SIVA (SIVA1) (NM_021709) Human Untagged Clone

CAT#: SC110171

SIVA1 (untagged)-Human SIVA1, apoptosis-inducing factor (SIVA1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SIVA1
• Synonyms: CD27BP; SIVA; Siva-1; Siva-2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_021709, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCCCAAGCGGAGCTGCCCCTTCGCGGACGTGGCCCCGCTACAGCTCAAGGTCCGCGTGAGCCAGAGGG
  AGTTGAGCCGCGGCGTGTGCGCCGAGCGCTACTCGCAGGAGGTCTTCGACCCATCTGGGGTAGCGTCCAT
  TGCCTGTTCCTCATGCGTGCGAGCCGTGGATGGGAAGGCGGTCTGCGGTCAGTGTGAGCGAGCCCTGTGC
  GGGCAGTGTGTGCGCACCTGCTGGGGCTGCGGCTCCGTGGCCTGTACCCTGTGTGGCCTCGTGGACTGCA
  GTGACATGTACGAGAAAGTGCTGTGCACCAGCTGTGCCATGTTCGAGACCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021709 unedited
  NTGTTCANATTTGTATACGACTCCTATAGGCGGCCGCGNAATTCGCACGAGGCCCCGCTA
  CAGCTCAAGGTCCGCGTGAGCCAGAGGGAGTTGAGCCGCGGCGTGTGCGCCGAGCGCTAC
  TCGCAGGAGGTCTTCGAGAAGACCAAGCGACTCCTGTTCCTCGGGGCCCAGGCCTACCTG
  GACCACGTGTGGGATGAAGGCTGTGCTGTCGTTCACCTGCCAGAGTCCCCAAAGCCTGGC
  CCTACAGGGGCCCCGAGGGCTGCACGTGGGCAGATGCTGATTGGACCAGACGGCCGCCTG
  ATCAGGAGCCTTGGGCAGGCCTCCGAAGCTGACCCATCTGGGGTAGCGTCCATTGCCTGT
  TCCTCATGCGTGCGAGCCGTGGATGGGAAGGCGGTCTGCGGTCAGTGTGAGCGAGCCCTG
  TGCGGGCAGTGTGTGCGCACCTGCTGGGGCTGCGGCTCCGTGGCCTGTACCCTGTGTGGC
  CTCGTGGAGTAAGTACTTCAGTCCCTGGAGCTGCTGAGATCCCATAGCCCCAGCAAGCCG
  TGATGGGGGACGGGTGGGTCACCCATGTGGGCCCAGAACACACACATGTGTGGCCCCTGA
  TGCAGTGCCATCTGGCATTGCCTAACGGGACATGGTGGCAATAGATGCTTGGCCCAACTT
  TAGTGGTTAGTAATCCTCTCTAAGGGAAAGCTGAACCTCACAGATGACCTGCTCTGTATC
  CGGCTCTAGTCCCTGTCTTCAGCCACTTCCTGTTCTATTTTNTGGAAACACCCCCACCTN
  CTNCTNCTNTGGTNCTTTGAGCCCCCCCTCCCCCCGTCCGAGGAGCCCCCTGGNTTGGTG
  ACACNAGTGCACACTGCAGCTTCACACAGTCATGCGTGCCGTTTGGTTGTAGACCCTCTC
  NNAGCAGAAGTGGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_021709 unedited
  GGCACGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGC
  AAATATAAAGAGGGTTATTCATTCTGTGCTTAGGATACAAAATAGAACATGTAAAAGGGA
  CCCCTTCCGTCGACCCCACAGTTTAATGGGAACACCGAGCGCTCGTCCAAGGAAAGGTGC
  CATGCACGGGGTGGCTCCCGGTGAAAGCAGCCGGCTTGAGCCAACCTCAAGTCTTGAACA
  TGGCACAGCTGGTGCACAAGACTTTTTTGTACATGTCACTGGAACTGCGACAGCGTCAGG
  GAGGGGAAAAAAAAACTGCTGTCAAGGGCTGAATTGTGTCCACCACCCCCCACCATTTAA
  ACGTCAAAGTCCTAACCCAGAACACCTCAGGACATGACCTTATTTGGAGACAGGATCACT
  GCGGGCATCATCAGTCTAAATGACGGCACTGACATGGGGGCCCTAAAGCAACACGACCAG
  CGTCCTAAAAAGACTACGTGAAGAGAAGGGCACCCAGAAGGAAGACCACCTGAAGATACA
  GGGAGGGGGCAGCTGTCTCAGGGAACACCAAAGATACCANCAGATGCCAGGAGAAAGCCA
  GGACAGGTTTTCCATTGCAACCTCAAGAGGAACCAGCCCTGGCAGCACCTTTCTTTTAGA
  CTTCTGGTCTTCAAAACCACGTGGCAGTACCTCTTTGCTGGCATGCCACTGGTTCTGGGA
  ACTCATTTCAGCAGCCCTACCTGATTCCACTGCCGATCATACAATGGGGCCCACCTGGGT
  TTCANTAGATNAAGTTTCCAAGAAACCCCAAAGACCTGCAAATTTACCGACCCAATGGTT
  ACCTGAAACATCAACGGCCTTTTGAATATAGATTAGGGAGGGCGCGCTGTGGTAACCTTG
  GGGGCTTACTAACCTTGGAGTGGGCCAGGAAACCGGGTCGATA
  
• Restriction Sites: ECoRI-NOT
• ACCN: NM_021709
• ORF Size: 333 bp
• Insert Size: 3670
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_021709.1, NP_068355.1
• RefSeq Size: 595
• RefSeq ORF: 333
• Locus ID: 10572
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes an E3 ubiquitin ligase that regulates cell cycle progression, cell proliferation and apoptosis. The N-terminus of this protein binds to the cytoplasmic tail of the CD27 antigen, a member of the tumor necrosis factor receptor (TNFR) superfamily. In response to UV radiation-induced DNA damage, this protein has been shown to mediate the ubiquitination of proliferating cell nuclear antigen (PCNA), an important step in translesion DNA synthesis. [provided by RefSeq, Sep 2018]
  Transcript Variant: This variant (2) lacks an alternate in-frame segment, compared to variant 1. It appears to lack the apoptotic properties of Siva. The resulting protein (isoform 2) is shorter when it is compared to isoform 1.