GPR48 (LGR4) (NM_018490) Human Untagged Clone

CAT#: SC111332

LGR4 (untagged)-Human leucine-rich repeat containing G protein-coupled receptor 4 (LGR4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LGR4
• Synonyms: BNMD17; GPR48
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_018490 edited
  ATGCCGGGCCCGCTAGGGCTGCTCTGCTTCCTCGCCCTGGGGCTGCTCGGCTCGGCCGGG
  CCCAGCGGCGCGGCGCCGCCTCTCTGCGCGGCGCCCTGCAGCTGCGACGGCGACCGTCGG
  GTGGACTGCTCCGGGAAGGGGCTGACGGCCGTGCCCGAGGGGCTCAGCGCCTTCACCCAA
  GCGCTGGATATCAGTATGAACAACATTACTCAGTTGCCAGAAGATGCATTTAAGAACTTT
  CCTTTTCTAGAAGAGCTACAATTGGCGGGCAACGACCTTTCTTTTATCCACCCAAAGGCC
  TTGTCTGGGTTGAAAGAACTCAAAGTTCTAACGCTCCAGAATAATCAGTTGAAAACAGTA
  CCCAGTGAAGCCATTCGAGGGCTGAGTGCTTTGCAGTCTTTGCGTTTAGATGCCAACCAT
  ATTACCTCAGTCCCCGAGGACAGTTTTGAAGGACTTGTTCAGTTACGGCATCTGTGGCTG
  GATGACAACAGCTTGACGGAGGTGCCTGTGCACCCCCTCAGCAATCTGCCCACCCTACAG
  GCGCTGACCCTGGCTCTCAACAAGATCTCAAGCATCCCTGACTTTGCATTTACCAACCTT
  TCAAGCCTGGTAGTTCTGCATCTTCATAACAATAAAATTAGAAGCCTGAGTCAACACTGT
  TTTGATGGACTAGATAACCTGGAGACCTTAGACTTGAATTATAATAACTTGGGGGAATTT
  CCTCAGGCTATTAAAGCCCTTCCTAGCCTTAAAGAGCTAGGATTTCATAGTAATTCTATT
  TCTGTTATCCCTGATGGAGCATTTGATGGTAATCCACTCTTAAGAACTATACATTTGTAT
  GATAATCCTCTGTCTTTTGTGGGGAACTCAGCATTTCACAATTTATCTGATCTTCATTCC
  CTAGTCATTCGTGGTGCAAGCATGGTGCAGCAGTTCCCCAATCTTACAGGAACTGTCCAC
  CTGGAAAGTCTGACTTTGACAGGTACAAAGATAAGCAGCATACCTAATAATTTGTGTCAA
  GAACAAAAGATGCTTAGGACTTTGGACTTGTCTTACAATAATATAAGAGACCTTCCAAGT
  TTTAATGGTTGCCATGCTCTGGAAGAAATTTCTTTACAGCGTAATCAAATCTACCAAATA
  AAGGAAGGCACCTTTCAAGGCCTGATATCTCTAAGGATTCTAGATCTGAGTAGAAACCTG
  ATACATGAAATTCACAGTAGAGCTTTTGCCACACTTGGGCCAATAACTAACCTAGATGTA
  AGTTTCAATGAATTAACTTCCTTTCCTACGGAAGGCCTGAATGGGCTAAATCAACTGAAA
  CTTGTGGGCAACTTCAAGCTGAAAGAAGCCTTAGCAGCAAAAGACTTTGTTAACCTCAGG
  TCTTTATCAGTACCATATGCTTATCAGTGCTGTGCATTTTGGGGTTGTGACTCTTATGCA
  AATTTAAACACAGAAGATAACAGCCTCCAGGACCACAGTGTGGCACAGGAGAAAGGTACT
  GCTGATGCAGCAAATGTCACAAGCACTCTTGAAAATGAAGAACATAGTCAAATAATTATC
  CATTGTACACCTTCAACAGGTGCTTTTAAGCCCTGTGAATATTTACTGGGAAGCTGGATG
  ATTCGTCTTACTGTGTGGTTCATTTTCTTGGTTGCATTATTTTTCAACCTGCTTGTTATT
  TTAACAACATTTGCATCTTGTACATCACTGCCTTCGTCCAAATTGTTTATAGGCTTGATT
  TCTGTGTCTAACTTATTCATGGGAATCTATACTGGCATCCTAACTTTTCTTGATGCTGTG
  TCCTGGGGCAGATTCGCTGAATTTGGCATTTGGTGGGAAACTGGCAGTGGCTGCAAAGTA
  GCTGGGTTTCTTGCAGTTTTCTCCTCAGAAAGTGCCATATTTTTATTAATGCTAGCAACT
  GTCGAAAGAAGCTTATCTGCAAAAGATATAATGAAAAATGGGAAGAGCAATCATCTCAAA
  CAGTTCCGGGTTGCTGCCCTTTTGGCTTTCCTAGGTGCTACAGTAGCAGGCTGTTTTCCC
  CTTTTCCATAGAGGGGAATATTCTGCATCACCCCTTTGTTTGCCATTTCCTACAGGTGAA
  ACGCCATCATTAGGATTCACTGTAACGTTAGTGCTATTAAACTCACTAGCATTTTTATTA
  ATGGCCGTTATCTACACTAAGCTATACTGCAACTTGGAAAAAGAGGACCTCTCAGAAAAC
  TCACAATCTAGCATGATTAAGCATGTCGCTTGGCTAATCTTCACCAATTGCATCTTTTTC
  TGCCCTGTGGCGTTTTTTTCATTTGCACCATTGATCACTGCAATCTCTATCAGCCCCGAA
  ATAATGAAGTCTGTTACTCTGATATTTTTTCCATTGCCTGCTTGCCTGAATCCAGTCCTG
  TATGTTTTCTTCAACCCAAAGTTTAAAGAAGACTGGAAGTTACTGAAGCGACGTGTTACC
  AAGAAAAGTGGATCAGTTTCAGTTTCCATCAGTAGCCAAGGTGGTTGTCTGGAACAGGAT
  TTCTACTACGACTGTGGCATGTACTCACATTTGCAGGGCAACCTGACTGTTTGCGACTGC
  TGCGAATCGTTTCTTTTAACAAAGCCAGTATCATGCAAACACTTGATAAAATCACACAGC
  TGTCCTGCATTGGCAGTGGCTTCTTGCCAAAGACCTGAGGGCTACTGGTCCGACTGTGGC
  ACACAGTCGGCCCACTCTGATTATGCAGATGAAGAAGATTCCTTTGTCTCAGACAGTTCT
  GACCAGGTGCAGGCCTGTGGACGAGCCTGCTTCTACCAGAGTAGAGGATTCCCTTTGGTG
  CGCTATGCTTACAATCTACCAAGAGTTAAAGACTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_018490 unedited
  NGTCTTTTCCCGCCCGTTGCCGCATTGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATA
  AGCAGAGCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCG
  CGAATTCGGCACGAGGGGGGTTTGGGAACCAGAGCGTGCAACCCTAGAAGGGAAAAGGAC
  GGGAAGAGATTGAGCCGCGGCTGGGAGACAGCGAGCCAGAGTCTGGGTGTTTGTGCGAGA
  GCCACGGCGGGGGCTGGGGCGAGTGGCCGGCATGGCTGAAGGCTGCGCTCTGCAACCTTG
  AAGAGCCGCTGCATTGAGAGGCCAGGGACAGGGAGACCGGTGCGATGGCAGAGCGCGGCC
  CCCGCCGCTGCGCCGGGCCGGCCCGGCTGGCGTGAGCCGCCGGAGGAGCGGGGCTGCCTC
  TGCGCGTCCATGGAGCAGCGGGAAGGGCGAAACTCCGGAGCGCCGCGTCCCTGCGCCGCT
  GCGGCGGACTGCTGAAGGGGCCGAGCCCGCGCGGACCGCCGAGGAAGAGACCCCCGCTCC
  AGCCCGCAGGCCGGCTGCCCGGGGGCGGCGGGGGACATCGGAGGGCAGCGGAGCGAGCAG
  CGCCGCGGGAGAGGCCGGCGCGGGAGGCGGCCGCAGCAATGCCGGGCCCGCTAGGGCTGC
  TCTGCTTCCTCGCCCTGNGGCTGCTCGGCTCGGCCGGGCCCAGCGGCGCGGCGCCGNCTC
  TCTGCGCGGCGCCCTGCAGCTGCGACGGCGACCGTCGGGTGGACTGCTCCGGGAAGGGGC
  TGACNGCCGTGCCCGAGGGCTCAGCCCTTCACCCAGCGCTGGTATCAGTATGAACACATT
  ACTCAGTGCCAGAAGATGCATTTAGAACTTNCTTTTTCTAGAGAGCTACATTGGCGGNCA
  CGACCTTTCTTTTATCACCAAGGNCTTGTCTGGGTTGAAGAACTC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_018490 unedited
  ATGTACCGCGGCACGCAATCTAGTAGTCGGTTTTTTTTTTTTTTTTTTGCTTTCTAAAAA
  CTTTAATAATTCAAAACACTGAGTACAATATTGTATTTCATACCATATAGCACAAAGATT
  AACACTTTTATATATCTGTTATTCTAGTTTTTAAATGAATAAAATGAAAAATTTTCAATA
  ACCTGAATTTTGGAAAAAACCTTTTAATTAAGAGTTTCTTACCAAGTTATGATTTAATAT
  TTATCAGATGTGTAAATATACATGATAGCAATTTTTAAAACTTGTAAATAGTTGGCCTTA
  CAAAATTACAACACACCTGGCAAATAAATCCTTCCCACATTTTATACAAACTACATGATT
  TTGATATACAAAGATTCTGTTTTTATTACACTGACAATGCACAACAAAGACTATTTACAA
  TGCAAAAAGTATATAAACCACAATTTAACAGTCTGCTACTGGCAGCCACTATAGTTTAAG
  AGGTAGCTTTATTTAAACGAAATGAACAGAAGCCCCATTTCCCAACTTGTGGTCTAAAAA
  TAATTTACATAAGATAAAAATTCATTATATGCACAGTATGCTCAGTCTATCATTAAACCC
  GAATCCAGCTGGCATTTTTTATTTTTCCAGATTACCTAATATGGCGCTCGGGCTTCCTCT
  TGTTCTTAACCACTGCTCAAAAAACTTTCGGACACTTTTACTTTTAGAATCTACCCATTA
  TTAGTTCCAAAGCCCCATACCGGGAACTCAGCACACCTCCTATTTTTTAAAACCCAAGAC
  CAACCCGCACACCTCCTACTCACTTTGTATTAACAACTTTTTTACCTGTGAACCCAAACT
  CACCCTCGAGACCTTTCGATTGGCCCTCCTCCATAAAATTCTCGGGAAACATCTGGCAAT
  TCCCCTTCTTTCTCTCGTGTCATTATTTCCCTTCTTAATAACTCCGGAGCCTACGCCGCT
  TAACACTCCCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_018490
• ORF Size: 2856 bp
• Insert Size: 5400
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_018490.1, NP_060960.1
• RefSeq Size: 5211
• RefSeq ORF: 2856
• Locus ID: 55366
• Domains: 7tm_1, LRRNT, LRR, LRR_TYP, LRR_BAC, LRR_PS
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Gene Summary: The protein encoded by this gene is a G-protein coupled receptor that binds R-spondins and activates the Wnt signaling pathway. This Wnt signaling pathway activation is necessary for proper development of many organs of the body. [provided by RefSeq, Oct 2016]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).