IGLL1 (NM_020070) Human Untagged Clone

CAT#: SC111642

IGLL1 (untagged)-Human immunoglobulin lambda-like polypeptide 1 (IGLL1), transcript variant 1


  "NM_020070" in other vectors (6)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol IGLL1
Synonyms 14.1; AGM2; CD179b; IGL1; IGL5; IGLJ14.1; IGLL; IGO; IGVPB; VPREB2
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_020070 edited
GAATTCGGCACGAGATGGACTGGGGTGCAATGGGACAGCTGCTGCCAGCGAGAGGGACCA
GGGCACCACTCTCTAGGGAGCCCACACTGCAAGTCAGGCCACAAGGACCTCTGACCCTGA
GGGCCGATGAGGCCAGGGACAGGCCAGGGGGGCCTTGAGGCCCCTGGTGAGCCAGGCCCC
AACCTCAGGCAGCGCTGGCCCCTGCTGCTGCTGGGTCTGGCCGTGGTAACCCATGGCCTG
CTGCGCCCAACAGCTGCATCGCAGAGCAGGGCCCTGGGCCCTGGAGCCCCTGGAGGAAGC
AGCCGGTCCAGCCTGAGGAGCCGGTGGGGCAGCAGGTTCCTGCTCCAGCGCGGCTCCTGG
ACTGGCCCCAGGTGCTGGCCCCGGGGGTTTCAATCCAAGCATAACTCAGTGACGCATGTG
TTTGGCAGCGGGACCCAGCTCACCGTTTTAAGTCAGCCCAAGGCCACCCCCTCGGTCACT
CTGTTCCCGCCGTCCTCTGAGGAGCTCCAAGCCAACAAGGCTACACTGGTGTGTCTCATG
AATGACTTTTATCCGGGAATCTTGACGGTGACCTGGAAGGCAGATGGTACCCCCATCACC
CAGGGCGTGGAGATGACCACGCCCTCCAAACAGAGCAACAACAAGTACGCGGCCAGCAGC
TACCTGAGCCTGACGCCCGAGCAGTGGAGGTCCCGCAGAAGCTACAGCTGCCAGGTCATG
CACGAAGGGAGCACCGTGGAGAAGACGGTGGCCCCTGCAGAATGTTCATAGGTTCCCAGC
CCCGACCCCACCCAAAGGGGCCTGGAGCTGCAGGATCCCAGGGGAAGGGTCTCTCTCTGC
ATCCCAAGCCATCCAGCCCTTCTCCCTGTACCCAGTAAACCCTAAATAAATACCCTCTTT
GTCAACCAGAAAAAAAAAAAAAAAAAACTCGAC
>OriGene 5' read for NM_020070 unedited
CGCGTTCAGGCATATTTGTNAATACGAACTTTACTTTGAGGGNNCGGCCGCGNAATTCGG
CACGAGATGGACTGGGGTGCAATGGGACAGCTGCTGCCAGCGAGAGGGACCAGGGCACCA
CTCTCTAGGGAGCCCACACTGCAAGTCAGGCCACAAGGACCTCTGACCCTGAGGGCCGAT
GAGGCCAGGGACAGGCCAGGGGGGCCTTGAGGCCCCTGGTGAGCCAGGCCCCAACCTCAG
GCAGCGCTGGCCCCTGCTGCTGCTGGGTCTGGCCGTGGTAACCCATGGCCTGCTGCGCCC
AACAGCTGCATCGCAGAGCAGGGCCCTGGGCCCTGGAGCCCCTGGAGGAAGCAGCCGGTC
CAGCCTGAGGAGCCGGTGGGGCAGCAGGTTCCTGCTCCAGCGCGGCTCCTGGACTGGCCC
CAGGTGCTGGCCCCGGGGGTTTCAATCCAAGCATAACTCAGTGACGCATGTGTTTGGCAG
CGGGACCCAGCTCACCGTTTTAAGTCAGCCCAAGGCCACCCCCTCGGTCACTCTGTTCCC
GCCGTCCTCTGAGGAGCTCCAAGCCAACAAGGCTACACTGGTGTGTCTCATGAATGACTT
TTATCCGGGAATCTTGACGGTGACCTGGAAGGCAGATGGTACCCCCATCACCCAGGGCGT
GGAGATGACCACGCCCTCCANACAGAGCAACAACAAGTACGCGGCCAGCAGCTACCTGAG
CCTGACGCCCGAGCAGTGGAGGTCCCGCAGAAGCTACAGCTGCCAGGTCATGCACGAAAG
GAGCACCGTGGAGAAGACGGTGGCCCCTGCAGAAATGTCATAGGTTCCCAGCCCCGACCC
CACCCAAAGGGCCTGGAGCTGCAAGATCCCANGGGAAGGGTCTTCTCTGCATCCCAGCCA
TNCAGCCTTCTNCCTGTACCCATAAACCCTAATAATACCC
>OriGene 3' read for NM_020070 unedited
TGGGGCCCAATACCGCCTACTTTCCCCCCCCCGGAATCGTGTNCCGCGGCCGCATTTTAT
GATCGGTTTTTTTTTTTTTTTTTTCTGGGTGACAAACAGGTTTTTATTTAGGGTTTACTG
GGGTACAGGGTAGAAAGGGGCTGGTATGGCCTTGGGCATGCACGAGAGAGACCCTTCCCC
TGGGATCCTGCAGCTCCAGGCCCCTTTGGGTGGGGTCGGGGCTGGGAACCTATGAACATT
CTGCAGGGGCCACCGTCTTCTTTACTGTGCTCCCTTCGTGCATGACCTGGCAGCTGTAGC
TTCTGCGGGACCTCCACTGCTCGGGCGTCAGGCTCAGGTAGCTGCTGGCCGCGTACTTGT
TGTTGCTCTGTTTGGAGGGCGTGGTCATCTCCACGCCCTGGGTGATGGGGGTACCATTTG
CCTTCCAGGTCACCGTCAAGATTCCCGGATAAAAGTCATTCATGAGACACACCAGTGTAG
CCTTGTTGGCTTGGAGCTCCTCATAGGACGGGGGGAACAGAGTGACCGAAGGGGTGGCCT
TGGGCTGACTTAAACGGTGAGCTGGGCCCGCTGCCAAAACACATGCCGCACTGAGTATGC
TTGGATTGAACCCCCGGGGCCAGCACCTGGGGCCCAGTCCAGGAGCCGCGCTGGACCAGG
ACCCTGCTTGCCCCACCGGCTCCCTCAGCTTGGACCGCTTGCTTTCTTCCAGGGGCCTCC
AGGGGCCCAGGCCCCTGCTTTGGCATGCAATTTGTTTGGCCCCCCAGGCCATTGGTTACC
ACGGCCAAACCCCCCACACCAAGGGCCCCCCCTTCCCTGAGGTTGGGGCCCGGCCTCCAC
AGGGGCCTCAAGGGCCCCCTGGCCTTGGCCTTGCCCCTAATCGGCCCTTAGGGTCAAAAA
GTCCCTTGGGGCCCGAATTCCACCGGGGGGCCCCCTCTAAAAGGGGGGCCCTGGGCCCCT
TTTCTTGGAGACCAGATGTTCCATTTGACCCTCAGAACCCTCTTTTGCCCCAAATTTACG
GGCCCCCCTCTATAGGCAGG
Restriction Sites NotI-NotI     
ACCN NM_020070
Insert Size 980 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_020070.2, NP_064455.1
RefSeq Size 901 bp
RefSeq ORF 642 bp
Locus ID 3543
Cytogenetics 22q11.23
Domains ig, IGc1
Protein Families Secreted Protein
Protein Pathways Primary immunodeficiency
Gene Summary 'The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).

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