POFUT1 (NM_172236) Human Untagged Clone

CAT#: SC110314

POFUT1 (untagged)-Human protein O-fucosyltransferase 1 (POFUT1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: POFUT1
• Synonyms: DDD2; FUT12; O-Fuc-T; O-FucT-1; O-FUT; OFUCT1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_172236, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGCGCCGCCGCGTGGGCACGGCCGCTGAGCGTGTCTTTCCTGCTGCTGCTTCTGCCGCTCCCGGGGA
  TGCCTGCGGGCTCCTGGGACCCGGCCGGTTACCTGCTCTACTGCCCCTGCATGGGGCGCTTTGGGAACCA
  GGCCGATCACTTCTTGGGCTCTCTGGCATTTGCAAAGCTGCTAAACCGTACCTTGGCTGTCCCTCCTTGG
  ATTGAGTACCAGCATCACAAGCCTCCTTTCACCAACCTCCATGTGTCCTACCAGAAGTACTTCAAGCTGG
  AGCCCCTCCAGGCTTACCATCGGGTCATCAGCTTGGAGGATTTCATGGAGAAGCTGGCACCCACCCACTG
  GCCCCCTGAGAAGCGGGTGGCATACTGCTTTGAGGTGGCAGCCCAGCGAAGCCCAGATAAGAAGACGTGC
  CCCATGAAGGAAGGAAACCCCTTTGGCCCATTCTGGGATCAGTTTCATGTGAGTTTCAACAAGTCGGAGC
  TTTTTACAGGCATTTCCTTCAGTGCTTCCTACAGAGAACAATGGAGCCAGAGGCGTGAGAATCACTCCTG
  TGTTACCTTACTCTTCCCAAGGTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_172236 unedited
  GTATACGACTCCTATAGGCGGCCGCGAATTCGGCACGAGGCCGACTGTGCGCCGCGGCTG
  GCTCGGGTTCCCGGGCCGACTGGGCGCCGCCGCGTGGGCACGGCCGCTGAGCGTGTCTTT
  CCTGCTGCTGCTTCTGCCGCTCCCGGGGATGCCTGCGGGCTCCTGGGACCCGGCCGGTTA
  CCTGCTCTACTGCCCCTGCATGGGGCGCTTTGGGAACCAGGCCGATCACTTCTTGGGCTC
  TCTGGCATTTGCAAAGCTGCTAAACCGTACCTTGGCTGTCCCTCCTTGGATTGAGTACCA
  GCATCACAAGCCTCCTTTCACCAACCTCCATGTGTCCTACCAGAAGTACTTCAAGCTGGA
  GCCCCTCCAGGCTTACCATCGGGTCATCAGCTTGGAGGATTTCATGGAGAAGCTGGCACC
  CACCCACTGGCCCCCTGAGAAGCGGGTGGCATACTGCTTTGAGGTGGCAGCCCAGCGAAG
  CCCAGATAAGAAGACGTGCCCCATGAAGGAAGGAAACCCCTTTGGCCCATTCTGGGATCA
  GTTTCATGTGAGTTTCAACAAGTCGGAGCTTTTTACAGGCATTTCCTTCAGTGCTTCCTA
  CAGAGAACAATGGAGCCAGAGATTNTCTCCAAAGGAACATCCGGTGCTTGCCCTGCCAGG
  AGCCCCAGCCCAGTTCCCCGTCCTAGAGGAACACAGGCCACTACAGAAGTACATGGTATG
  GTCAGACGAAATGGTGAAGACGGGAGAAGGCCANNATCATGCCCACCTTGTNCCGCCCTA
  TGTGGGCATTCATCTGCGCATTGGCTCTGACTGGAAGAACGCTGTGCATGCTNGANGACN
  NGGACTGCAGCTCGCACTTATGGCCCTTCCGCAGGGTGTGGGCTACAGNCCAGCACAGCG
  GCCCCCTCAGN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_172236
• ORF Size: 585 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_172236.1, NP_758436.1
• RefSeq Size: 1524
• RefSeq ORF: 585
• Locus ID: 23509
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) uses an alternate exon in the 3' coding region and 3' UTR, compared to variant 1. Isoform 2 has a shorter and distinct C-terminus, compared to isoform 1.