MAG (NM_002361) Human Untagged Clone

CAT#: SC110943

MAG (untagged)-Human myelin associated glycoprotein (MAG), transcript variant 1


  "NM_002361" in other vectors (6)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

Product Images

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol MAG
Synonyms GMA; S-MAG; SIGLEC-4A; SIGLEC4A; SPG75
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC110943 sequence for NM_002361 edited (data generated by NextGen Sequencing)
ATGATATTCCTCACGGCACTGCCTCTGTTCTGGATTATGATTTCAGCCTCCCGAGGGGGT
CACTGGGGTGCCTGGATGCCCTCGTCCATCTCGGCCTTCGAAGGCACGTGCGTCTCCATC
CCCTGCCGCTTTGACTTCCCGGATGAGCTGCGGCCCGCTGTGGTGCATGGTGTCTGGTAC
TTCAATAGCCCCTACCCCAAGAACTACCCCCCGGTGGTCTTCAAGTCGCGCACCCAAGTA
GTCCACGAGAGCTTCCAGGGCCGCAGCCGCCTCCTGGGGGACCTGGGCCTGCGAAACTGC
ACCCTCCTGCTCAGCAACGTCAGCCCCGAGCTGGGCGGGAAGTACTACTTCCGTGGGGAC
CTGGGCGGCTACAACCAGTACACCTTCTCAGAGCACAGTGTCCTGGATATCGTCAACACC
CCCAACATCGTGGTGCCCCCAGAGGTGGTGGCAGGCACGGAGGTGGAGGTCAGCTGCATG
GTGCCGGACAACTGCCCAGAGCTGCGCCCTGAGCTGAGCTGGCTGGGCCACGAGGGGCTG
GGGGAGCCCGCTGTGCTGGGCCGGCTGCGGGAGGACGAGGGCACCTGGGTGCAGGTGTCA
CTGCTGCACTTCGTGCCCACGAGGGAGGCCAACGGCCACAGGCTGGGCTGCCAGGCCTCC
TTCCCCAACACCACCCTGCAGTTCGAGGGCTACGCCAGCATGGACGTCAAGTACCCCCCG
GTGATTGTGGAGATGAACTCCTCGGTGGAGGCCATCGAGGGCTCCCACGTGAGCCTGCTC
TGTGGGGCTGACAGCAACCCCCCGCCGCTGCTGACCTGGATGCGGGACGGGACAGTCCTC
CGGGAGGCGGTGGCCGAGAGCCTGCTCCTGGAGCTGGAGGAGGTGACCCCCGCCGAAGAC
GGCGTCTATGCCTGCCTGGCCGAGAATGCCTATGGCCAGGACAACCGCACCGTGGGGCTC
AGTGTCATGTATGCACCCTGGAAGCCAACAGTGAACGGGACAATGGTGGCCGTAGAGGGG
GAGACGGTCTCTATCTTGTGCTCCACACAGAGCAACCCGGACCCTATTCTCACCATCTTC
AAGGAGAAGCAGATCCTGTCCACGGTCATCTACGAGAGCGAGCTGCAGCTGGAGCTGCCG
GCCGTGTCACCCGAGGATGATGGAGAGTACTGGTGTGTGGCTGAGAACCAGTATGGCCAG
AGGGCCACCGCCTTCAACCTGTCTGTGGAGTTCGCCCCTGTGCTCCTCCTGGAGTCCCAC
TGCGCGGCAGCCCGAGACACGGTGCAGTGCCTGTGCGTGGTGAAGTCCAACCCGGAGCCG
TCCGTGGCCTTTGAGCTGCCATCGCGCAATGTGACCGTGAACGAGAGCGAGCGGGAGTTC
GTGTACTCGGAGCGCAGCGGCCTCGTGCTCACCAGCATCCTCACGCTGCGGGGGCAGGCC
CAGGCCCCGCCCCGCGTCATCTGCACCGCGAGGAACCTCTATGGCGCCAAGAGCCTGGAG
CTGCCCTTCCAGGGAGCCCATCGACTGATGTGGGCCAAGATCGGGCCTGTGGGCGCCGTG
GTCGCCTTTGCCATCCTGATTGCCATCGTCTGCTACATTACCCAGACACGCAGGAAAAAG
AACGTGACAGAGAGCCCCAGCTTCTCGGCAGGGGACAACCCTCCCGTCCTGTTCAGCAGC
GACTTCCGCATCTCTGGGGCACCAGAGAAGTACGAGAGCGAGAGGCGCCTGGGATCTGAG
AGGAGGCTGCTGGGCCTTCGGGGTGAGCCCCCAGAGCTGGACCTGAGCTATTCTCACTCG
GACCTGGGGAAACGGCCCACCAAGGACAGCTACACGCTGACGGAGGAGCTAGCTGAGTAT
GCTGAAATCCGGGTCAAGTGA

Clone variation with respect to NM_002361.3
399 c=>t
>OriGene 5' read for NM_002361 unedited
GCAAACCCATTCGGCACGAGGCGGAGCAGATGTGCAGAAGCAACTGAGTCCAAGTTGTCT
GGCGGCTTCAGGTGGACCCAGAAGACGTCCCCAACTCAGGGAGATTCAGCGATCACTCAC
TCGCTGTACAGAATGATATTCCTCACGGCACTGCCTCTGTTCTGGATTATGATTTCAGCT
CCCTCGTTGGGGTCACTGGGGTGCCTGGATGCCCTCGTCCATCTCGGCCTTCGAAGGCAC
GTGCGTCTCCATCCCCTGCCGCTTTGACTTCCCGGATGAGCTGCGGCCCGCTGTGGTGCA
TGGTGTCTGGTACTTCAATAGCCCCTACCCCAAGAACTACCCCCCGGTGGTCTTCAAGTC
GCGCACCCAAGTAGTCCACGAGAGCTTCCAGGGCCGCAGCCGCCTCCTGGGGGACCTGGG
CCTGCGAAACTGCACCCTCCTGCTCAGCAACGTCAGCCCCGAGCTGGGCGGGAAGTACTA
CTTCCGTGGGGACCTGGGCGGCTACAACCAGTACACCTTCTCAGAGCACAGTGTCCTGGA
TATCGTCAACACCCCCAACATCGTGGTGCCCCCAGAGGTGGTGGCAGGCACGGAGGTGGA
GGTCAGCTGCATGGTGCCGGACAACTGCCCAGAGCTGCGCCCTGAGCTGAGCTGGCTGGG
CCACGANGGGCTGGGGGAGCCCGCTGTGCTGGGCCCGCTGCGGGAGGACGAGGGCACCTG
GGTGCANGTGTCACTGCTGCACTTCGTGCCCACGAGGGAGGCCAACCGCCACAGGCTGGG
CTGCCAGGCCTCCTTTCCNCACACCACCCTGCAGTTCGAAGGCTACGCCAGCATGGACGT
TCAGTACCCCCGGGTGATTGGGGAGATGAACTCCTCGTTGAGGCC
>OriGene 3' read for NM_002361 unedited
ATGGACCGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGGCTTTGGGGCA
TTTATTTCATGTCCCTTTTGTACAGGCCCCAGGGCCAGGTGTGGGGGCAGGAGACCAGGC
AGGAAGTAGCAATAAATAACACGGACAGACAGAGCTCCCCTCCAGACAGATGAGGGTAAA
GGAGGTTAGAGAGGAGCCGTAATGAGGGCGTGGGGGTGCTGGCAGGGAGGGGCAGCTGGG
AAGGAGGGGGAGGTCAGGCCCCCAGGACCTCACTGTCACCTGCCTCACTCCCCTCCTGCC
CCAGCCCCCGATACTTTTGGGAGGAAGGGAGCCCACAGCCAGTGGGGGCCAGCGAGGGTC
CTGAGGGGGGTATTTTTACCATTTCTCACCTTTTATTTCCCACCCCACCCCCTTCCCCCC
CCCCCCTTCCTCCCTTTCCCCTCTCTTCGCCTCCCACCCCCCTCCCCCCCTTCCCCCCTT
TTCCACCTATTTATTTTCTCAACCTCACTCACCTAGCCTCAGCCTCAGCTATTCACCCTG
CGCAACCCTCCCTCCCCCCCCCCTCCCCCTATACCTCCTACTTTCTTTTATTTCCATCCC
CCCCCCTCCCCCTCTCTCGCTTCCCCCCCCACAATAATTTATCAATTCACACTCGTCTGT
GACCTTCCGCCGCACCCACCGCGAATAATATCCCCCCCCTCCCTCCCGCCTCCCGCCCCC
ATCTTTATTATTATTCTCCCCCCCCTTTTCTCTGCATCACCCCACCCCTCCCATTTCTTC
TCTTTATAAAGAAGTACCCTCTCCCCCCGCCGCCTCGCGATTACATTCTTTCTCCTCTCT
CTCCCCCTCTGCACCTCTCTCATCATTAGCATCTCACTTCTTCTCTTCTCTTCGCTCGCG
TACACCCCGAGATTTTATTCCGGCGTTCCATTTCGCCTCGCTCGCTN
Restriction Sites NotI-NotI     
ACCN NM_002361
Insert Size 2440 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_002361.2, NP_002352.1
RefSeq Size 2380 bp
RefSeq ORF 1881 bp
Locus ID 4099
Cytogenetics 19q13.12
Domains ig, IGc2, IG
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs)
Gene Summary 'The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2010]'
Transcript Variant: This variant (1) lacks exon 11 and has the stop codon in exon 12, as compared to variant 2. Isoform a is 44 aa longer and contains a different carboxy terminus when compared to isoform b.

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