Aprataxin (APTX) (NM_017692) Human Untagged Clone

CAT#: SC110489

APTX (untagged)-Human aprataxin (APTX), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: APTX
• Synonyms: AOA; AOA1; aprataxin; ataxia 1, early onset with hypoalbuminemia; AXA1; EAOH; EOAHA; FHA-HIT; FLJ20157; MGC1072; OTTHUMP00000021188
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC110489 sequence for NM_017692 edited (data generated by NextGen Sequencing)
  ATGCAGGACCCCAAAATGCAGGTTTACAAAGATGAGCAGGTGGTGGTGATAAAGGATAAA
  TACCCAAAGGCCCGTTACCATTGGCTGGTCTTACCGTGGACCTCCATTTCCAGTCTGAAG
  GCTGTGGCCAGGGAACACCTTGAACTCCTTAAGCATATGCACACTGTGGGGGAAAAGGTG
  ATTGTAGATTTTGCTGGGTCCAGCAAACTCCGCTTCCGATTGGGCTACCACGCCATTCCG
  AGTATGAGCCATGTACATCTTCATGTGATCAGCCAGGATTTTGATTCTCCTTGCCTTAAA
  AACAAAAAACATTGGAATTCTTTCAATACAGAATACTTCCTAGAATCACAAGCTGTGATC
  GAGATGGTACAAGAGGCTGGTAGAGTAACTGTCCGAGATGGGATGCCTGAGCTCTTGAAG
  CTGCCCCTTCGTTGTCATGAGTGCCAGCAGCTGCTGCCTTCCATTCCTCAGCTGAAAGAA
  CATCTCAGGAAGCACTGGACACAGTGA
  
  Clone variation with respect to NM_017692.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_017692 unedited
  GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCGGAAGCGGTGAGGCA
  CAGATGAGTAACGTGAATTTGTCCGTCTCCGACTTCTGGAGAGTGATGATGCGGGTGTGC
  TGGTTGGTGAGACAGGACAGCCGGCACCAGCGAATCAGACTTCCACATTTGGAAGCAGTT
  GTGATTGGGCGTGGCCCAGAGACCAAGATCACTGATAAGAAATGTTCTCGACAGCAAGTT
  GAAAGCAGAGTGTAACAAGGGATATGTCAAGGTAAAGCAGGTAGGAGTCAATCCCACCAG
  CATTGACTCAGTCGTAATTGGGAAGGACCAAGAGGTGAAGCTGCAGCCTGGCCAGGTTCT
  CCACATGGTGAATGAACTTTATCCATATATTGTAGAGTTTGAGGAAGAGGCAAAGAACCC
  TGGCCTGGAAACACACAGGAAGAGAAAGAGATCAGGCAACAGTGATTCTATAGAAAGGGA
  TGCTGCTCAGGAAGCTGAGGCTGGGACAGGGCTGGAACCTGNGAGCAACTCTGGCCAATG
  CTCTGTGCCCCTAAAGAAGGGAAAAGATGCACCTATCAAAAAGGAATCCCTGGGCCACTG
  GAGTCAAGGCTTGAAGATTTCTATGCAGGACCCCAAAATGCAGGTTTACAAAGATGAGCA
  GGTGGTGGTGATAAAGGATAAATACCCAAAGGCCCGTTACCATTGGCTGGTCTTACCGTG
  GACCTCCATTTNCAGTCTGAAGGCTGNTGCCAGGGAACACCTTGNACTNCTTNAGCATAT
  GCACACTGNTGGGGAAANAGGGTGATGTANATNTTGCTGGGGTCANCANACTNCGCTTTC
  GATGGNGCTACCACGCCATTTCGAGTATGAGGCATGTACATCTTCATGTGATCAGCCAGG
  ATTTTGATCCTTCTTGCTTTAAACANAAACATTGGNATCTTTAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_017692 unedited
  ATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTACTGTTTTATCCAAATTTATTCTCAGGGA
  AAAAGAAAGTAGTGGCTCTACGCAACTTTTTCATTCACCAACCACCTTTCCATGCATCAG
  AACCTATGCTGTGATTGTTAGCTGAACTTCAATAGTTTCCACCTACTTAAGAGAGATGCC
  TCAAACAAATTAACTTTATTTTCAGACAACAGGTCCAAGAAGACTTCACAGCTCAATCAT
  GACGAACATGTGGCTGTTTCCTCACAGCCAGGAACCCTCGGTATTAGAAGAAAACTCCAA
  CCCCCCACACCATCATCTAGCCTCTTTTCTCACTGTGAAGAACTGATGAGACAGAATTCC
  TGAGAAGGGAACATTTAGGTAATCTGGGATAGAAGGGCATGGAAGGACTGGACAAACTAA
  GCCTCCCCATGAAGGAAGGGAAAAGAATATTACAAAACAGACTAACAGAAAACAAGACCC
  ATCAGTATCTTCAGGATAAACAAGAGGCCACTCTAGATGCTCTGATTAAAGGTTGTCCAT
  GCCTACAGAGGCGGAGGATAAATCTAAGACACAGAAATGTATAACCAGCCCAATGCTTCC
  ATACTCTGCATTAGGTCAGTGTGAACATGGGCTTGCTCCCATGGTCAGACCTGACATGGG
  TCCTTCTGAAGATGGTGGTCAGGTATACCCACCCCCCTCACCAAAATCCTTCTTGACAAC
  CCAATTCCTAATCTGAAGACTTGACCACTCTAATCGGGCCCCTTATATAGACAAATTGGG
  AAAAACTGCCTGTTTATTTAGGAAGGATAAAGTCCCAACTATCAAAATGGGGCCCCATTT
  GCTCCAGTGGCCCCACCCAGAACAGTCAGGCCTGGAAATACTTGGTCACGTTCCCTGAAG
  CCTTTCCCGAGGAGGAAGGAACTTGTTGCCCTCTACACCAGGGCCTCAAACCTGGCTCCT
  TTTGGAGTCTCTCACCTCTGCCTTCCGACAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_017692
• ORF Size: 507 bp
• Insert Size: 2090
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_017692.2, NP_060162.1
• RefSeq Size: 2016
• RefSeq ORF: 507
• Locus ID: 54840
• Domains: HIT, zf-C2H2
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in this gene have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010]
  Transcript Variant: This variant (4) contains multiple differences in the 5' UTR and coding region compared to variant 1. The resulting isoform (d) contains a shorter N-terminus compared to isoform a.