Cystatin C (CST3) (NM_000099) Human Untagged Clone

CAT#: SC110862

CST3 (untagged)-Human cystatin C (CST3)


  "NM_000099" in other vectors (6)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

Product Images

Other products for "CST3"

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol CST3
Synonyms ARMD11; HEL-S-2
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC110862 sequence for NM_000099 edited (data generated by NextGen Sequencing)
ATGGCCGGGCCCCTGCGCGCCCCGCTGCTCCTGCTGGCCATCCTGGCCGTGGCCCTGGCC
GTGAGCCCCGCGGCCGGCTCCAGTCCCGGCAAGCCGCCGCGCCTGGTGGGAGGCCCCATG
GACGCCAGCGTGGAGGAGGAGGGTGTGCGGCGTGCACTGGACTTTGCCGTCGGCGAGTAC
AACAAAGCCAGCAACGACATGTACCACAGCCGCGCGCTGCAGGTGGTGCGCGCCCGCAAG
CAGATCGTAGCTGGGGTGAACTACTTCTTGGACGTGGAGCTGGGCCGAACCACGTGTACC
AAGACCCAGCCCAACTTGGACAACTGCCCCTTCCATGACCAGCCACATCTGAAAAGGAAA
GCATTCTGCTCTTTCCAGATCTACGCTGTGCCTTGGCAGGGCACAATGACCTTGTCGAAA
TCCACCTGTCAGGACGCCTAG

Clone variation with respect to NM_000099.2
>OriGene 5' read for NM_000099 unedited
GTATACGACTCCTATAGGCGGCCGCGACATTCGCACGAGGCTCGGTATCGCAGCGGGTCC
TCTCTATCTAGCTCCAGCCTCTCGCCTGCGCCCCACTCCCCGCGTCCCGCGTCCTAGCCG
ACCATGGCCGGGCCCCTGCGCGCCCCGCTGCTCCTGCTGGCCATCCTGGCCGTGGCCCTG
GCCGTGAGCCCCGCGGCCGGCTCCAGTCCCGGCAAGCCGCCGCGCCTGGTGGGAGGCCCC
ATGGACGCCAGCGTGGAGGAGGAGGGTGTGCGGCGTGCACTGGACTTTGCCGTCGGCGAG
TACAACAAAGCCAGCAACGACATGTACCACAGCCGCGCGCTGCAGGTGGTGCGCGCCCGC
AAGCAGATCGTAGCTGGGGTGAACTACTTCTTGGACGTGGAGCTGGGCCGAACCACGTGT
ACCAAGACCCAGCCCAACTTGGACAACTGCCCCTTCCATGACCAGCCACATCTGAAAAGG
AAAGCATTCTGCTCTTTCCAGATCTACGCTGTGCCTTGGCAGGGCACAATGACCTTGTCG
AAATCCACCTGTCAGGACGCCTAGGGGTCTGTACCGGGCTGGCCTGTGCCTATCCCTCTA
TCNCACACCCTCCCACCCCCTGTATTCCCACCCCTGGACTGGTGGCCCCCGGCCTGGGGG
AAGTTCTCCCCATTGTCCCTGCACCANGAGACAGACAGAGAAGGCAGCAGGCGGGNCCTT
TGNTGCTCAGCAGGGGGCTCTGCCCTCCCTCCTTCCTTTCTTGCTCTCATAGCCCCGGGG
TGCGGTGCATACACCCCCCACCTCCTGCATAAAATAGTAGCATCGGCAAAAAAAAAAAAA
AACTCACTCTAAATTGCGGCCGCGGTCATAACTGTTTCTGAAAAAACCCGGTGGGGATCC
TGGGGACCCTCCCAAGCCTTTCTGGCCTGGGAAGGCCATTCCAGGCCCCCACCTGGCTAA
AAAAAAAGCAATTTGCGACAGGGCTTATATGGGGGGGGGGGGGGGGGGGGNGGACACAAC
CACACA
>OriGene 3' read for NM_000099 unedited
AGCTATGGACCCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGCCGATGC
TACTATTTTATTGCAGGAGGTGGGGGTGTATGCACCGCACACCGGGGCTATGAGAAGCAA
GAAGGAAGGAGGGAGGGCAGAGCCCCTTGCTGAGCAACAAAGGCCGCCTGCTGCCTTCTC
TGTCTGTCTCCTGGTGCAGGCACATGGGGAGACCTTCCCCAAGGCAGGGGCCACCAGTCC
AGGGGTGGGAATACAGGGGGTGGGAGGTGTGCATAAGAGGTGATAGGCACAGGCCAGCCC
GGTACAGACCCCTAGGCGTCCTGACAGGTGGATTTCGACAAGGTCATTGTGCCCTGCCAA
GGCACAGCGTAGATCTGGAAAGAGCAGAATGCTTTCCTTTTCAGATGTGGCTGGTCATGG
AAGGGGCAGTTGTCCAAGTTGGGCTGGGTCTTGGTACACGTGGTTCGGCCCAGCTCCACG
TCCAAGAAGTAGTTCACCCCAGCTACGATCTGCTTGCGGGCGCGCACCACCTGCAGCGCG
CGGCTGTGGTACATGTCGTTGCTGGCTTTGTTGTACTCGCCGACGGCAAAGTCCAGTGCA
CGCCGCACACCCTCCTCCTCCACGCTGGCGTCCATGGGGCCTCCCACCAGGCGCGGCGGC
TTGCCGGGACTGGAGCCGGCCGCGGNGCTCACGGNCCAGGCCACGGCCAGGATGGCCCAG
CAGAGCCAGCGGGCGCGCAGGGGCCCGGCCATGGTCGGCTAGGACGCCGGACCCNGNGAG
TGGGGCCCAAGCGAAAGCCTGAANCTANATANAGAGGACCCGCTGCGATACGGAGCCTCG
TGCCGAATTCCGGNCCGCCCTAAGTGAGTCGTATACAAAATCTGACGNTCACTAACGAGC
TCTGCTATATAGACCTCCCACGTCACGCCTAN
Restriction Sites NotI-NotI     
ACCN NM_000099
Insert Size 820 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_000099.2, NP_000090.1
RefSeq Size 818 bp
RefSeq ORF 441 bp
Locus ID 1471
Cytogenetics 20p11.21
Domains CY
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Gene Summary 'The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus. Alternative splicing results in multiple transcript variants encoding a single protein. [provided by RefSeq, Nov 2014]'
Transcript Variant: This variant (1) differs in the 3' UTR compared to variant 2. Variants 1 and 2 encode the same protein.

Other Versions

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.