SA2 (STAG2) (NM_006603) Human Untagged Clone

CAT#: SC111166

STAG2 (untagged)-Human stromal antigen 2 (STAG2), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: STAG2
• Synonyms: bA517O1.1; NEDXCF; SA-2; SA2; SCC3B
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC111166 sequence for NM_006603 edited (data generated by NextGen Sequencing)
  ATGATAGCAGCTCCAGAAATACCAACTGATTTTAATCTACTACAGGAGTCAGAAACACAT
  TTTTCTTCTGACACAGATTTTGAAGATATCGAAGGAAAAAACCAAAAGCAAGGCAAAGGC
  AAAACTTGTAAAAAAGGCAAAAAGGGCCCAGCAGAAAAGGGCAAAGGTGGAAATGGAGGA
  GGAAAACCTCCTTCTGGTCCAAACCGAATGAATGGTCATCACCAACAGAATGGAGTGGAA
  AACATGATGTTGTTTGAAGTTGTTAAAATGGGCAAGAGTGCTATGCAGTCGGTGGTAGAT
  GATTGGATAGAATCATACAAGCATGACCGAGATATAGCACTTCTTGACCTTATCAACTTT
  TTTATTCAGTGTTCAGGCTGTAAAGGAGTTGTCACAGCAGAAATGTTTAGACATATGCAG
  AACTCTGAGATAATTCGAAAAATGACTGAAGAATTCGATGAGGATAGTGGAGATTATCCA
  CTTACCATGGCTGGTCCTCAGTGGAAGAAGTTCAAATCCAGTTTTTGTGAATTCATTGGC
  GTGTTAGTACGGCAATGTCAATATAGTATCATATATGATGAGTATATGATGGATACAGTC
  ATTTCACTTCTTACAGGATTGTCTGACTCACAAGTCAGAGCATTTCGACATACAAGCACC
  CTGGCAGCTATGAAGTTGATGACAGCTTTGGTGAATGTGGCACTAAATCTTAGCATTAAT
  ATGGATAATACACAAAGACAATATGAAGCAGAACGGAATAAAATGATTGGAAAACGAGCC
  AATGAGAGGCTAGAACTCCTGCTACAAAAGCGGAAAGAGCTTCAGGAAAATCAAGATGAA
  ATAGAAAATATGATGAATGCAATATTTAAAGGAGTGTTTGTACATAGATACCGTGATGCG
  ATAGCTGAAATTCGAGCTATTTGCATTGAAGAGATTGGCATTTGGATGAAGATGTATAGT
  GATGCCTTTCTTAATGACAGTTATTTAAAATATGTTGGTTGGACTATGCATGATAAGCAA
  GGTGAAGTAAGACTCAAATGTCTTACTGCTCTACAAGGGCTTTATTATAACAAAGAGCTT
  AATTCCAAACTGGAACTTTTTACCAGTCGGTTCAAGGATAGAATTGTGTCTATGACCCTT
  GACAAAGAATATGATGTTGCAGTACAAGCAATAAAATTACTCACTCTTGTTTTACAGAGT
  AGTGAAGAAGTTCTCACTGCAGAAGATTGTGAAAATGTCTATCATCTGGTTTATTCAGCT
  CACCGGCCAGTAGCAGTAGCAGCTGGAGAATTTCTCTACAAAAAGCTCTTCAGTCGTAGA
  GATCCAGAGGAGGATGGAATGATGAAAAGAAGAGGAAGACAAGGTCCAAATGCCAACCTT
  GTTAAGACATTGGTTTTTTTCTTTCTAGAAAGTGAGTTACATGAGCATGCAGCATACCTT
  GTGGATAGCATGTGGGACTGTGCTACTGAGCTGCTGAAAGACTGGGAATGTATGAATAGC
  TTGTTACTGGAAGAGCCACTTAGTGGAGAGGAAGCACTAACAGATAGGCAAGAGAGTGCT
  CTGATTGAAATAATGCTTTGTACCATTAGACAAGCGGCTGAATGTCATCCTCCCGTGGGA
  AGAGGGACAGGAAAAAGGGTGCTTACAGCAAAGGAGAAGAAGACACAGTTGGATGATAGG
  ACAAAAATCACTGAGCTTTTTGCCGTGGCCCTTCCTCAGTTATTAGCAAAATACTCTGTA
  GATGCAGAAAAGGTGACTAACTTGTTGCAGTTGCCTCAGTACTTTGATTTGGAAATATAT
  ACCACTGGACGATTAGAAAAGCATTTGGATGCCTTATTGCGACAGATCCGGAATATTGTA
  GAGAAGCACACAGATACAGATGTTTTGGAAGCATGTTCTAAAACTTACCATGCACTCTGT
  AATGAAGAGTTCACAATCTTCAACAGAGTAGATATTTCAAGAAGTCAACTGATAGATGAA
  TTGGCAGATAAATTTAACCGGCTTCTTGAAGATTTTCTGCAAGAGGGTGAAGAACCTGAT
  GAAGATGATGCATATCAGGTATTGTCAACATTGAAGAGGATCACTGCTTTTCATAATGCC
  CATGACCTTTCAAAGTGGGATTTATTTGCTTGTAATTACAAACTCTTGAAAACTGGAATC
  GAAAATGGAGACATGCCTGAGCAGATTGTTATTCACGCACTGCAGTGTACTCACTATGTA
  ATCCTTTGGCAACTTGCTAAGATAACTGAAAGCAGCTCTACAAAGGAGGACTTGCTGCGT
  TTAAAGAAACAAATGAGAGTATTTTGTCAGATATGTCAACATTACCTGACCAACGTGAAT
  ACTACTGTTAAGGAACAGGCCTTCACTATTCTGTGTGATATTTTGATGATCTTCAGCCAT
  CAGATTATGTCAGGAGGGCGTGACATGTTAGAGCCATTAGTGTATACCCCTGATTCTTCA
  TTGCAGTCTGAGTTGCTCAGCTTTATTTTGGATCATGTCTTCATTGAACAGGATGATGAT
  AATAATAGTGCAGATGGTCAGCAAGAGGATGAAGCCAGTAAAATTGAAGCTCTGCACAAG
  AGAAGAAATTTACTTGCAGCATTTTGTAAGCTAATTGTATATACTGTGGTGGAGATGAAT
  ACAGCTGCAGATATCTTCAAACAGTATATGAAGTATTATAATGACTATGGAGATATCATC
  AAAGAAACAATGAGTAAAACAAGGCAGATAGACAAAATTCAGTGTGCTAAGACCCTTATT
  CTCAGTCTGCAACAGCTTTTTAATGAAATGATACAAGAAAATGGCTATAATTTTGATAGA
  TCATCCTCTACATTTAGTGGCATAAAAGAACTTGCTCGACGTTTTGCTTTAACTTTTGGA
  CTTGATCAGTTGAAAACAAGAGAAGCCATTGCCATGCTACACAAAGATGGCATAGAATTT
  GCTTTTAAAGAGCCTAATCCGCAAGGGGAGAGCCATCCACCTTTAAATTTGGCATTTCTT
  GATATTCTGAGTGAATTTTCTTCTAAACTACTTCGACAAGACAAAAGAACAGTGTATGTT
  TACTTGGAAAAGTTCATGACCTTTCAGATGTCACTCCGAAGAGAGGATGTGTGGCTTCCA
  CTGATGTCTTACCGAAATTCTTTGCTAGCTGGTGGTGATGATGACACCATGTCAGTCATT
  AGTGGAATCAGCAGCCGGGGGTCAACAGTACGGAGTAAAAAATCAAAACCATCTACAGGA
  AAACGGAAAGTGGTTGAGGGCATGCAGCTTTCACTCACTGAAGAAAGTAGTAGTAGTGAC
  AGTATGTGGTTAAGCAGAGAACAAACACTGCACACCCCTGTTATGATGCAGACACCACAA
  CTCACCTCCACTATTATGAGAGAGCCCAAAAGATTACGGCCTGAGGATAGCTTCATGAGT
  GTTTATCCAATGCAGACTGAACATCATCAAACACCTCTTGATTATAATCGGCGTGGCACA
  AGCCTAATGGAAGATGATGAAGAGCCAATTGTGGAAGATGTTATGATGTCCTCAGAAGGG
  AGGATTGAGGATCTTAATGAGGGAATGGATTTTGACACCATGGATATAGATTTGCCACCA
  TCAAAGAACAGACGAGAGAGAACAGAACTGAAGCCTGATTTCTTTGATCCAGCTTCAATT
  ATGGATGAATCAGTTCTTGGAGTGTCAATGTTTTAA
  
  Clone variation with respect to NM_006603.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006603 unedited
  GATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCCCCCCGCCC
  CATCATCTCCAGCGCGTGGTGGGGGAACTGCTGGGGAAGGCGATTGGCATCGATCTCTCC
  ATCCCTTCCGAGGCCCGACTTCGGAATTGTCTTAGAAGAAAGAAGGCAAGCCACCATTTT
  ACCCACGTAAATATATGAATATATTTCTGACATTGAGGTGTTCCAGAAGATGATAAAGAA
  ATGATAGCAGCTCCAGAAATACCAACTGATTTTAATCTACTACAGGAGTCAGAAACACAT
  TTTTCTTCTGACACAGATTTTGAAGATATCGAAGGAAAAAACCAAAAGCAAGGCAAAGGC
  AAAACTTGTAAAAAAGGCAAAAAGGGCCCAGCAGAAAAGGGCAAAGGTGGAAATGGAGGA
  GGAAAACCTCCTTCTGGTCCAAACCGAATGAATGGTCATCACCAACAGAATGGAGTGGAA
  AACATGATGTTGTTTGAAGTTGTTAAAATGGGCAAGAGTGCTATGCAGTCGGTGGTAGAT
  GATTGGATAGAATCATACAAGCATGACCGAGATATAGCACTTCTTGACCTTATCAACTTT
  TTTATTCAGTGTTCAGGCTGTAAAGGAGTTGTCACAGCAGAAATGTTTAGACATATGCAG
  AACTCTGAGATAATTCGAAAAATGACTGAAGAATTCGATGAGGATAGTGGAGATTATCCA
  CTTACCATGGCTGGTCCTCAGTGGAAGAAGTTCANATCCAGTTNTTGTGAATTCATTGGC
  GTGTTAGTACGGCAATGTCAATATAGTATCATATATGATGAGTATATGATGGATACAGTC
  ATTTCACTTCTTACAGGNATGTCTGACTCCCAAGTCAGAGCATTTCGACTACAAGCCCCT
  GCAGCTATGAAGTGATGACAGCTTGGTGAATGTGCACTAATCTTACATATATGATATACC
  AAGACATTGAGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006603 unedited
  AGCTTGGACCGGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTAAAAAAGCTG
  AAATAATCGATTCAAAAGCCAACTAACAGCGCATAAATAAAATATTTACTTTCTAAGAAA
  AACTGTAGCTTATCATCAAATTGTTTACTTGTCCTTTACGTTTATTCAGGCAAACAAAAC
  TGCCCCTCAATGCACTTGATCTTGGTAAGCATAAGCATGTCATATTCTCCTTAGAGAAAA
  ATCTGTACAGAATTTCACTGTATCTACCACACTTTAAAATTTCCTCTTCCACTTAGAAAA
  TGACTTCACCACAGATTTAATTGTGTACTGGTATTAAAACATTGACACTCCAAGAACTGA
  TTCATCCATAATTGAAGCTGGATCAAAGAAATCAGGCTTCAGTTCTGTTCTCTCTCGTCT
  GTTCTTTGATGGTGGCAAATCTATATCCATGGTGTCAAAATCCATTCCCTCATTAAGATC
  CTCAATCCTCCCTTCTGAGGACATCATAACATCTTCCACAATTGGCTCTTCATCATCTTC
  CATTAGGCTTGTGCCACGCCGAATGGCATGCTGAAGATTAGTTCGCAGTTTAACATAGCT
  CATTGCTGCTCTCTCCTGCTGNTGCCTTGCTTCCTCTTGTTGNNCTTGAGCTAACATCCA
  TGTTACCTGCGTNGTATAATCAAGAAGGTGTTGATGATGNTCAGTCTGCATTGGATAAAC
  ACTCATGAAGCTATCCTCAGGCCCGTATCTTTTGGGCTCTCTCATAATAGTGGNAGTGAG
  TTGTGGTGTCTGCATCATAACAGGGGTGTGCAGTGTTTGTTCTCTGCTTACCACATACTG
  TCACTACTACTACTTTNCTCAGNGAGTGAAAGCTGCATGCCCTCAACACTTTTCGTNTCC
  TGAAAATGGTTNGATTTTTACTCCNACTGTTGACCCCCGCTGCTGATCCACTAAGACTGN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006603
• ORF Size: 3696 bp
• Insert Size: 5350
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006603.3, NP_006594.3
• RefSeq Size: 5810
• RefSeq ORF: 3696
• Locus ID: 10735
• Domains: STAG
• Protein Pathways: Cell cycle
• Gene Summary: The protein encoded by this gene is a subunit of the cohesin complex, which regulates the separation of sister chromatids during cell division. Targeted inactivation of this gene results in chromatid cohesion defects and aneuploidy, suggesting that genetic disruption of cohesin is a cause of aneuploidy in human cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
  Transcript Variant: This variant (4) differs in the 5' UTR and lacks an in-frame coding exon compared to variant 1. The resulting isoform (b) is shorter, lacking an internal protein segment, compared to isoform a. Variants 3, 4 and 5 encode the same isoform.