ASIC3 (NM_020321) Human Untagged Clone

CAT#: SC110043

ASIC3 (untagged)-Human amiloride-sensitive cation channel 3 (ACCN3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ASIC3
• Synonyms: ACCN3; DRASIC; SLNAC1; TNaC1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC110043 sequence for NM_020321 edited (data generated by NextGen Sequencing)
  ATGAAGCCCACCTCAGGCCCAGAGGAGGCCCGGCGGCCAGCCTCGGACATCCGCGTGTTC
  GCCAGCAACTGCTCGATGCACGGGCTGGGCCACGTCTTCGGGCCAGGCAGCCTGAGCCTG
  CGCCGGGGGATGTGGGCAGCGGCCGTGGTCCTGTCAGTGGCCACCTTCCTCTACCAGGTG
  GCTGAGAGGGTGCGCTACTACAGGGAGTTCCACCACCAGACTGCCCTGGATGAGCGAGAA
  AGCCACCGGCTCATCTTCCCGGCTGTCACCCTGTGCAACATCAACCCACTGCGCCGCTCG
  CGCCTAACGCCCAACGACCTGCACTGGGCTGGGTCTGCGCTGCTGGGCCTGGATCCCGCA
  GAGCACGCCGCCTTCCTGCGCGCCCTGGGCCGGCCCCCTGCACCGCCCGGCTTCATGCCC
  AGTCCCACCTTTGACATGGCGCAACTCTATGCCCGTGCTGGGCACTCCCTGGATGACATG
  CTGCTGGACTGTCGCTTCCGTGGCCAACCTTGTGGGCCTGAGAACTTCACCACGATCTTC
  ACCCGGATGGGAAAGTGCTACACATTTAACTCTGGCGCTGATGGGGCAGAGCTGCTCACC
  ACTACTAGGGGTGGCATGGGCAATGGGCTGGACATCATGCTGGACGTGCAGCAGGAGGAA
  TATCTACCTGTGTGGAGGGACAATGAGGAGACCCCGTTTGAGGTGGGGATCCGAGTGCAG
  ATCCACAGCCAGGAGGAGCCGCCCATCATCGATCAGCTGGGCTTGGGGGTGTCCCCGGGC
  TACCAGACCTTTGTTTCTTGCCAGCAGCAGCAGCTGAGCTTCCTGCCACCGCCCTGGGGC
  GATTGCAGTTCAGCATCTCTGAACCCCAACTATGAGCCAGAGCCCTCTGATCCCCTAGGC
  TCCCCCAGCCCCAGCCCCAGCCCTCCCTATACCCTTATGGGGTGTCGCCTGGCCTGCGAA
  ACCCGCTACGTGGCTCGGAAGTGCGGCTGCCGAATGGTGTACATGCCAGGCGACGTGCCA
  GTGTGCAGCCCCCAGCAGTACAAGAACTGTGCCCACCCGGCCATAGATGCCATGCTTCGC
  AAGGACTCGTGCGCCTGCCCCAACCCGTGCGCCAGCACGCGCTACGCCAAGGAGCTCTCC
  ATGGTGCGGATCCCGAGCCGCGCCGCCGCGCGCTTCCTGGCCCGGAAGCTCAACCGCAGC
  GAGGCCTACATCGCGGAGAACGTGCTGGCCCTGGACATCTTCTTTGAGGCCCTCAACTAT
  GAGACCGTGGAGCAGAAGAAGGCCTATGAGATGTCAGAGCTGCTTGGTGACATTGGGGGC
  CAGATGGGGCTGTTCATCGGGGCCAGCCTGCTCACCATCCTCGAGATCCTAGACTACCTC
  TGTGAGGTGTTCCGAGACAAGGTCCTGGGATATTTCTGGAACCGACAGCACTCCCAAAGG
  CACTCCAGCACCAATCTGCTTCAGGAAGGGCTGGGCAGCCATCGAACCCAAGTTCCCCAC
  CTCAGCCTGGGCCCCAGCACTCTGCTCTGTTCCGAAGACCTCCCACCCCTCCCTGTGCCG
  TCACCAAGACTCTCTCCGCCTCCCACCGCACCTGCTACCTTGTCACACAGCTCTAGACCT
  GCTGTCTGTGTCCTCGGAGCCCCGCCCTGA
  
  Clone variation with respect to NM_020321.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020321 unedited
  NCGGTTAGATTTTGTATACGACTTACTATAGGCGGCCGCGAATTCGCACCAGCTGCCTTC
  CAACCTTGGCTGTCTCCCACCCTCTCTTCTCCTCTCCTTGCCTGGCCTCCTGAATCCTAT
  CTTAGCCTCCTTAGCCCCCTGACTGACTCTCTCTCGCTTCTTCCAAGCCTCTGTAGCTGG
  TTCCGCTCCTGGGTTCTGGCCATGAAGCCCACCTCAGGCCCAGAGGAGGCCCGGCGGCCA
  GCCTCGGACATCCGCGTGTTCGCCAGCAACTGCTCGATGCACGGGCTGGGCCACGTCTTC
  GGGCCAGGCAGCCTGAGCCTGCGCCGGGGGATGTGGGCAGCGGCCGTGGTCCTGTCAGTG
  GCCACCTTCCTCTACCAGGTGGCTGAGAGGGTGCGCTACTACAGGGAGTTCCACCACCAG
  ACTGCCCTGGATGAGCGAGAAAGCCACCGGCTCATCTTCCCGGCTGTCACCCTGTGCAAC
  ATCAACCCACTGCGCCGCTCGCGCCTAACGCCCAACGACCTGCACTGGGCTGGGTCTGCG
  CTGCTGGGCCTGGATCCCGCAGAGCACGCCGCCTTCCTGCGCGCCCTGGGCCGGCCCCCT
  GCACCGCCCGGCTTCATGCCCAGTCCCACCTTTGACATGGCGCAACTCTATGCCCGTGCT
  GGGCACTCCCTGGATGACATGCTGCTGGACTGTCGCTTCCGTGGCCAACCCTTGTGGGCC
  TGAGAACTTCACCACGATCTTCACCCGGATGGGAAAGTGCTACACATTTAACTCTGGCGC
  TGATGGGGCAGAGCTGCTCACCACTACTAGGGGTGGCATGGGGCAATGGGCTGAACATCA
  TGCTNGACGTGCAGCAGGAGGAATATCTACCTGTGTGGAGGGACAAATGAGAGACCCCGT
  TTGAGGTGGGGATCCGATTGCAGATCCCCANCCAGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_020321 unedited
  TTTTGCCGTACNTAGTACCGCGCCGCTTTCTANGATCNGTTTTTTTTTTTTTTTTTTTGC
  TGATGCATTAGGACTTTATTTGGGGTGAAGACGGAAAAGCTACGTGCAGGCTAGGCATGT
  CCAGGATGTCAGGGCGGGGCTCCGAGGACACAGACAGCAGGTCTAGAGCTGTGTGACAAG
  GTAGCAGGTGCGGTGGGAGGCGGAGAGAGTCTTGGTGACGGCACAGGGAGGGGTGGGAGG
  TCTTCGGAACAGAGCAGAGTGCTGGGGCCCAGGCTGAGGTGGGGAACTTGGGTTCGATGG
  CTGCCCAGCCCTTCCTGAAGCAGATTGGTGCTGGAGTGCCTTTGGGAGTGCTGTCGGTTC
  CAGAAATATCCCAGGACCTTGTCTCGGAACACCTCACAGAGGTAGTCTAGGATCTCGAGG
  ATGGTGAGCAGGCTGGCCCCGATGAACAGCCCCATCTGGCCCCCAATGTCACCAAGCAGC
  TCTGACATCTCATAGGCCTTCTTCTGCTCCACGGTCTCATAGTTGAGGGCCTCAAAGAAG
  ATGTCCAGGGCCAGCACGTTCTCCGCGATGTAAGCCTCGCTGCGGTTGAGCTTCCGGGCC
  AGGAAGCGCGCGGCGGCGCGGCTCGGGATCCGCACCATGGAGAGCTCCTTGGCGTAACGC
  GTGCTGGCGCACGGGTTGGGGCAGGCGCACGAGTCCTTGCGAAGCATGGCATCTATGGCC
  GGGTGGGCACAGTTCTTGTACTGCTGGGGGCTGCACACTGGCACGTCGCCTGGCATGTAC
  ACCATTCGGCAGCCGCACTTCCGAGCCACGTAACGGGTTTCGCAGGCCAGGCGACACCCC
  CTAAGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_020321
• ORF Size: 1650 bp
• Insert Size: 2250
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_020321.1, NP_064717.1
• RefSeq Size: 1766
• RefSeq ORF: 1650
• Locus ID: 9311
• Domains: ASC
• Protein Families: Druggable Genome, Ion Channels: Other
• Gene Summary: This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]
  Transcript Variant: This variant (2) represents the longest transcript and encodes the longest isoform (b).