ATP dependent metalloprotease YME1L1 (YME1L1) (NM_014263) Human Untagged Clone

CAT#: SC110195

YME1L1 (untagged)-Human YME1-like 1 (S. cerevisiae) (YME1L1), nuclear gene encoding mitochondrial protein, transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: YME1L1
• Synonyms: FTSH; MEG4; OPA11; PAMP; YME1L
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC110195 sequence for NM_014263 edited (data generated by NextGen Sequencing)
  ATGTTTTCCTTGTCGAGCACGGTGCAACCCCAGGTTACAGTTCCTCTGAGTCATCTCATC
  AATGCCTTCCATACACCAAAAAACACTTCTGTTTCTCTCAGTGGAGTGTCAGTTTCTCAA
  AACCAGCATCGAGATGTAGTTCCTGAGCATGAGGCTCCCAGCAGTGAGCCTTCACTTAAC
  TTAAGGGACCTTGGATTATCTGAACTAAAAATTGGACAGATTGATCAGCTGGTAGAAAAT
  CTACTTCCTGGATTTTGTAAAGGCAAAAACATTTCTTCCCATTGGCATACATCCCATGTC
  TCTGCACAATCCTTCTTTGAAAATAAATATGGTAACTTAGATATATTTAGTACATTACGT
  TCCTCTTGCTTGTATCGACATCATTCAAGAGCTCTTCAAAGCATTTGTTCAGATCTTCAG
  TACTGGCCAGTTTTCATACAGTCTCGGGGTTTTAAAACTTTGAAATCAAGGACACGACGT
  CTCCAGTCTACCTCCGAGAGATTAGCTGAAACACAGAATATAGCGCCATCATTCGTGAAG
  GGGTTTCTTTTGCGGGACAGAGGATCAGATGTTGAGAGTTTGGACAAACTCATGAAAACC
  AAAAATATACYTGAAGCTCACCAAGATGCATTTAAAACTGGTTTTGCGGAAGGTTTTCTG
  AAAGCTCAAGCACTCACACAAAAAACCAATGATTCCCTAAGGCGAACCCGTCTGATTCTC
  TTCGTTCTGCTGCTATTCGGCATTTATGGACTTCTAAAAAACCCATTTTTATCTGTCCGC
  TTCCGGACAACAACAGGGCTTGATTCTGCAGTAGATCCTGTCCAGATGAAAAATGTCACC
  TTTGAACATGTTAAAGGGGTGGAGGAAGCTAAACAAGAATTACAGGAAGTTGTTGAATTC
  TTGAAAAATCCACAAAAATTTACTATTCTTGGAGGTAAACTTCCAAAAGGAATTCTTTTA
  GTTGGACCCCCAGGGACTGGAAAGACACTTCTTGCCCGAGCTGTGGCGGGAGAAGCTGAT
  GTTCCTTTTTATTATGCTTCTGGATCCGAATTTGATGAGATGTTTGTGGGTGTGGGAGCC
  AGCCGTATCAGAAATCTTTTTAGGGAAGCAAAGGCGAATGCTCCTTGTGTTATATTTATT
  GATGAATTAGATTCTGTTGGTGGGAAGAGAATTGAATCTCCAATGCATCCATATTCAAGG
  CAGACCATAAATCAACTTCTTGCTGAAATGGATGGTTTTAAACCCAATGAAGGAGTTATC
  ATAATAGGAGCCACAAACTTCCCAGAGGCATTAGATAATGCCTTAATACGTCCTGGTCGT
  TTTGACATGCAAGTTACAGTTCCAAGGCCAGATGTAAAAGGTCGAACAGAAATTTTGAAA
  TGGTATCTCAATAAAATAAAGTTTGATCAATCCGTTGATCCAGAAATTATAGYTCGAGGT
  ACTGTTGGCTTTTCCGGAGCAGAGTTGGAGAATCTTGTGAACCAGGCTGCATTAAAAGCA
  GCTGTTGATGGAAAAGAAATGGTTACCATGAAGGAGCTGGAGTTTTCCAAAGACAAAATT
  CTAATGGGGCCTGAAAGAAGAAGTGTGGAAATTGATAACAAAAACAAAACCATCACAGCA
  TATCATGAATCTGGTCATGCCATTATTGCATATTACACAAAAGATGCAATGCCTATCAAC
  AAAGCTACAATCATGCCACGGGGGCCAACACTTGGACATGTGTCCCTGTTACCTGAGAAT
  GACAGATGGAATGAAACTAGAGCCCAGCTGCTTGCACAAATGGATGTTAGTATGGGAGGA
  AGAGTGGCAGAGGAGCTTATATTTGGAACCGACCATATTACAACAGGTGCTTCCAGTGAT
  TTTGATAATGCCACTAAAATAGCAAAGCGGATGGTTACCAAATTTGGAATGAGTGAAAAG
  CTTGGAGTTATGACCTACAGTGATACAGGGAAACTAAGTCCAGAAACCCAATCTGCCATC
  GAACAAGAAATAAGAATCCTTCTAAGGGACTCATATGAACGAGCAAAACATATCTTGAAA
  ACTCATGCAAAGGAGCATAAGAATCTCGCAGAAGCTTTATTGACCTATGAGACTTTGGAT
  GCCAAAGAGATTCAAATTGTTCTTGAGGGGAAAAAGTTGGAAGTGAGATGA
  
  Clone variation with respect to NM_014263.2
  611 c=>y;1433 c=>y
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014263 unedited
  CAGCATTTTGTAATCACGACTCACTATAGGGCGGCCGCGCATTCGGCACGAGGGGCAACG
  GGTCGGAGAAAAAGGAAAAAAGAGGGCTCAGCGCCTCCCCGCCGGGCCGTGGACAGAGGG
  GCACAGTTTCGGCAGGCGGGTGAGGTCGCTGAGGGCCCGCCGGAGATGTTTTCCTTGTCG
  AGCACGGTGCAACCCCAGGTTACAGTTCCTCTGAGTCATCTCATCAATGCCTTCCATACA
  CCAAAAAACACTTCTGTTTCTCTCAGTGGAGTGTCAGTTTCTCAAAACCAGCATCGAGAT
  GTAGTTCCTGAGCATGAGGCTCCCAGCAGTGAGCCTTCACTTAACTTAAGGGACCTTGGA
  TTATCTGAACTAAAAATTGGACAGATTGATCAGCTGGTAGAAAATCTACTTCCTGGATTT
  TGTAAAGGCAAAAACATTTCTTCCCATTGGCATACATCCCATGTCTCTGCACAATCCTTC
  TTTGAAAATAAATATGGTAACTTAGATATATTTAGTACATTACGTTCCTCTTGCTTGTAT
  CGACATCATTCAAGAGCTCTTCAAAGCATTTGTTCAGATCTTCAGTACTGGCCAGTTCTC
  ATACAGTCTCGGGNGTTTAAAACTTTGAAATCAAGGACACGACGTCTCCATTCTACCTCC
  GAGAGATTACCTGAAACACAGAATATAGCGCCATCTTTCGTGAAGGGGTTTCTTTTGCGG
  GACAAAGGATCAGATGTTGAGAGTTCGGACACACTCATGAAAACCACCATATACTTGAAG
  CTCACCAAGAGCATTTAANACTGGTTTGCGGAAAGGTTTCTGAAAGCCCACCCCTTACCC
  AAANACCATTGATTCCTTAAGGCAACCCGTGTGAATCTCTCCGTTTGCTGTTATCCGGAT
  TTTTGGACTCTCAANAACCCATTCTTCCTTGCCGCTTC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_014263 unedited
  CGGGCCGCAATCTAGAATCGAGTTTTTTTTTTTTTTTTTTGGGGACTGAGATTTTTGTTT
  AATTTTGCTTTTGAAACCAAGCACAGTTATAGTCAAAATGAGGGACATTATTCAGAATGA
  GGTTATGTATTTATTTAACAAAATACTGCTTCTCTGAAGTACATTTCATTAGGGAGAGTG
  ACAGTAATGCTAAAAAAAAGAACATGAAAATGCACACAGCATTTCTGAAAGGGTATAATA
  ATTTATTTAATTTTTTTTTGAGACAGAGTCTCACTCTGTCACCCAAGCTGGAGTGCAGTG
  GCTCCTGTGATCTTGGCTCACTGCAACCTCCACCTCCTGGGTTCAAGCAATTCTCGTGCC
  TCAGCCTCTCAAGTAGCTGGGATTCCAGGCATGCACCCCACACCTGGCTATTTTTTTTTG
  TATTTAAATTTATTTTAATTTTTTTTTGAGGCAGAGTCTTGCTCTGTTGCCCAAGCTGGA
  GTGCAGTGGCATGATCTCAGCTCACTGCAACCTCCATCTCCCAGGCTCAAGCAATTCTCC
  TGCCTTGGCCCCCAGAGTAGCTGGGATTATAAGCACCTGCCACCATGCCCAGGTAATTTT
  TGCATGTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAAGCTGGTCTCAAACTCTTGAC
  CTCANGTGATTTGCCCGCCTTGGCCTCTGAAAGTGCTGGGATACAGGCGTGAGCAACCGC
  GCCCAGCCCTATTTTTTTGTATTTTAGTAGAGACAGCCGTTCACACGTTGGCCAAGCTGG
  TCTCGAACTCCTGGCCTCAAGCCATCCACCCGCCTCAGCCTCCAAAAGTGCTGGGATTAC
  AGATGGGAGCCATGCCCCCTGCCCAAAGGCTATATTCTGGCTCTGAGTTTCCAAGACTGC
  TTTTAATCCCACTCTTTACATTAGATTAAAAAATTTTATCATTGGCAATCGGAACAATTA
  CTGCTCCTAGTCCN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_014263
• ORF Size: 2151 bp
• Insert Size: 3080
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_014263.2, NP_055078.1
• RefSeq Size: 3865
• RefSeq ORF: 2151
• Locus ID: 10730
• Domains: Peptidase_M41, AAA, AAA
• Protein Families: Druggable Genome, Protease
• Gene Summary: The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
  Transcript Variant: This variant (3) lacks an internal coding exon compared to transcript variant 1. However, it maintains the same reading frame, and encodes an isoform (3) that is missing a 57 aa segment compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.