TANK (NM_133484) Human Untagged Clone

CAT#: SC110107

TANK (untagged)-Human TRAF family member-associated NFKB activator (TANK), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TANK
• Synonyms: I-TRAF; ITRAF; TRAF2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_133484, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGATAAAAACATTGGCGAGCAACTCAATAAAGCGTATGAAGCCTTCCGGCAGGCATGCATGGATAGAG
  ATTCTGCAGTAAAAGAATTACAGCAAAAGACTGAGAACTATGAGCAGAGAATACGTGAACAACAGGAACA
  GCTGTCACTTCAACAGACTATTATTGACAAGCTAAAATCTCAGTTACTTCTTGTGAATTCCACTCAAGAT
  AACAATTATGGCTGTGTTCCTCTGCTTGAAGACAGTGAAACAAGAAAGAATAATTTGACTCTTGATCAGC
  CACAAGATAAAGTGATTTCAGGAATAGCAAGAGAAAAACTACCAAAGGTAGACATTGCTTCTGCAGAAAG
  CAGCATTTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_133484 unedited
  TCCCATTTTGTAATACGACTCACTATTAGGGCGGCCGCGATTCGGCACCAGGNACAGTTT
  AAGCAGCATTGTTAGAGCCTGTGGGAAAACACTTTACAACTGTGTAACTGTCTTCATCTT
  TACAGAGGAATAGTCTACAAAGGAAGACTTGTAACCTGGAGAAGAGACCTGTCATTTACT
  CCATCCTTTATAGTGATGCTACAGGACGAAGAGGAATGGATAAAAACATTGGCGAGCAAC
  TCAATAAAGCGTATGAAGCCTTCCGGCAGGCATGCATGGATAGAGATTCTGCAGTAAAAG
  AATTACAGCAAAAGACTGAGAACTATGAGCAGAGAATACGTGAACAACAGGAACAGCTGT
  CACTTCAACAGACTATTATTGACAAGCTAAAATCTCAGTTACTTCTTGTGAATTCCACTC
  AAGATAACAATTATGGCTGTGTTCCTCTGCTTGAAGACAGTGAAACAAGAAAGAATAATT
  TGACTCTTGATCAGCCACAAGATAAAGTGATTTCAGGAATAGCAAGAGAAAAACTACCAA
  AGGTAAGAAGACAAGAGGTTTCTTCTNCTAGAAAAGAACTTCAGAAGGAGTCTTGGCAGT
  CCTTTGCTCCATGAAAGGGGTAATATAGAGAAGACTTTCTGGGATCTGAAAGAAGATTTC
  ATAAAATATGCATGCTAGCANAAGCACAGAAAGACCACTTNAGCAAACTTTATATACCAG
  ACACTGCAACTGAAACACAGTGCTCTGTGCCTATACAGTGTACGGATNAAACAGATAAAC
  AAGAAAGCGCTGTTAAGCCTCAGCTAAAGATGATATAATAGAGGTGCACATTCACACATC
  TGTACACCAGAAGACTGTGCNAGATAAGGAGAACCTCCTTTGAATACTTTCTAAATCATG
  TCAGTTTCCACTATGGACATGACTCACTTTTTACTANCACTCAGAAGACCGCACCTTATT
  CTGCAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_133484
• ORF Size: 360 bp
• Insert Size: 2500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_133484.1, NP_597841.1
• RefSeq Size: 698
• RefSeq ORF: 360
• Locus ID: 10010
• Protein Families: Druggable Genome
• Protein Pathways: RIG-I-like receptor signaling pathway
• Gene Summary: The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
  Transcript Variant: This variant (2) lacks multiple exons from the 3' end and contains an alternate 3' segment compared to variant 1. The resulting isoform (b) has a shorter and distinct C-terminus, as compared to isoform (a).