Liprin alpha 1 (PPFIA1) (NM_003626) Human Untagged Clone

CAT#: SC111709

PPFIA1 (untagged)-Human protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 (PPFIA1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PPFIA1
• Synonyms: LIP.1; LIP1; LIPRIN
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC111709 sequence for NM_003626 edited (data generated by NextGen Sequencing)
  ATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGA
  GGCCATGGTTCCGGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATG
  GTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTGAGAGAGACTCAAGAAACG
  CTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGA
  CAGCTCAACACGGCACTTCCACAGGAGTTCGCAGCACTTACTAAAGAACTCAATGTATGC
  AGGGAACAGCTCCTTGAAAGGGAAGAAGAAATTGCTGAACTGAAAGCAGAAAGGAATAAC
  ACCAGGCTGCTGTTAGAGCATTTGGAATGCCTTGTCTCCAGGCATGAGCGGTCTCTTAGG
  ATGACCGTGGTGAAGAGACAAGCGCAGTCTCCAGCAGGCGTGTCCAGCGAAGTGGAAGTG
  CTGAAAGCACTGAAGTCCTTATTTGAACACCACAAAGCTCTGGATGAAAAGGTGAGAGAG
  CGATTACGAGTAGCACTTGAAAGATGTAGTTTGTTAGAAGAGGAATTAGGTGCCACACAC
  AAAGAGCTAATGATTCTTAAAGAACAGAATAATCAGAAAAAAACTCTAACAGATGGAGTG
  CTGGACATAAACCATGAACAAGAAAATACACCAAGCACGAGTGGAAAGAGATCTTCTGAT
  GGTTCTTTAAGCCACGAGGAAGACCTTGCTAAAGTAATTGAGCTCCAAGAAATCATAAGT
  AAGCAGTCAAGGGAACAGAGCCAAATGAAAGAACGCCTGGCTTCCCTTTCCAGTCATGTG
  ACAGAACTGGAAGAGGATCTGGACACGGCTAGAAAAGATCTCATCAAATCTGAAGAAATG
  AACACAAAATTGCAACGAGATGTCCGTGAAGCCATGGCCCAAAAGGAAGATATGGAAGAG
  AGAATCACTACTCTTGAAAAACGCTACCTCGCTGCACAGCGTGAAGCCACATCTGTGCAT
  GACCTCAATGATAAACTTGAAAATGAAATTGCAAATAAAGATTCTATGCATCGACAGACT
  GAAGATAAAAACCGCCAGTTACAGGAGCGCTTGGAATTGGCAGAGCAAAAGCTGCAACAG
  ACACTGAGGAAGGCAGAGACGCTCCCGGAGGTGGAGGCGGAGCTGGCCCAGAGGGTGGCA
  GCGCTTTCCAAGGCTGAAGAGAGACACGGCAACATTGAAGAAAGGTTACGACAGATGGAA
  GCACAGTTGGAGGAGAAGAATCAAGAACTGCAGCGGGCAAGGCAAAGAGAAAAAATGAAC
  GAAGAACATAATAAACGTTTATCAGACACTGTTGACAAGCTGCTTTCAGAATCTAATGAG
  AGGCTTCAACTTCATCTTAAAGAGAGAATGGCTGCTTTGGAAGATAAGAACTCTCTTTTA
  AGAGAAGTTGAAAGTGCAAAAAAGCAGTTAGAAGAAACACAACACGATAAGGATCAGCTT
  GTCCTAAACATTGAAGCACTGAGGGCTGAACTAGACCACATGAGACTAAGAGGTGCTTCA
  CTTCATCATGGCCGACCCCACTTGGGCAGTGTCCCAGATTTCAGGTTCCCCATGGCAGAC
  GGCCACACAGACTCCTACAGCACCAGTGCAGTGCTGCGGCGCCCACAGAAAGGCCGGCTG
  GCAGCCCTGCGAGATGAGCCTTCCAAGGTACAAACTCTTAATGAGCAGGATTGGGAACGT
  GCCCAGCAAGCTAGTGTCTTGGCAAATGTAGCACAAGCATTCGAGAGTGATGCTGACGTG
  TCTGATGGTGAAGATGACAGGGACACTCTCCTCAGCTCAGTTGACCTGCTATCGCCCAGC
  GGGCAGGCCGACGCGCACACACTAGCCATGATGCTTCAGGAGCAGCTGGACGCCATCAAC
  AAAGAGATCAGGTTGATTCAGGAAGAAAAAGAAAATACAGAGCAGCGGGCAGAGGAGATT
  GAAAGTCGAGTTGGCAGTGGAAGTCTAGACAATCTTGGTCGTTTTAGATCAATGAGCTCC
  ATTCCCCCCTACCCTGCTTCCTCGCTTGCTAGCTCCTCCCCTCCGGGCAGTGGGCGCTCC
  ACCCCACGAAGGATCCCTCACAGCCCAGCTCGGGAAGTGGACAGACTGGGCGTCATGACC
  CTTTTGCCACCTTCCAGAGAAGAGGTACGAGATGACAAGACAACCATAAAGTGTGAAACC
  TCCCCGCCTTCCTCCCCGAGAGCCCTTCGGTTAGACCGGCTGCACAAAGGGGCGCTGCAC
  ACCGTCAGCCACGAGGACATCAGGGACATAAGGAACTCCACAGGCTCCCAGGATGGTCCC
  GTGAGCAACCCCAGCAGTAGCAACAGTAGCCAGGACTCGCTCCACAAAGCCCCAAAGAAG
  AAAGGCATTAAGTCCTCCATTGGCCGCTTGTTTGGCAAGAAAGAAAAGGGCCGACCTGGA
  CAAACTGGCAAAGAAGCATTAGGACAAGCTGGTGTTTCCGAGACGGATAACTCATCTCAG
  GATGCCTTGGGACTTAGCAAATTGGGGGGACAGGCTGAAAAAAATCGTAAACTTCAAAAA
  AAGCATGAATTGCTGGAGGAAGCCCGGAGACAAGGTTTACCTTTTGCCCAATGGGACGGG
  CCAACGGTTGTGGTCTGGCTAGAGCTCTGGGTTGGGATGCCAGCCTGGTATGTGGCTGCC
  TGCCGAGCAAACGTGAAAAGCGGGGCCATCATGTCGGCCCTGTCCGACACAGAGATCCAG
  CGTGAGATTGGCATCAGCAACCCCCTGCACAGGCTGAAGCTGAGGCTGGCCATCCAGGAG
  ATCATGTCGCTGACCAGCCCGTCTGCCCCGCCCACATCTAGAACGACACTCGCCTATGGG
  GACATGAACCACGAGTGGATCGGCAACGAGTGGCTCCCCAGCCTGGGCCTCCCCCAGTAC
  CGCAGCTACTTCATGGAGTGCCTTGTAGACGCCAGGATGCTGGACCACTTGACCAAGAAA
  GACCTTCGAGGGCAGCTGAAAATGGTCGACAGTTTTCACAGAAACAGTTTCCAGTGTGGA
  ATTATGTGCCTGAGAAGGTTAAATTATGACCGGAAAGAACTGGAAAGAAAAAGAGAAGAA
  AGTCAGAGTGAAATAAAAGACGTGCTTGTTTGGAGCAATGATCGAGTGATTCGCTGGATC
  CTGTCAATTGGCCTTAAAGAATATGCAAACAATCTTATAGAGAGTGGTGTTCACGGAGCA
  CTTCTGGCCTTAGATGAAACCTTCGACTTCAGTGCACTGGCACTGCTGTTACAGATCCCG
  ACGCAGAACACACAGGCTCGTGCTGTCTTGGAAAGAGAATTTAACAACCTTTTGGTCATG
  GGGACTGATAGAAGGTTTGATGAAGATGATGATAAAAGCTTTAGGAGAGCACCTTCATGG
  AGAAAAAAGTTTAGACCAAAGGACATTCGTGGCTTAGCTGCTGGGTCAGCAGAGACTCTC
  CCTGCAAACTTCCGGGTGACTTCTTCTATGTCTTCCCCCTCTATGCAGCCAAAGAAGATG
  CAGATGGACGGCAATGTATCAGGAACACAGAGGTTGGATTCTGCTACAGTCAGGACTTAC
  TCCTGCTAA
  
  Clone variation with respect to NM_003626.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003626 unedited
  CCTATAGGCGGCCGCGTATTCGGCACGAGGGGATAGAGAGAGAGAGAGAGAGAGAGAGAG
  AGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAG
  AGAGAGAGAGAGAGAGAGAGAGAGAGAGCGCAGCCGGGCCCGCTCCTCCTCCGCTCCGCC
  AGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGCGGCGTG
  GGGCGGGCAGGCGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAG
  CGAGCAGCCGCCCGCGAGCCGCCGCGGAGCCTCCTCGCCCGCTCCCGCCGGCGAGCAAGA
  TGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAG
  GCCATGGTTCCGGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGG
  TCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTGAGAGAGACTCAAGAAACGC
  TGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGAC
  AGCTCAACACGGCACTTCCACAGGAGTTCGCAGCACTTACTAAAGAACTCAATGTATGCA
  GGGAACAGCTCCTTGAAGGGAAGAAGAAATTGCTGAACTGAAAGCAGAAAGGAATACACC
  CGGCTGCTGTTAGAGCATTTGGAATGCCTTGTCTCCAGGCTGAGCGGTCTCTTTAGATGA
  CCGTGGTGAAGAGACAAGCGCCGTCTCCACCAGGCGTGTTCCCCGAATGGAAATGCTGAA
  AGCACTGAAGTTCTTTTTTGACACCCCCAAGCTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003626 unedited
  GCTATGGACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTGGCAGGGGAAAATGCTTCAGTACTTTATTGAAAGAAAGCAATAAATAATACTGGGA
  TAAAAATAGTTCAAAAGTAGACTGGACATACTTTGTTACATAATCAGGAAGTTGACAAAA
  GATTAATAGAAAAACAGAACAGTAACAATGAATTGGACAAGTAAATTAAAAGCAGAAACC
  AACTGAAAAGACAGGCTGCCTTTGTCTCTGGATCTGCTGGACAATAAATACCACGCCATG
  GTCTGACACACTTTGCTGGCTTGGTAATATGCCATTTAAAAAGTAAAAGCCACATCTGGA
  ACTTACACAATCCAAAATGGGTAGAGCATTAAAGTCTAAAAATGGCCCACTAGGGTCGGT
  CTTTAAACATGTTTACAAACAAATGTTAAAAGATGATTTACATAAGAAAAATAAGGCCTT
  TATTAAAGCTGCACTGGACTGGTTTCTGGGTCTCCTGGCTTCATCCACTGTGTGCGCCGA
  CTTGCACGATGAAAGCGTGGTGCTTGGTGCTGGCCCTAAGGGGAGCCACATGGGTGTCTC
  TCCACCCCCTCCCAAGGAGCATAGGCAGGGAAGAGGGTGCAGGGGCTACACTGGTCCCCA
  GGTTACCCCATCCCGAGGCTCTTCAGCTGAGAGAACTGGTCCCAGCTTACAGTCTTAGGC
  ACTGAAGACAAGCTCCCCCAATCCCGAGACCATGCTATGAAAGCGTTAACCAGCGCCAGG
  GGCTTCTCATATGTTGGGACAGTGCTCCACGCCCCACTTATTAGACCTGTTATTTACCCC
  AGCCATTTTAATTTGGCCATGCTGCAGAAAAAACATTCTTTGCTAAAAAAGAACGTTACG
  CCCGCCTGAAAAACCACACTGCTGAATTAAGCATGCTATTTCAGAAGATGCTGAAAGCTA
  GTTTGTCCGTAAAGATAAGCCACGCTTTTCGCTAATTCTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003626
• ORF Size: 3609 bp
• Insert Size: 5650
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003626.2, NP_003617.1
• RefSeq Size: 5227
• RefSeq ORF: 3609
• Locus ID: 8500
• Domains: SAM
• Protein Families: Druggable Genome, Phosphatase
• Gene Summary: The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) represents the longest transcript and it encodes the longer protein (isoform b).