Kallikrein 11 (KLK11) (NM_006853) Human Untagged Clone

CAT#: SC110209

KLK11 (untagged)-Human kallikrein-related peptidase 11 (KLK11), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KLK11
• Synonyms: PRSS20; TLSP
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_006853, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGGATTCTGCAGTTAATCCTGCTTGCTCTGGCAACAGGGCTTGTAGGGGGAGAGACCAGGATCATCA
  AGGGGTTCGAGTGCAAGCCTCACTCCCAGCCCTGGCAGGCAGCCCTGTTCGAGAAGACGCGGCTACTCTG
  TGGGGCGACGCTCATCGCCCCCAGATGGCTCCTGACAGCAGCCCACTGCCTCAAGCCCCGCTACATAGTT
  CACCTGGGGCAGCACAACCTCCAGAAGGAGGAGGGCTGTGAGCAGACCCGGACAGCCACTGAGTCCTTCC
  CCCACCCCGGCTTCAACAACAGCCTCCCCAACAAAGACCACCGCAATGACATCATGCTGGTGAAGATGGC
  ATCGCCAGTCTCCATCACCTGGGCTGTGCGACCCCTCACCCTCTCCTCACGCTGTGTCACTGCTGGCACC
  AGCTGCCTCATTTCCGGCTGGGGCAGCACGTCCAGCCCCCAGTTACGCCTGCCTCACACCTTGCGATGCG
  CCAACATCACCATCATTGAGCACCAGAAGTGTGAGAACGCCTACCCCGGCAACATCACAGACACCATGGT
  GTGTGCCAGCGTGCAGGAAGGGGGCAAGGACTCCTGCCAGGGTGACTCCGGGGGCCCTCTGGTCTGTAAC
  CAGTCTCTTCAAGGCATTATCTCCTGGGGCCAGGATCCGTGTGCGATCACCCGAAAGCCTGGTGTCTACA
  CGAAAGTCTGCAAATATGTGGACTGGATCCAGGAGACGATGAAGAACAATTAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006853 unedited
  TGCACCATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGTGCTG
  TGAGAAACAGGGGATTTCCCCACCTTGTTTCTCCCAATGGGGAGCGGGAGCAGAGGAACC
  TGGGGCCCGCTCCTCCCCCCTCCAGGCCATGAGGATTCTGCAGTTAATCCTGCTTGCTCT
  GGCAACAGGGCTTGTAGGGGGAGAGACCAGGATCATCAAGGGGTTCGAGCGCAAGCCTCA
  CTCCCAGCCCTGGCAGGCAGCCCTGTTCGAGAAGACGCGGCTACTCTGTGGGGCGACGCT
  CATCGCCACCAGATGGCTCCTGACAGCAGCCCACTGCCTCAAGCCCCGCTACATAGTTCA
  CCTGGGGCAGCACAACCTCCAGAAGGAGGAGGGCTGTGAGCAGACCCGGACAGCCACTGA
  GTCCTTCCCCCACCCCGGCTTCAACAACAGCCTCCCCAACAAAGACCACCGCAATGACAT
  CATGCTGGTGAAGATGGCATCGCCAGTCTCCATCACCTGGGCTGTGCGACCCCTCACCCT
  CTCCTCACGCTGTGTCACTGCTGGCACCAGCTGCCTCATTTCCGGCTGGGGCAGCACGTC
  CAGCCCCCAGTTACGCCTGCCTCACACCCTTGCGATGCGCCAACATCACCATCATTGAGC
  ACCCAGAAGTGTGAGAACGCCTACCCCGGAACATCACAGACACCATGGTGTGTGCCACCG
  TGCAAGAAGGGGGCAAGGCTCCTGTCAGGTGACTCCGCGGGCCCTCTGGCCTGTACCAAT
  CCTTTCAAAGCATTAATCTCCGGGGCCCAGGATCCGTGTGCGATCACCCCAAAGCCTGGT
  GTCTACCGAAAGTCTGCAAATATGCGGCCCGGATCCAGGCACACATGAACAAACAATTAA
  ACTGGACCCCCCCCCCAAGTCCATTACCCTCAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006853 unedited
  TTTTACGAGTTTTTTGCAAACTTGNTATATGGGCCGGNACTGTCTTTGGGGCTGGGGATC
  AACAGAGAACAACCAGGTGTTGTCATTCCCAGAGTCACAATATTTCAAGGCAGAATTTGA
  ATCCAGGTCTCACTGATTTCGAACCCCAGGTTGATTATTAAGTGACAGCATCTCCTGTAG
  TCCAGGAGGCCCAAAGAATGTTCGTAGAGGGTCTTGGCTTAGGGTTTCTTATTAACAGAG
  TGAACAGGAACCAAACACCAAGTGGAAATGGAGGGTGATGGGCTGTGGTGGGTGGGTCCA
  GTCTAATTGTTCTTCATCGTCTCCTGGATCCAGTCCACATATTTGCAGACTTTCGTGTAG
  ACACCAGGCTTTCGGGTGATCGCACACGGATCCTGGCCCCAGGAGATAATGCCTTGAAGA
  GACTGGTTACAGACCAGAGGGCCCCCGGAGTCACCCTGGCAGGAGTCCTTGCCCCCTTCC
  TGCACGCTGGCACACACCATGGTGTCTGTGATGTTGCCGGGGTAGGCGTTCTCACACTTC
  TGGTGCTCAATGATGGTGATGTTGGCGCATCGCAAGGTGTGAGGCAGGCGTAACTGGGGG
  CTGGACGTGCTGCCCCAGCCGGAAATGAGGCAGCTGGTGCCAGCAGTGACACANCGTGAG
  GAGAGGGTGAGGGGTCGCACAGCCCCAGTGATGGAGACTGGCGATGCCATCTTCACCAGC
  ATGATGTCATTGCGGTGGTCTTTGTTGGGAGGGCTGTTGTGAAGCCGGGTGGGGGAGGAC
  TCATGGCTGTCCGGTCTGTCACANCCTCCTCCTCTGGAGTTGTGCTGCCCAGTTGACTTG
  TACCGGGCTTGAGCCATGGCTGCTGCCAGACCATCTGGGGCGAGAGGTCGCCCCAGATAA
  CCGGTCTTTC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006853
• ORF Size: 753 bp
• Insert Size: 1330
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006853.2, NP_006844.1
• RefSeq Size: 1207
• RefSeq ORF: 753
• Locus ID: 11012
• Domains: Tryp_SPc
• Protein Families: Druggable Genome, Protease, Secreted Protein
• Gene Summary: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing and the use of alternate promoters results in multiple transcript variants encoding distinct isoforms which are differentially expressed. [provided by RefSeq, Dec 2016]
  Transcript Variant: This variant (1) has an alternate 5' terminal exon, which results in a downstream translation start codon, compared to variant 2. The encoded isoform (1) has a shorter N-terminus than isoform 2, and is preferentially expressed in brain. Variants 1 and 4 encode the same isoform 1.