OSCAR (NM_133168) Human Untagged Clone

CAT#: SC110782

OSCAR (untagged)-Human osteoclast associated, immunoglobulin-like receptor (OSCAR), transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: OSCAR
• Synonyms: PIgR-3; PIGR3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_133168, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCCTGGTGCTGATCCTCCAGCTGCTGACCCTCTTCCCCCCAGCTTCATACCACCCTAAGCCATGGC
  TGGGAGCTCAGCCGGCTACAGTTGTGACCCCTGGGGTCAACGTGACCTTGAGATGCCGGGCACCCCAACC
  CGCTTGGAGATTTGGACTTTTCAAGCCTGGAGAGATCGCTCCCCTTCTCTTCCGGGATGTGTCCTCCGAG
  CTGGCAGAATTCTTTCTGGAGGAGGTGACTCCAGCCCAAGGGGGAAGTTACCGCTGCTGCTACCGAAGGC
  CAGACTGGGGGCCGGGTGTCTGGTCCCAGCCCAGCGATGTCCTGGAGCTGCTGGTGACAGAGGAGCTGCC
  GCGGCCGTCGCTGGTGGCGCTGCCCGGGCCGGTGGTGGGTCCTGGCGCCAACGTGAGCCTGCGCTGCGCG
  GGCCGCCTGCGGAACATGAGCTTCGTGCTGTACCGCGAGGGCGTGGCGGCCCCGCTGCAGTACCGCCACT
  CCGCGCAGCCCTGGGCCGACTTCACGCTGCTGGGCGCCCGCGCCCCCGGCACCTACAGCTGCTACTATCA
  CACGCCCTCCGCGCCCTACGTGCTGTCGCAGCGCAGCGAGGTGCTGGTCATCAGCTGGGAAGACTCTGGC
  TCCTCCGACTACACCCGGGGGAACCTAGTCCGCCTGGGGCTGGCCGGGCTGGTCCTCATCTCCCTGGGCG
  CGCTGGTCACTTTTGACTGGCGCAGTCAGAACCGCGCTCCTGCTGGTATCCGCCCCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_133168 unedited
  GTTCAGATTTTGTAATACGACTCACTATAGNNGGCGGCCGCGTGTATCCTCCAGCTGCTG
  ACCCTCTGGCCTCTGTGTCACACAGACATCACTCCGTCTGTCCCCCCAGCTTCATACCAC
  CCTAAGCCATGGCTGGGAGCTCAGCCGGCTACAGTTGTGACCCCTGGGGTCAACGTGACC
  TTGAGATGCCGGGCACCCCAACCCGCTTGGAGATTTGGACTTTTCAAGCCTGGAGAGATC
  GCTCCCCTTCTCTTCCGGGATGTGTCCTCCGAGCTGGCAGAATTCTTTCTGGAGGAGGTG
  ACTCCAGCCCAAGGGGGAAGTTACCGCTGCTGCTACCGAAGGCCAGACTGGGGGCCGGGT
  GTCTGGTCCCAGCCCAGCGATGTCCTGGAGCTGCTGGTGACAGAGGAGCTGCCGCGGCCG
  TCGCTGGTGGCGCTGCCCGGGCCGGTGGTGGGTCCTGGCGCCAACGTGAGCCTGCGCTGC
  GCGGGCCGCCTGCGGAACATGAGCTTCGTGCTGTACCGCGAGGGCGTGGCGGCCCCGCTG
  CAGTACCGCCACTCCGCGCAGCCCTGGGCCGACTTCACGCTGCTGGGCGCCCCGCGCCCC
  CGGCACCTACAGCTGCTACTATTCACACGCCCTCCGCGCCCTACGTGCTGTCGCAGCGCA
  CCGAGGTGCTGCCCATATCCTGGGAAGACTCTGCTTCTTCCGCTACCCCGGGGGAACCTA
  CTCGCCCGGGCTGCCCGGCTGGTCCTAATTTCCTGGGGCGCCGCAACTTTGACTGCGCAC
  CAGACGCGCTCTGCTGTATTCGCCCTGACCCAGGACACTGAACCGAGACTTCAACTGAGG
  GGGGAAAACTGGACCCGGCTGGATGGCTTTTCTGCACCCCCAGGCTGCTGGTTACTTCCG
  GGACGGGCCTTAAACCCGTGGCCCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_133168
• ORF Size: 759 bp
• Insert Size: 1500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_133168.2, NP_573398.1
• RefSeq Size: 1395
• RefSeq ORF: 759
• Locus ID: 126014
• Domains: IG
• Protein Families: Druggable Genome
• Gene Summary: Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
  Transcript Variant: This variant (5) lacks two in-frame exons in the central coding region and lacks an internal segment in its 3' coding region, compared to variant 1. The encoded isoform (5) is shorter and has a distinct C-terminus, compared to isoform 1.