTTGGCCCTGCCGGAGTGGCAGGA
  GCTGCCCTGAGAGTCCCTGAAAGACGGNAAGAAAATGCGTGGTGTACGGCTCCTTTATAC
  TGAATTGAGAGGGCAGGGCCAGCTACCCAGGCCTGCAGGGGAAAAAGAATGCGAGAGGCA
  TCCGCCCCCCCCTTCTCCATGTCCCCCAGGACAATAAAGGCCCTTTCCCTTTAGGGGCCA
  CCCAAATGCCTCCAGAGTNCAGTTGGGGCGGTTCCGGCAAAAAGCCGAACCTTAGGGGAC
  GGGAAGCCTCTCTTTCTCTCAAAGGTTGAGCTGTGGAGAGTACACCCATAGAAGTTTTCG
  GC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004762
• ORF Size: 1197 bp
• Insert Size: 3520
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_004762.1, NP_004753.1
• RefSeq Size: 3311
• RefSeq ORF: 1197
• Locus ID: 9267
• Domains: Sec7, PH
• Gene Summary: The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. A pseudogene of this gene has been defined on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
  Transcript Variant: This variant (1) encodes the longest isoform (1).