WWOX (NM_130791) Human Untagged Clone

CAT#: SC110463

WWOX (untagged)-Human WW domain containing oxidoreductase (WWOX), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: WWOX
• Synonyms: D16S432E; EIEE28; FOR; FRA16D; HHCMA56; PRO0128; SCAR12; SDR41C1; WOX1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_130791, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCAGCGCTGCGCTACGCGGGGCTGGACGACACGGACAGTGAGGACGAGCTGCCTCCGGGCTGGGAGG
  AGAGAACCACCAAGGACGGCTGGGTTTACTACGCCAATCACACCGAGGAGAAGACTCAGTGGGAACATCC
  AAAAACTGGAAAAAGAAAACGAGTGGCAGGAGATTTGCCATACGGATGGGAACAAGAAACTGATGAGAAC
  GGACAAGTGTTTTTTGTTGACCATATAAATAAAAGAACCACCTACTTGGACCCAAGACTGGCGTTTACTG
  TGGATGATAATCCGACCAAGCCAACCACCCGGCAAAGATACGACGGCAGCACCACTGCCATGGAAATTCT
  CCAGGGCCGGGATTTCACTGGCAAAGTGGTTGTGGTCACTGGAGCTAATTCAGGAATAGGGTTCGAAACC
  GCCAAGTCTTTTGCCCTCCATGGTGCACATGTGATCTTGGCCTGCAGGAACATGGCAAGGGCGAGTGAAG
  CAGTGTCACGCATTTTAGAAGAATGGAAAACAAAATACCACCCTCCGCCAGAAAAGTGCAGAATAAAAAT
  TTTCCACTAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_130791 unedited
  GGAATTTGTAATACGACTCACTATAGGGCGGCCGCGACATCGGCACGAGGTGAGTTCCTG
  AGCGAGTGGACCCGGCAGCGGGCGATAGGGGGGCCAGGTGCCTCCACAGTTAGCCATGGC
  AGCGCTGCGCTACGCGGGGCTGGACGACACGGACAGTGAGGACGAGCTGCCTCCGGGCTG
  GGAGGAAAGAACCACCAAGGACGGCTGGGTTTACTACGCCAATCACACCGAGGAGAAGAC
  TCAGTGGGAACATCCAAAAACTGGAAAAAGAAAACGAGTGGCAGGAGATTTGCCATACGG
  ATGGGAACAAGAAACTGATGAGAACGGACAAGTGTTTTTTGTTGACCATATAAATAAAAG
  AACCACCTACTTGGACCCAAGACTGGCGTTTACTGTGGATGATAATCCGACCAAGCCAAC
  CACCCGGCAAAGAATACGAACGGCAGCACCACTGCCATGGAAATTCTCCAGGGCCGGGAT
  TTCACTGGCAAAGTGGTTGTGGTCACTGGAGCTAATTCAGGAATAGGGTTCGAAACCGCC
  AAGTCTTTTGCCCTCCATGGTGCACATGTGATCTTGGCCTGCAGGAACATGGCAAGGGCG
  AGTGAAGCAGTGTCACGCATTTTAGAAGAATGGCATAAAGCCAAGGTAGAAGCAATGACC
  CTGGACCTCGCTCTGCNTCGTAGCGTGCAGCATTNTGCTGAAGCATTCAAGCCAAGAATG
  TGCCTCTTCATGTGCTTGTGTGCAACGCAGCAACTTTTGCTCTACCCTGGAGTCTCACCA
  AGATGGCCTGNAGAACACCTTTTCAGTGAATCATCTGGNGCACTTCTACCTTGTNCAGCT
  CTNCAGAATGNNTTGTGCGCTCACTCTGCCGTGTCATTGGGNCTCCTCAAATCCATCGAT
  TACAGATATAACGACTCTTGGAAAATGGNACTCATCGCTCTCTCAAAAAACATATGGNCG
  ATGCTGCTATACAGTCAGCTTGACATCTTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_130791
• ORF Size: 570 bp
• Insert Size: 2550
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_130791.1, NP_570607.1
• RefSeq Size: 735
• RefSeq ORF: 570
• Locus ID: 51741
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
  Transcript Variant: This variant (2) lacks several exons and uses an alternate 3'-terminal exon, compared to variant 1. The encoded isoform (2) has a shorter and distinct C-terminus, compared to isoform 1.