MSL3L1 (MSL3) (NM_006800) Human Untagged Clone

CAT#: SC110205

MSL3 (untagged)-Human male-specific lethal 3 homolog (Drosophila) (MSL3), transcript variant 3


  "NM_006800" in other vectors (4)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol MSL3
Synonyms MSL3L1
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC110205 sequence for NM_006800 edited (data generated by NextGen Sequencing)
ATGGAAGAAAGAACAATAACTATAGAAATCCCTGAAGTTCTGAAGAAGCAGCTGGAGGAT
GATTGTTACTACATTAACAGGAGGAAACGGTTAGTGAAACTTCCATGCCAGACCAACATC
ATAACGATTTTGGAATCCTATGTGAAGCATTTTGCTATCAATGCAGCCTTTTCAGCCAAT
GAGAGGCCTCGTCACCATCACGTTATGCCACATGCCAACATGAACGTGCATTATATCCCA
GCAGAAAAGAATGTTGACCTTTGTAAGGAGATGGTGGATGGATTAAGAATAACCTTTGAT
TACACTCTCCCGTTGGTTTTACTCTATCCATATGAACAAGCTCAGTATAAAAAGGTGACT
TCGTCTAAATTTTTTCTTCCAATTAAGGAAAGTGCCACAAGCACTAACAGGAGCCAGGAG
GAACTCTCTCCCAGTCCGCCTTTGTTGAATCCATCCACGCCACAGTCCACAGAGAGTCAG
CCGACCACCGGTGAACCAGCCACCCCCAAAAGGCGCAAAGCTGAGCCAGAAGCATTGCAG
TCTCTGAGGCGGTCCACGCGCCACAGTGCCAACTGTGACAGGCTTTCTGAGAGCAGCGCT
TCACCTCAGCCCAAGCGCCGGCAGCAGGACACATCCGCCAGCATGCCCAAGCTCTTCCTG
CACCTGGAAAAGAAGACACCTGTGCATAGCAGATCATCTTCACCTATTCCTCTGACTCCT
AGCAAGGAAGGGAGTGCTGTGTTTGCTGGCTTTGAAGGGAGAAGAACTAATGAAATAAAC
GAGGTCCTCTCCTGGAAGCTTGTGCCTGACAATTACCCCCCAGGTGACCAGCCGCCTCCA
CCCTCTTACATTTATGGGGCACAACATTTGCTGCGATTGTTTGTGAAACTTCCAGAAATC
CTTGGAAAGATGTCCTTTTCTGAGAAGAATCTGAAGGCTTTATTGAAGCACTTTGATCTC
TTTTTGAGGTTTTTAGCAGAATACCACGATGACTTCTTCCCAGAGTCGGCTTATGTCGCT
GCCTGTGAGGCACATTACAGCACCAAGAACCCCCGGGCAATTTATTAA

Clone variation with respect to NM_006800.3
>OriGene 5' read for NM_006800 unedited
TACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGAGCGCGAGCGAGGGCATGAAA
TTTAAATTCCACTCAGGGGAGAAAGTGCTGTGCTTCGAGCCTGACCCCACCAAGGCGCGA
GTGCTGTACGATGCCAAGATTGTTGATGTTATTGTTGGGAAAGACGAAAAAGGCAGAAAG
ATCCCAGAATATCTGATCCATTTTAATGGTTGGAACAGAAGCTGGGATAGATGGGCAGCA
GAAGATCATGTGCTTCGTGATACCGATGAAAATCGTAGATTACAGCGTAAATTGGCAAGA
AAAGCTGTAGCTCGCCTGAGGAGCACAGGAAGAAAGAAGAAGCGCTGCAGGTTGCCTGGT
GTGGACTCTGTCTTAAAAGGCCTCCCCACTGAAGAAAAAGATGAAAATGATGAAAACTCA
TTAAGCAGTTCCTCTGACTGTAGTGAAAACAAGGATGAAGAAATAAGTGAAGAAAGTGAT
ATTGAAGAAAAGACTGAAGTGAAAGAAGAACCAGAGCTTCAAACAAGAAGGGAAATGGAA
GAAAGAACAATAACTATAGAAATCCCCTGAAGTTCTGAAGAAGCAGCTGGAGGATGATTG
TTACTACATTAACAGGAGGAAACGGTTAGTGAAACTTCCATGCCAGACCAACATCATAAA
CGATTTGGAATNCTATGTGAAGCATTTTGCTATCAATGCAGCCTTTTCAGCCAATGAGAG
GCCTCGTCACCATCACGTTATGCCACATGCCAACATGAACGTGCATTATATCCCAGCAGA
AAAGAATGTTGACCTTTGTANGGAGNATGNNGGATGGATAANAAATAACCTTTGATTACA
CTCTCCCGGTGGNTTTTACTCTATCCATAATGACAAGCTCAGTTTAAAAAGGTGACCTCG
CCTAAATTTTTTCTCCAATTAAGAAAAGTGCCCCAGCCCTATCCGGAGCCCGAAGTACTT
TTTCCCATCCGGCCTTGTTGATTCCTCCCCGCCCCAGTCCAAGGAG
>OriGene 3' read for NM_006800 unedited
ATGGACCGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCTTTCAAACAAG
AACAGGCTTTATTTAGATCACCAAAAATAACATTTTACAGAAAGGGAACCATAACATTAC
ACAACAAAGTATAGCTGTAAAATCTCAAATAAGAAAGGCAATGCTTTCTTTAGATCACCA
AAAATAATGTTTCACAGAGAGGGAACCGTTAGAAGCAAATGCATAGCTGCAAATTTTCTT
TTGCCATCAATATCGATTCCCTCTAAAATACTTTGAGACTACTTTGTGGTTTCCGAGTAC
AAACTAAACCTTTTTGGACAGAGTTGCTCGGCTTCATCAAAAAAATAAAACCAATTTGCA
AAAAAAATTTGTTTAATGCTAACAAATAAAGAGACAATGTGGTTCTTGCTAACTAACTGC
AATGTCTACTGAAATGGCCTAACCTATTCCACGAATATTTCACTGTGAACATAGTTGCTT
TTTCCTTGCCATCACAGATGGCCTGCAAAGTAACAAGTGTCGTGTCAGAGCACTTTCAGG
CACCCAGGGAATCATTCCTAACAGAATAACTGCAGTATGTGGGCAACTCAAACAACAGAG
CCCCAAGGTGGGCATTGTGTTTGCGCTGTGGGTAAAGACCCACCACCTTGTTAGTTATTC
ACCCTGGACCCAGAGCGCCAAACTAGACAGAGCAGTTGCTCTTACAGAACCAACAACATT
NTAATAAATTGCCCGGGGGGTCTTGGTGCTGNTATGTGCCTCACAGGCAGCGACATAAGC
CGACTCTGGGAAAGAGTCATCGTGGTATTCTGCTAAAAACTCAAAAGAGATCAAGTGCTT
CATAAAGCCTTCAGATNCTCTAGAAAAGACATCTTTCAGGATTTCTGGAAGTTCACAACA
TCGCACAATGTTGTGCCCATAATGC
Restriction Sites NotI-NotI     
ACCN NM_006800
ORF Size 1068 bp
Insert Size 2340
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_006800.2, NP_006791.2
RefSeq Size 2305
RefSeq ORF 1068
Locus ID 10943
Protein Families Transcription Factors
Gene Summary This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. [provided by RefSeq, Jul 2010]
Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream start codon, compared to variant 1. The resulting isoform (c) is 166 aa shorter shorter at the N-terminus, compared to isoform a.

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