SCO2 (NM_005138) Human Untagged Clone

CAT#: SC111130

SCO2 (untagged)-Human SCO cytochrome oxidase deficient homolog 2 (yeast) (SCO2), nuclear gene encoding mitochondrial protein, transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SCO2
• Synonyms: CEMCOX1; ECGF1; Gliostatin; MYP6; PD-ECGF; SCO1L; TdRPase; TP; TYMP
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC111130 sequence for NM_005138 edited (data generated by NextGen Sequencing)
  ATGCTGCTGCTGACTCGGAGCCCCACAGCTTGGCACAGGCTCTCTCAGCTCAAGCCTCCG
  GTCCTCCCTGGGACCCTGGGAGGCCAGGCCCTGCATCTGAGGTCCTGGCTTTTGTCAAGG
  CAGGGCCCTGCAGAGACAGGTGGGCAGGGCCAGCCCCAGGGCCCTGGGCTTCGAACCCGG
  CTGCTGATCACAGGCCTGTTCGGGGCTGGACTCGGTGGGGCCTGGCTGGCCCTGAGGGCT
  GAGAAGGAGAGGCTGCAGCAGCAAAAGCGAACAGAAGCCCTGCGCCAGGCAGCTGTGGGC
  CAGGGCGACTTCCACCTGCTGGATCACAGAGGCCGGGCTCGCTGCAAGGCTGACTTCCGG
  GGCCAGTGGGTGCTGATGTACTTTGGCTTCACTCACTGCCCTGACATCTGCCCAGACGAG
  CTGGAGAAGCTGGTGCAGGTGGTGCGGCAGCTGGAAGCAGAGCCTGGTTTGCCTCCAGTG
  CAGCCTGTCTTCATCACTGTGGACCCCGAGCGGGACGACGTTGAAGCCATGGCCCGCTAC
  GTCCAGGACTTCCACCCAAGACTGTTGGGTCTGACCGGCTCCACCAAACAGGTTGCCCAG
  GCTAGTCACAGTTACCGCGTGTACTACAATGCCGGCCCCAAGGATGAGGACCAGGACTAC
  ATCGTGGACCACTCCATTGCCATCTACCTGCTCAACCCTGACGGCCTCTTCACGGATTAC
  TACGGCCGGAGCAGATCGGCTGAGCAGATCTCAGACAGTGTGCGGCGGCACATGGCGGCT
  TTCCGCAGTGTCCTGTCTTGA
  
  Clone variation with respect to NM_005138.2
  59 g=>c;633 a=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005138 unedited
  CAGAATTTTGTAATACGACTCACTATAGGGCGGCCCGCGATTCGGCACGAGGCAAATAGA
  TAACGTGGTTAGTTCAGGCAAGGCATGCACTTGGAATGCTTTCCGTCAGCAAGAGGTTCA
  CCTTGCTGAGGTGCAGGTGCAGGTGCAGGGCAGGGTGCGGTGACAGGCTGGTGATCCCAG
  GTAGAGGACAGGAGTGACAGGTGTGGTTGCCCAGGTGTGGATGTTTGGTGGAGGTGGAGT
  TCTGAGCTCAGGTGAGCAGCTGCAAATGCCTGTTAAGCCTGAACGTGGGCTGGGTACTTC
  AGATGGGTGGCTGGTCTCAAGTCGCAGGGGCAGCCCAGGCACTGTCCTGGGCCTTCCCTT
  CTGGCTCCTGACGCCTGTGCTTGTTTCCAGGAGCATCAGATCCATGCTGCTGCTGACTCG
  GAGCCCCACAGCTTGGCACAGGCTCTCTCAGCTCAAGCCTCCGGTCCTCCCTGGGACCCT
  GGGAGGCCAGGCCCTGCATCTGAGGTCCTGGCTTTTGTCAAGGCAGGGCCCTGCAGAGAC
  AGGTGGGCAGGGCCAGCCCCAGGGCCCTGGGCTTCGAACCCGGCTGCTGATCACAGGCCT
  GTTCGGGGCTGGACTCGGTGGGGCCTGGCTGGCCCTGAGGGCTGAGAAGGAGAGGCTGCA
  GCAGCAAAAGCGAACAGAAGCCCTGCGCCAGGCAGCTGTGGGCCAGGGCGACTTCCACCT
  GCTGGNATCACAGAGCCGGGCTCGCTGCAAGGCTGACTTCCGGGGCCAGTGGGTGCTGAT
  GTACTTTGGCTNACTCACTGCCCTGACATCTGCCCAAACGAGCTGNANAANNCTGTGCAN
  GTGGTGCCGCANCTGAANCANAGCCTGTNTNGCCTCCAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005138 unedited
  CCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAAACGCAGCCCGTTTAAT
  GATGGGGCCCAGACTGCAGTGGCTCAAGACAGGACACTGCGGAAAGCCGCCATGTGCCGC
  CGCACACTGTCTGAGATCTGCTCAGCCGATCTGCTCCGGCCGTAGTAATCCGTGAAGAGG
  CCGTCAGGGTTGAGCAGGTAGATGGCAATGGAGTGGTCCACGATGTAGTCCTGGTCCTCA
  TCCTTGGGGCCGGCATTGTAGTACACGCGGTAACTGTGACTAGCCTGGGCAACCTGTTTG
  GTGGAGCCGGTCAGACCCAACAGTCTTGGGTGGAAGTCCTGGACGTACCGGGCCATGGCT
  TCAACGTCGTCCCGCTCGGGGTCCACAGTGATGAACACAGGCTGCACTTGGAGCAAACCA
  GGCTCTGCTTCCAGCTGCCGCACCACCTGCACCACTTTTTCCACCTTGCTCTGGCCATAT
  GTTAGGGGCACTGATGCGACCCTAAGTTCATTCTTCCTCCCCTGATTTCCGGAATTACCT
  CCTCTTTCACCCCGATCCTTTGCTATCTAATTCCCGCAACCAATAATTCCTCTCTACGCC
  CCGGATATCGCCCCATTCCCCTTTTCCTTGTCCACATCTTCTCCTCCCCCGCTCTTTTCC
  CCCTCCATTTCCCTCTCCCCGTATTTCTGTTCCCCCCCCGTTTCGCTCCGGCCTTCCTAG
  TATACACCCCCTTCTCTCTTCACCTCTCTCCGCCCTCTCGCCCGTCCCCCAACTCTCCCT
  TACCCACCCATCCCTCCCCTCCTTCCATTCCACCCCCCCCTCCTCCCCCCTTTCCGTCAT
  CTCCCTCCTTCTCTCTCCTCCCCCTCTTTCTTCCCCCGCCCCACCCTATTCCCGACTTCC
  CTCCGTCNTATCTCCATCCCTTCTCTCCCCATGTTATTATTTCTCCGACTCCCCTATCTC
  ATTCTCCCTGACCTCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005138
• ORF Size: 801 bp
• Insert Size: 1310
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_005138.1, NP_005129.1
• RefSeq Size: 931
• RefSeq ORF: 801
• Locus ID: 9997
• Domains: SCO1-SenC
• Protein Families: Druggable Genome
• Gene Summary: Cytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors; this gene encodes one of the COX assembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in this gene are associated with fatal infantile encephalocardiomyopathy and myopia 6. [provided by RefSeq, Oct 2014]
  Transcript Variant: This variant (1) represents the shortest transcript. Variants 1, 2, 3 and 4 encode the same protein.