Claudin 10 (CLDN10) (NM_006984) Human Untagged Clone

CAT#: SC111728

CLDN10 (untagged)-Human claudin 10 (CLDN10), transcript variant b

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CLDN10
• Synonyms: CPETRL3; HELIX; OSP-L; OSPL
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC111728 sequence for NM_006984 edited (data generated by NextGen Sequencing)
  ATGGCTAGCACGGCNTCGGAGATCATCGCCTTCATGGTCTCCATCTCAGGCTGGGTACTG
  GTGTCCTCCACGCTGCCCACCGACTACTGGAAGGTGTCTACCATCGACGGCACGGTCATC
  ACAACCGCCACCTATTGGGCCAACCTGTGGAAGGCGTGCGTTACCGACTCCACGGGCGTC
  TCCAACTGCAAGGACTTCCCCTCCATGCTGGCGCTGGACGGTTATATACAGGCATGTAGA
  GGACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTTGCGCTCTTTGGA
  ATGAAGTGTACCAAAGTCGGAGGCTCCGATAAAGCCAAAGCTAAAATTGCTTGTTTGGCT
  GGGATTGTATTCATACTGTCAGGGCTGTGCTCAATGACTGGATGTTCCCTATATGCAAAC
  AAAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAGTATGAATTAGGAGCC
  GCTCTGTTTATTGGATGGGCAGGAGCCTCACTGTGCATAATTGGTGGTGTCATATTTTGC
  TTTTCAATATCTGACAACAACAAAACACCCAGATACACATACAACGGGGCCACATCTGTC
  ATGTCTTCTCGGACAAAGTATCATGGTGGAGAAGATTTTAAAACAACAAACCCTTCAAAA
  CAGTTTGATAAAAATGCTTATGTCTAA
  
  Clone variation with respect to NM_006984.4
  15 t=>n
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006984 unedited
  TCTANCATTTGTATACGACTTATATAGGCGGCCGACGAATTCGCACGAGGCGAGCGCGGC
  TGCAGCCGGCGGCATGGCTAGCACGGCTTCGGAGATCATCGCCTTCATGGTCTCCATCTC
  AAGCTGGGTACTGGTGTCCTCCACGCTGCCCACCGACTACTGGAAGGTGTCTACCATCGA
  CGGCACGGTCATCACAACCGCCACCTATTGGGCCAACCTGTGGAAGGCGTGCGTTACCGA
  CTCCACGGGCGTCTCCAACTGCAAGGACTTCCCCTCCATGCTGGCGCTGGACGGTTATAT
  ACAGGCATGTAGAGGACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATT
  TGCGCTCTTTGGAATGAAGTGTACCAAAGTCGGAGGCTCCGATAAAGCCAAAGCTAAAAT
  TGCTTGTTTGGCTGGGATTGTATTCATACTGTCAGGGCTGTGCTCAATGACTGGATGTTC
  CCTATATGCAAACAAAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAGTA
  TGAATTATGAGCCGCTCTGTTTATTGGATGGGCAGGAGCCTCACTGTGCATAATTGGTGG
  TGTCATATTTTGCTTTTCAATATCTGACAACAACAAAACACCCAGATACACATACAACGG
  GGCCACATCTGTCATGTCTTCTCGGACAAAGTATCATGGTGGAGAAGATTTTAAAACAAC
  AAACCCTTCAAAACAGTTTGATAAAAATGCTTATGTCTAAAAGAGCTCGCTGGCAAGCTG
  CCTCTTGAGTTTGTTATAAAAGCGAACTGTTCACAAAATGATCCCATCAGGNCCCTNCCC
  ATATTAACACTCAAAACTATTTTTAAATATGCATTTGAAGCATCTGTGATGTATGGATGT
  AAGNNTGTCTACATAGTAGTATATACTATCATTTGCTGTGAGGCTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006984 unedited
  GCCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCAGGTATGGAATTTTTT
  TTATTTTTTATCTTTTAACAAACTTGTTCATTTCCTTTTCTTTCCATTGAGCACCTCTGA
  ACAATGTGATTCTTTTTTTTAAGTCTTTCACACTTCAGGAAAATACTACATTCACCCACG
  TTGTGATTCATATCGGACAGTTTCTTACTCAAAGATAACACAAATACCAATTCTTATTCA
  TACTTTGAAACTATATTTTACCCTAGACTGCCTTGGTTCAAAGGCCTAGTTTCGACATTA
  CTGTGGCAAATTATTTAAGCTCTCTGTTTTCATTTCTTTTTCTGTAAATGCAGGATGAAA
  ACAATATGTATCTCCTAGGATGGCTGTGAGGAGTGAGTGAAACAGGACATGAAAGGTGTG
  TATGAACTGTGATAACTGTTGCCCTTGTGGGCATGTTATATAGGGCTGGCTCTAGGAAGA
  AGCCTGTGTCTTTTTTCAGAAATCCCTGGAGCAACTTAAATGTCTTTAGAAATGACAAGT
  CTCTCAGTTATCCAGTTAGCCGTAAACAGGTTCTGGAAGACACACCTAGATAGAACTCGG
  CCCGTCAGTTCTGAGTGAGGCACGTACCACTTGGGCTTGGGATGTCCTTAACCCATTTAT
  GCCTGAGGTTTGCATTTTTTGAATTTTTCCATTCACACCTTGCCGATGACCTTGAGCAGT
  AGGATATAAATACCTCCCACTGCTTAGTGTCCCAATATGGGACCCTAGGCATAAACAGTT
  TTAATTGGCTCTCAGTCACCCTGACCATATCTCTTCCTAGCTTTGCTGAGCCCTACCCAA
  GCTTTGCTTTCGGGCAGGGACCCTCACCCCTTACATGGTGGGCCATGACAGCAATATTTT
  TGCCCCATTACCTTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006984
• ORF Size: 687 bp
• Insert Size: 2500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006984.3, NP_008915.1
• RefSeq Size: 2373
• RefSeq ORF: 687
• Locus ID: 9071
• Domains: PMP22_Claudin
• Protein Families: Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction
• Gene Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined. [provided by RefSeq, Jun 2010]
  Transcript Variant: This variant (b) differs in the 5' UTR and 5' coding region, representing use of an alternate promoter, compared to variant a. The resulting isoform (b) has a longer and distinct N-terminus, compared to isoform a.