Syndecan 2 (SDC2) (NM_002998) Human Untagged Clone

CAT#: SC111011

SDC2 (untagged)-Human syndecan 2 (SDC2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SDC2
• Synonyms: CD362; HSPG; HSPG1; SYND2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC111011 sequence for NM_002998 edited (data generated by NextGen Sequencing)
  ATGCGGCGCGCGTGGATCCTGCTCACCTTGGGCTTGGTGGCCTGCGTGTCGGCGGAGTCG
  AGAGCAGAGCTGACATCTGATAAAGACATGTACCTTGACAACAGCTCCATTGAAGAAGCT
  TCAGGAGTGTATCCTATTGATGACGATGACTACGCTTCTGCGTCTGGCTCGGGAGCTGAT
  GAGGATGTAGAGAGTCCAGAGCTGACAACATCTCGACCACTTCCAAAGATACTGTTGACT
  AGTGCTGCTCCAAAAGTGGAAACCACGACGCTGAATATACAGAACAAGATACCTGCTCAG
  ACAAAGTCACCTGAAGAAACTGATAAAGAGAAAGTTCACCTCTCTGACTCAGAAAGGAAA
  ATGGACCCAGCCGAAGAGGATACAAATGTGTATACTGAGAAACACTCAGACAGTCTGTTT
  AAACGGACAGAAGTCCTAGCAGCTGTCATTGCTGGTGGAGTTATTGGCTTTCTCTTTGCA
  ATTTTTCTTATCCTGCTGTTGGTGTATCGCATGAGAAAGAAGGATGAAGGAAGCTATGAC
  CTTGGAGAACGCAAACCATCCAGTGCTGCTTATCAGAAGGCACCTACTAAGGAGTTTTAT
  GCGTAA
  
  Clone variation with respect to NM_002998.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002998 unedited
  GTTAGAAATTATGTAATACGACTCACTATAGGGCGGCCGCGAATCGGCACGAGCAGCCGC
  GGAGCCAGTGGCCCCGCTTGGACGCGCTGCTCTCCAGATACCCCCGGAGCTCCAGCCGCG
  CGGATCGCGCGCTCCCGCCGCTCTGCCCCTAAACTTCTGCCGTAGCTCCCTTTCAAGCCA
  GCGAATTTATTCCTTAAAACCAGAAACTGAACCTCGGCACGGGAAAGGAGTCCGCGGAGG
  AGCAAAACCACAGCAGAGCAAGAAGAGCTTCAGAGAGCAGCCTTCCCGGAGCACCAACTC
  CGTGTCGGGAGTGCAGAAACCAACAAGTGAGAGGGCGCCGCGTTCCCGGGGCGCAGCTGC
  GGGCGGCGGGAGCAGGCGCAGGAGGAGGAAGCGAGCGCCCCCGAGCCCCGAGCCCGAGTC
  CCCGAGCCTGAGCCGCAATCGCTGCGGTACTCTGCTCCGGATTCGTGTGCGCGGGCTGCG
  CCGAGCGCTGGGCAGGAGGCTTCGTTTTGCCCTGGTTGCAAGCAGCGGCTGGGAGCAGCC
  GGTCCCTGGGGAATATGCGGCGCGCGTGGATCCTGCTCACCTTGGGCTTGGTGGCCTGCG
  TGTCGGCGGAGTCGAGAGCAGAGCTGACATCTGATAAAGACATGTACCTTGACAACAGCT
  CCATTGAAGAAGCTTCAGGAGTGTATCCTATTGATGACGATGACTACGCTTCTGCGTCTG
  GCTCGGGAGCTGATGAGGATGTAGAGAGTCCAGAGCTGACAACATCTCGACCACTTCCAA
  AGATACTGTTGACTAGTGCTGCTCCAAAGTGGAAACCACGACGCTGAATATACAGAACAA
  GATACCTGCTCAGACAAAGTCACCTGAAGAAACTGATNAAGAGAAANGTCACCTCTCTGA
  CTCAGAAGGNAAANTGGACCAGNCGCAGAGATACAAAGTGTATACTGAGAAACCTCA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002998 unedited
  NNTTTTTGCTCTGGACCCGCGGCCGCATNCTAGNGATCGGTTTTTTTTTTTTTTTTTTAG
  GCCACATGATTTATTCAGTAGTTTTTATGTTCCCAAATACAATTTATGTCTATTCATAAG
  ACTACAAAAGTTACCATTAGAATTGTCTGTGCTTATAAAATACCAACTTTTTTTTTAAAC
  TGTTACATATACTCATTAACACCAGTCTGCAACAAGTTACATAGAATCAGAGGCACTTCA
  AAGGCTTAAAAAGACGTTTACAACTTAAATGCATTTTTAAGAACAAAAACTGATTTTTCT
  TTAAACCTCTACTCGTACCTTCAAATTGCAAGAAATTAACAAATACAGTGGCCAAAGGAA
  TCTGCAGCAACTTCTTAAAATACTGTTAACATCTTTGGGTTTGCTGAGGCTTGTCAGTAA
  CTTACATCAAATCCTCCCAAAAGAAGATCTGATTAGATAGATATGACTAAACGGTTTTGT
  AGTAATAATCCAATTTTACACATTAATTTGCTGTTGCAAATCTGCCCAAAGCTACAGGTA
  ATGAAAAATAAAGCAAGTGTAAAATGGATAGTCTGACACTTAAAAATTTATACAAAGCGG
  AAGTTAAAGTTTACATATTTTGAAAATCACATATCCCCTAAATTACCCTTATCTGAATTT
  TCCCAAAGACAAATTGCCCCATGACAGCCTACAAAAAGCATATGGCTTTGGCTTTAAGGG
  CCCCCTCAAGGTAGGGCATAACGATAGGAAGGGCACCTCGCATATCTTACCAAAGTCTGA
  CCACCTTGTTCAGGTCATTCTGACACATGCTGACACAAAGGAAACACTTTTTCTCTTTGA
  TCTCTAGGAAAACGAAACTTTTTGGTCTTTGCCTCTACACTCCAACCCCTCCCTGTACCC
  ACTAGTTTCCACACCAATAACTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002998
• Insert Size: 2210 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002998.3, NP_002989.2
• RefSeq Size: 3485 bp
• RefSeq ORF: 606 bp
• Locus ID: 6383
• Cytogenetics: 8q22.1
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), ECM-receptor interaction
• Gene Summary: 'The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008]'