DPM3 (NM_153741) Human Untagged Clone

CAT#: SC110478

DPM3 (untagged)-Human dolichyl-phosphate mannosyltransferase polypeptide 3 (DPM3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DPM3
• Synonyms: CDG1O
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC110478 sequence for NM_153741 edited (data generated by NextGen Sequencing)
  ATGACGAAATTAGCGCAGTGGCTTTGGGGACTAGCGATCCTGGGCTCCACCTGGGTGGCC
  CTGACCACGGGAGCCTTGGGCCTGGAGCTGCCCTTGTCCTGCCAGGAAGTCCTGTGGCCA
  CTGCCCGCCTACTTGCTGGTGTCCGCCGGCTGCTATGCCCTGGGCACTGTGGGCTATCGT
  GTGGCCACTTTTCATGACTGCGAGGACGCCGCACGCGAGCTGCAGAGCCAGATACAGGAG
  GCCCGAGCCGACTTAGCCCGCAGGGGGCTGCGCTTCTGA
  
  Clone variation with respect to NM_153741.1
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_153741 unedited
  NGTTCAAATTTTGTATACGACTCACTATAGGCGGCCGCGATTCGGCACGAGCGGGGAAGG
  GGAGACGTGGGGTAGAGTGACCATGACGAAATTAGCGCAGTGGCTTTGGGGACTAGCGAT
  CCTGGGCTCCACCTGGGTGGCCCTGACCACGGGAGCCTTGGGCCTGGAGCTGCCCTTGTC
  CTGCCAGGAAGTCCTGTGGCCACTGCCCGCCTACTTGCTGGTGTCCGCCGGCTGCTATGC
  CCTGGGCACTGTGGGCTATCGTGTGGCCACTTTTCATGACTGCGAGGACGCCGCACGCGA
  GCTGCAGAGCCAGATACAGGAGGCCCGAGCCGACTTAGCCCGCAGGGGGCTGCGCTTCTG
  ACAGCCTAACCCCATTCCTGTGCGGACAGCCCTTCCTCCCATTTCCCATTAAAGAGCCAG
  TTTATTTTCTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACCTCGCCTTTAAATGGGGGCCGGGGTC
  ATAGCTGTTTCCTGAACAAACCCCGGGGGGCATCCCTGTGACCCCTCCCAAGGGCCTTTC
  CTGGCCCTGGAAGTTGCCACTCCAGGGCCCACCACCCTTGTCCTAATAAAATAAAGTGGC
  ATCATTTTGTCTGACTAGGGGTCCTTTATATATTATGGGGTGGGGGGGGGGTTTTTTTAC
  CCCAAGGCCAATTTTGGAAAAAAACCTGAGGGCTTGCGGGGTCTTTGGGAACAGCTGAAG
  GCAGGGGCCAATTTTGCTATGCAATTCCTCCTCTGGGTCAGGGATTTTCTGCTACCTCCC
  AATTGTGGGATTCAGNATGCTGACAGCTAATAATTTGTTTTTTGTAAACCGGGTTTACCA
  ATGGACACTTGTTCCACTCTATTCAGGTATTACCCTTGCCTCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_153741 unedited
  AACTGGCTCTTTATGGGCAAAGGGAGGAGGGCTGTCCGCACAGNATGGGGTTAGGCTGTC
  AGAAGCGCAGCCCCCTGCGGGCTAAGTCGGCTCGGGCCTCCTGTATCTGGCTCTGCAGCT
  CGCGTGCGGCGTCCTCGCAGTCATGAAAAGTGGCCACACGATAGCCCACAGTGCCCAGGG
  CATAGCAGCCGGCGGACACCAGCAAGTACGCGGGCAGTGGCCACAGGACTTCCTGGCAGG
  ACAAGGGCAGCTCCAGGCCCAAGGCTCCCGTGGTCCTTGGTCACCTACATGGAAACCAAC
  ATGGCTACCCCCGCACGCCCCTAGCCCTCCCCCTCTCGCCGCCCCCTTCCTCCCTTGTCC
  CCCGCCCCCCCCCCCGTTTCCCCCCCTCCTTTTTTTCCCCCCTCCCGACCCCTTCTTTCC
  TTTTTCCTTCCCCCTTCCCACCCCCCGCCCCCGCCTTTCTCTTTTGTTCCCCCCCCCCCC
  GCCCCCGCCCGCCTTGCTCCGCCCCTCCCCCGTGTGTCTTCACCCCCCCACCCCCCGCCT
  CCCCGCCTTCCTTTCTTTCCGTTCTCCCCCACCCCTCTCCCGCGCCCCGCCCCCCCCCCC
  CTCCCTTTTTCCCCCCCTCCCCCCCCTCTCTTCTTTTTCCCCCATTCTGCAACCCCTCCC
  TCCCTTCCAGGCCGCGCCGGTGCAGCGCCCCCCACTCCCTCTTTTTTGTCCCCCCGCACC
  CTCTTTCTTGCCCTCTGCTTATTCTCCTTTTCTCCCCCATTCCCAACCCCACTGTTTCCT
  CGCTCCCCGCTCGCCCCCCCGCCCCTCTGTCGGCCCCCGCCTCCGCCAACCCGTTTCGCT
  TCTCCGCCCGTGCGCCCCCCCCCTATCTCTTTCCCCTCGCCCCGCGCCCGCTCGTCCCCT
  TATTCGACCGCTCGCCGTGGCGTTGTTCGAGCCGTCGCCCGCCGCCAGCCACGCCCCGTC
  CGACGTCCGAACGTAGTCTTCGCTCTCCTCCGCCCTCTTCGCCCTCGCTTCTGTTCTCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_153741
• ORF Size: 279 bp
• Insert Size: 460
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_153741.1, NP_714963.1
• RefSeq Size: 417
• RefSeq ORF: 279
• Locus ID: 54344
• Protein Families: Transmembrane
• Protein Pathways: Metabolic pathways, N-Glycan biosynthesis
• Gene Summary: Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a subunit of dolichyl-phosphate mannosyltransferase and acts as a stabilizer subunit of the dolichyl-phosphate mannosyltransferase complex. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) contains an alternate exon in the 5' UTR and 5' coding region, compared to variant 1. This results in translation initiation from a downstream ATG and an isoform (2) with a shorter N-terminus compared to isoform 1.