GJB6 (NM_006783) Human Untagged Clone

CAT#: SC111169

GJB6 (untagged)-Human gap junction protein, beta 6, 30kDa (GJB6), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GJB6
• Synonyms: CX30; DFNA3; DFNA3B; DFNB1B; ECTD2; ED2; EDH; HED; HED2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC111169 sequence for NM_006783 edited (data generated by NextGen Sequencing)
  ATGGATTGGGGGACGCTGCACACTTTCATCGGGGGTGTCAACAAACACTCCACCAGCATC
  GGGAAGGTGTGGATCACAGTCATCTTTATTTTCCGAGTCATGATCCTCGTGGTGGCTGCC
  CAGGAAGTGTGGGGTGACGAGCAAGAGGACTTCGTCTGCAACACACTGCAACCGGGATGC
  AAAAATGTGTGCTATGACCACTTTTTCCCGGTGTCCCACATCCGGCTGTGGGCCCTCCAG
  CTGATCTTCGTCTCCACCCCAGCGCTGCTGGTGGCCATGCATGTGGCCTACTACAGGCAC
  GAAACCACTCGCAAGTTCAGGCGAGGAGAGAAGAGGAATGATTTCAAAGACATAGAGGAC
  ATTAAAAAGCAGAAGGTTCGGATAGAGGGGTCGCTGTGGTGGACGTACACCAGCAGCATC
  TTTTTCCGAATCATCTTTGAAGCAGCCTTTATGTATGTGTTTTACTTCCTTTACAATGGG
  TACCACCTGCCCTGGGTGTTGAAATGTGGGATTGACCCCTGCCCCAACCTTGTTGACTGC
  TTTATTTCTAGGCCAACAGAGAAGACCGTGTTTACCATTTTTATGATTTCTGCGTCTGTG
  ATTTGCATGCTGCTTAACGTGGCAGAGTTGTGCTACCTGCTGCTGAAAGTGTGTTTTAGG
  AGATCAAAGAGAGCACAGACGCAAAAAAATCACCCCAATCATGCCCTAAAGGAGAGTAAG
  CAGAATGAAATGAATGAGCTGATTTCAGATAGTGGTCAAAATGCAATCACAGGTTTCCCA
  AGCTAA
  
  Clone variation with respect to NM_006783.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006783 unedited
  AAGGGTTCACTATTTATGTTATACGACTCACTATAGGCGGCCGCGNATTCGGCACGAGGC
  CTCGTGCCGAATTCGGCACGAGGGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAG
  AGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAG
  AGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAG
  AGAGAGAGAGAGAGCTGGGAAGACGCTGGTCAGTTCACCTGCCCCACTGGTTGTTTTTTA
  AACAAATTCTGATACAGGCGACATCCTCTCTGACCGAGCAAAGATTGACATTCGTATCAT
  CACTGTGCACCATTGGCTTCTAGGCACTCCAGTGGGGTAGGAGAAGGAGGTCTGAAACCC
  TCGCAGAGGGATCTTGCCCTCATTCTTTGGGTCTGAAACACTGGCAGTCGTTGGAAACAG
  GACTCAGGGATAAACCAGCGCAATGGATTGGGGGACGCTGCACACTTTCATCGGGGGTGT
  CAACAAACACTCCACCAGCATCGGGAAGGTGTGGATCACAGTCATCTTTATTTTCCGAGT
  CATGATCCTCGTGGTGGCTGCCCAGGAAGTGTGGGGTGACGAGCAAGAGGACTTTGTCTG
  CAACACACTGCAACCGGGATGCAAAAATGTGTGCTATGACCACTTTTTCCCGGTGTCCCA
  CATCCGGCTGTGGGCCCTCCAGCTGATCTTTGTCTCCACCCCAGCGCTGCTGGTGGCCAT
  GCATGTGGCCTACCTACAGCACGAAACCACTCCCAGTTTCGGCCGAGAGAGAAGAGGATG
  ATTTTCAAGACTTAGAGACTTTAAAAGCACATGTTCCGATAGAGGGGTCCCTGGTGTGGC
  CGTACACCACAGCATTTTTTTCCGATCATCTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006783 unedited
  GAGCTTGNACCGCGCCGCAATCNANAGTCGAGTTTTTTTCTTTTTTTTTTGAAGGCTTAA
  GCAATGGGGACGAGCTTTATTGAGGCAATCACATCCACATTTCAGTTGTTTGCAATGATT
  GGCAAACGGATGAGTTAAAAAAGCCTTCTGCTTCCACACTGTTCCGTCTACATTCAGAAA
  GCAGTAAAAATATATTGTGCAATGAACACTTTCCACCTTAAGCGTATCATGACAGTTCAC
  AAATTTGCCAACAGACAATGCAAAACAATATTTACAAGATAGACCCTTTGTAAGTTCCAA
  ATTTAGATACTTGTGGTGTAATTCTAAAACTAACATCGCATGTTTTTCCAGGTAAGGAAG
  ACCAGTCATTATAAAAATACTTTATATAAATTCAAAGTCAGAACTAAAAACATCCAAGCC
  TATAAAAATATCTTTTCCTAATAAACGTATCAATTCCTGGATAAATGTTCCTTATCAACA
  ACAGTTATATAAATTTTCAGAAAGTACCCACTTTGTCAGAGAGTCCACTTAAAAGGAACC
  TGTCAAAGTGACTGCAATGCTCCTTTGTCAAGCAGTCTCTTGTTTTCAGAGATGGACCAC
  ATATTTGATTACGTTGTGTATGAATGGAGCAAGTATCCTACAAAAAGTTAACTCAAGTGT
  CTATTTATTATGAAAGTCATTTACAAACTCTTCAGGCTACAGAAGGAACTTTCAGGTTGG
  TATTGCCTTCTGGGAGAGACAGAAGTCTCCTTATGACGCAGCTACCTTTTACCTTGAAAT
  GTTTAGCCTTGGGAAACCTGTGAATGCATTTTGACCACTATCTTGAATCAGCTCATTCAT
  TTCATTCTGCTTACTCTCCTTTAAGGCATGTATGGNGNTGATTTTTTTGCGCCTGGGCTC
  TTTTTGATCTCCTAAAACAACCTTTCACCACCAAGTAGCACACCTTTGTCCACGTTAGCG
  CATGCCAATACAGACCCCGAATTCTANAATGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006783
• ORF Size: 786 bp
• Insert Size: 2050
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006783.2, NP_006774.2
• RefSeq Size: 1805
• RefSeq ORF: 786
• Locus ID: 10804
• Domains: CNX
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. All variants encode the same protein.